Pierluigi Bonomo
University of Florence
CancerInternal medicineRadiologySurgeryOncologyMedical physicsHead and neck cancerCyberknifeChemotherapyHead and neck squamous-cell carcinomaChemoradiotherapyDiseaseProstate cancerRadiosurgeryRe-IrradiationToxicityNuclear medicineHead and neckMultivariate analysisRadiation therapyBreast cancerMedicine
Publications 168
#1Pierluigi Bonomo (UniFI: University of Florence)H-Index: 20
#2G. Stocchi (UniFI: University of Florence)H-Index: 2
Last. Giuseppe SpinelliH-Index: 12
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PURPOSE In head and neck squamous cell carcinoma (HNSCC), the potential mitigating effect of complementary medicine interventions such as acupuncture for radiation-induced toxicity is unknown. This study aimed to assess the impact of acupuncture on the incidence and degree of severity of common radiation-induced side effects. METHODS In accordance with pre-specified PICO criteria, a systematic review was performed. Two electronic databases (Medline and Embase) were searched over a 10-year time f...
#1Susanne Singer (University of Mainz)H-Index: 43
#2Eva Hammerlid (Sahlgrenska University Hospital)H-Index: 34
Last. Amy Fullerton (JU: Jacksonville University)H-Index: 3
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PURPOSE The aim of this study was to explore what methods should be used to determine the minimal important difference (MID) and minimal important change (MIC) in scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43. METHODS In an international multi-centre study, patients with head and neck cancer completed the EORTC QLQ-HN43 before the onset of treatment (t1), three months after baseline (t2), and six months after baseline (t...
#1Pierluigi Bonomo (UniFI: University of Florence)H-Index: 20
#2Ester OrlandiH-Index: 22
Last. Paolo Bossi (University of Brescia)H-Index: 39
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#1Pierluigi BonomoH-Index: 20
#2Isacco DesideriH-Index: 17
Last. Lorenzo LiviH-Index: 28
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Background. Radiation-induced toxicity represents a crucial concern in oncological treatments of patients affected by head and neck neoplasms, due to its impact on survivors’ quality of life. Published reports suggested the potential of radiomics combined with machine learning methods in the prediction and assessment of radiation-induced toxicities, supporting a tailored radiation treatment management. In this paper, we present an update of the current knowledge concerning these modern approache...
#1Francesca De Felice (Sapienza University of Rome)H-Index: 21
#2Liliana Belgioia (UniGe: University of Genoa)H-Index: 11
Last. Stefano Arcangeli (University of Milan)H-Index: 24
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Abstract Purpose To evaluate efficacy and toxicity of weekly cisplatin chemoradiotherapy versus three-weekly cisplatin chemoradiotherapy and identify differences in clinical outcomes and severe toxicity rate. Methods PICOS/PRISMA methods were used to identify studies on PubMed, EMBASE and Cochrane Library, 2005–2019. Results Six randomized clinical trials (554 patients) were identified. Weekly cisplatin was not associated with significant overall survival (HR 1.13, 95 % CI 0.84–1.51) and progres...
#1Isacco Desideri (UniFI: University of Florence)H-Index: 17
#2Carlotta Becherini (UniFI: University of Florence)H-Index: 9
Last. Pierluigi Bonomo (UniFI: University of Florence)H-Index: 20
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Locally advanced Head and neck squamous cell carcinoma (SCCHN) represents a common oncologic pathology in older adults (OA). While radiotherapy represents a cornerstone in this context, it is unclear what is the optimal radiation regimen for SCCHN in the palliative setting, especially for OA. This article addresses issues related to palliative radiotherapy (PRT) in this setting with a focus on treatment modalities and toxicity. We also explore the use of quality of life and geriatric assessment ...
#1Giulio Francolini (UniFI: University of Florence)H-Index: 13
#2Isacco Desideri (UniFI: University of Florence)H-Index: 17
Last. Lorenzo Livi (UniFI: University of Florence)H-Index: 28
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BACKGROUND AND PURPOSE: COVID-19 constitutes a worldwide threat, prompting Italian Government to implement specific measures on March 8, 2020, to protect patients and health workers from disease transmission. The impact of preventive measures on daily activity of a radiotherapy facility may hamper the ability to fulfill normal workload burden. Thus, we assessed the number of delivered treatments in a specific observation period after the adoption of preventive measures (since March 11 to April 2...
#1Cosimo Nardi (UniFI: University of Florence)H-Index: 12
#2Maddalena Tomei (UniFI: University of Florence)H-Index: 1
Last. Stefano Colagrande (UniFI: University of Florence)H-Index: 24
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Abstract Background and Purpose Parotid lesions show overlaps of morphological findings, apparent diffusion coefficient (ADC) values and types of time/intensity curve. This research aimed to evaluate the role of diffusion weighted imaging texture analysis in differentiating between benign and malignant parotid lesions and in characterizing pleomorphic adenoma (PA), Warthin tumor (WT), epithelial malignancy (EM), and lymphoma (LY). Methods Texture analysis of 54 parotid lesions (19 PA, 14 WT, 14 ...
1 CitationsSource
#1Francesca De Felice (Sapienza University of Rome)H-Index: 21
#2E. D'AngeloH-Index: 6
Last. Ester OrlandiH-Index: 22
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The objective of the paper was to assess real-life experience in the management of head and neck cancer (HNC) patients during the COVID-19 pandemic in radiotherapy departments and to evaluate the variability in terms of adherence to American Society of Radiation Oncology (ASTRO) and European Society for Radiotherapy and Oncology (ESTRO) recommendations. In May 2020, an anonymous 30-question online survey, comparing acute phase of outbreak and pre-COVID-19 period, was conducted. Two sections expl...
4 CitationsSource