Rebecca M. Reynolds
British Heart Foundation
OffspringPsychiatryInternal medicineObstetricsEndocrinologyPsychologyFetusPediatricsType 2 diabetesPregnancyGestational diabetesBody mass indexGlucocorticoidPopulationGestationObesityDiabetes mellitusBirth weightMedicineBiology
342Publications
64H-index
8,919Citations
Publications 339
Newest
#1Herman Pontzer (Duke University)H-Index: 37
#2Yosuke Yamada (Kyoto University)H-Index: 25
Last. Ellen E. Blaak (UM: Maastricht University)H-Index: 76
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Total daily energy expenditure ("total expenditure") reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates ra...
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#1Emma C. Johns (Edin.: University of Edinburgh)H-Index: 4
#2Elizabeth A. Hill (Edin.: University of Edinburgh)H-Index: 2
Last. Rebecca M. Reynolds (Edin.: University of Edinburgh)H-Index: 64
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Study Objectives: To determine the prevalence of obstructive sleep apnea (OSA) in a cohort of women with class III obesity, and a comparator lean group, in the second and third trimesters of pregna...
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#1Marius Lahti-Pulkkinen (UH: University of Helsinki)H-Index: 13
#2Katri Räikkönen (UH: University of Helsinki)H-Index: 87
Last. Rebecca M. Reynolds (Edin.: University of Edinburgh)H-Index: 64
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Maternal obesity in pregnancy predicts offspring psychopathology risk in childhood but it remains unclear whether maternal obesity or underweight associate with adult offspring mental disorders. We examined longitudinally whether maternal body mass index (BMI) in pregnancy predicted mental disorders in her offspring and whether the associations differed by offspring birth year among 68,571 mother-child dyads of Aberdeen Maternity and Neonatal Databank, Scotland. The offspring were born 1950-1999...
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#1Jemina Kivelä (UH: University of Helsinki)H-Index: 1
#2Heidi Sormunen-Harju (UH: University of Helsinki)
Last. Marius Lahti-Pulkkinen (NIH: National Institutes of Health)H-Index: 13
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CONTEXT Comprehensive assessment of metabolism in maternal obesity and pregnancy disorders can provide information about the shared maternal-fetal milieu and give insight into both maternal long-term health and intergenerational transmission of disease burden. OBJECTIVE To assess levels, profiles and change in the levels of metabolic measures during pregnancies complicated by obesity, gestational diabetes (GDM) or hypertensive disorders. DESIGN, SETTING AND PARTICIPANTS A secondary analysis of t...
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#1Carlos Sánchez-Soriano (Edin.: University of Edinburgh)H-Index: 2
#2Ewan R. Pearson (Dund.: University of Dundee)H-Index: 58
Last. Rebecca M. Reynolds (Edin.: University of Edinburgh)H-Index: 64
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Disturbances affecting early development have broad repercussions on the individual's health during infancy and adulthood. Multiple observational studies throughout the years have shown that alterations of fetal growth are associated with increased cardiometabolic disease risks. However, the genetic component of this association only started to be investigated in the last 40 years, when single genes with distinct effects were investigated. Birth weight (BW), commonly reported as the outcome of d...
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#1Lorna Ginnell (Edin.: University of Edinburgh)H-Index: 2
#2James P. Boardman (Edin.: University of Edinburgh)H-Index: 36
Last. Sue Fletcher-Watson (Edin.: University of Edinburgh)H-Index: 22
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#1Liu Yang (Edin.: University of Edinburgh)H-Index: 1
#2Lauren Lacey (Warw.: University of Warwick)H-Index: 4
Last. Rebecca M. Reynolds (Edin.: University of Edinburgh)H-Index: 64
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Metformin is widely used in pregnancy, despite lack of long-term safety for children. We hypothesised that metformin exposure in utero is associated with increased cardiovascular risk. We tested this hypothesis in a follow-up study of children born to obese mothers who had participated in a randomised controlled trial of metformin versus placebo in pregnancy (EMPOWaR). We measured body composition, peripheral blood pressure (BP), arterial pulse wave velocity and central haemodynamics (central BP...
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#2James P. BoardmanH-Index: 36
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