Sachin Kumar Singh
Lovely Professional University
Internal medicineSolubilityNanotechnologyIntensive care medicineBioavailabilityChemistryMaterials scienceDiseaseSpray dryingDrug deliveryDrugChemical engineeringChromatographyDiabetes mellitusTraditional medicineMedicineDosage formZeta potentialBiologyDissolutionPharmacology
206Publications
19H-index
1,211Citations
Publications 215
Newest
#1Yinghan ChanH-Index: 4
#2Sin Wi NgH-Index: 5
Last. Sachin Kumar SinghH-Index: 19
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#1Yinghan Chan (International Medical University)H-Index: 4
#2Sin Wi Ng (International Medical University)H-Index: 5
Last. Raimar Löbenberg (University of Alberta Faculty of Pharmacy and Pharmaceutical Sciences)H-Index: 34
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Viral respiratory tract infections have significantly impacted global health as well as socio-economic growth. Respiratory viruses such as the influenza virus, respiratory syncytial virus (RSV), and the recent SARS-CoV-2 infection (COVID-19) typically infect the upper respiratory tract by entry through the respiratory mucosa before reaching the lower respiratory tract, resulting in respiratory disease. Generally, vaccination is the primary method in preventing virus pathogenicity and it has been...
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#1Leander Corrie (LPU: Lovely Professional University)H-Index: 5
#2Monica Gulati (LPU: Lovely Professional University)H-Index: 23
Last. Niraj Kumar Jha (Sharda University)H-Index: 11
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Abstract null null Polycystic ovarian syndrome (PCOS) is the primary cause of female infertility affecting several women worldwide. Changes in hormonal functions such as hyperandrogenism are considered a significant factor in developing PCOS in women. In addition, many molecular pathways are involved in the pathogenesis of PCOS in women. To have better insights about PCOS, it is data from clinical studies carried on women suffering from PCOS should be collected. However, this approach has severa...
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#1Khalid Saad AlharbiH-Index: 11
Last. Niraj Kumar Jha (Sharda University)H-Index: 11
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Nuclear factor-kappa B, involved in inflammation, host immune response, cell adhesion, growth signals, cell proliferation, cell differentiation, and apoptosis defense, is a dimeric transcription factor. Inflammation is a key component of many common respiratory disorders, including asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and acute respiratory distress syndrome. Many basic transcription factors are found in NF-κB signaling, which is a member of the Rel protein family...
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#1Ankur Sharma (Sharda University)H-Index: 2
#2Dhruv Kumar (Amity University)H-Index: 16
Last. R. B. SrivastavaH-Index: 3
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The increasing burden of respiratory diseases caused by microbial infections poses an immense threat to global health. This review focuses on the various types of biofilms that affect the respiratory system and cause pulmonary infections, specifically bacterial biofilms. The article also sheds light on the current strategies employed for the treatment of such pulmonary infection-causing biofilms. The potential of nanocarriers as an effective treatment modality for pulmonary infections is discuss...
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#1Krishnan Anand (University of the Free State)H-Index: 16
#2Chithravel Vadivalagan (TMU: Taipei Medical University)H-Index: 10
Last. Kamal Dua (UTS: University of Technology, Sydney)H-Index: 28
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Extracellular vesicles like exosomes are important therapeutic tactics for treating COVID -19. By utilizing convalescent plasma derived exosomes (CPExo) from COVID-19 recovered persistence could accelerate the treatment strategies in the current state of affairs. Adequate literature has shown that administering the exosome to the in vivo system could be beneficial and could target the pathogens in an effective and precise manner. In this hypothesis we highlight the CPExo instead of convalescent ...
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#1Nitin Chitranshi (Macquarie University)H-Index: 14
#2Ashutosh KumarH-Index: 21
Last. Devaraj BasavarajappaH-Index: 6
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Amyloid precursor protein (APP), upon proteolytic degradation, forms aggregates of amyloid β (Aβ) and plaques in the brain, which are pathological hallmarks of Alzheimer’s disease (AD). Cathepsin B is a cysteine protease enzyme that catalyzes the proteolytic degradation of APP in the brain. Thus, cathepsin B inhibition is a crucial therapeutic aspect for the discovery of new anti-Alzheimer’s drugs. In this study, we have employed mixed-feature ligand-based virtual screening (LBVS) by integrating...
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#1Gaurav Gupta (Gyanvihar University)H-Index: 30
#2Roshan S (Osmania University)
Last. Kamal Dua (UTS: University of Technology, Sydney)H-Index: 28
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COVID-19's second wave had a significant impact on India, on May 7, 2021, the largest daily recorded case count was a little more than 4 million, and it has since fallen. Although the number of new cases reported has dropped, during the third week of May 2021, India accounted for about 45% of new cases identified globally and around 34% of deaths. As India maintains its present level of stability, a new urgent threat has emerged in the form of coronavirus-associated mucormycosis. Mucormycosis, a...
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#1Ankur Sharma (Ulster University)H-Index: 1
#2Susan Hawthorne (Ulster University)H-Index: 10
Last. Harish Dureja (Maharshi Dayanand University)H-Index: 18
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Aim: This study was aimed at evaluating the anticancer potential of curcumin-loaded poly(lactic-co-glycolic acid) (PLGA) based nanoparticles (NPs) in MDA-MB231 human breast cancer cells. Methods: Curcumin-loaded PLGA NPs were developed using a modified solvent evaporation technique. Physical characterization was performed on the formulated NPs. Furthermore, in vitro experiments were conducted to study the biological activity of the curcumin-loaded NPs. Results: Curcumin-loaded PLGA NPs demonstra...
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#1Leander Corrie (LPU: Lovely Professional University)H-Index: 5
#2Monica Gulati (LPU: Lovely Professional University)H-Index: 23
Last. Rubiya Khursheed (LPU: Lovely Professional University)H-Index: 9
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Polycystic ovarian syndrome (PCOS) is a combination of various symptoms like anovulation, hirsutism, chronic amenorrhea, infertility, obesity and polycystic ovaries. It affects over 7 million women worldwide. The current strategy to treat this disorder is based on the use of drugs that provide symptomatic relief. Most of these, however, exhibit numerous side effects and are not able to ameliorate all the signs and symptoms of PCOS. As dysbiosis is considered as one of the prime underlying causes...
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