Vincent E de Meijer
University Medical Center Groningen
Internal medicineUrologyEndocrinologySurgeryPerfusionRetrospective cohort studyLiver diseaseFatty liverMachine perfusionLiver transplantationFish oilPancreatic cancerPopulationTransplantationMedicineParenteral nutritionGastroenterology
Publications 124
#1M.S. Walma (UvA: University of Amsterdam)H-Index: 1
#2Lilly J Brada (UvA: University of Amsterdam)H-Index: 2
Last. F. Daams (UvA: University of Amsterdam)H-Index: 5
view all 44 authors...
Abstract Introduction Since current studies on locally advanced pancreatic cancer (LAPC) mainly report from single, high-volume centers, it is unclear if outcomes can be translated to daily clinical practice. This study provides treatment strategies and clinical outcomes within a multicenter cohort of unselected patients with LAPC. Materials and methods Consecutive patients with LAPC according to Dutch Pancreatic Cancer Group criteria, were prospectively included in 14 centers from April 2015 un...
#1Rianne van Rijn (UMCG: University Medical Center Groningen)H-Index: 10
#2Ivo J. Schurink (UMCG: University Medical Center Groningen)H-Index: 1
Last. Robert J. Porte (UMCG: University Medical Center Groningen)H-Index: 83
view all 22 authors...
Abstract Background Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures. Hypothermic oxygenated machine ...
#1Shanice A. Karangwa (UMCG: University Medical Center Groningen)H-Index: 6
#2Jelle AdelmeijerH-Index: 27
Last. Marieke T. de BoerH-Index: 21
view all 10 authors...
BACKGROUND The specific effect of donation after circulatory death (DCD) liver grafts on fibrinolysis, blood loss, and transfusion requirements after graft reperfusion is not well known. The aim of this study was to determine whether transplantation of controlled DCD livers is associated with an elevated risk of hyper-fibrinolysis, increased blood loss and higher transfusion requirements upon graft reperfusion, compared to livers donated after brain death (DBD). METHODS A retrospective single-ce...
#1Natalia Smith-Cortinez (UMCG: University Medical Center Groningen)H-Index: 3
#2Raphael R. Fagundes (UMCG: University Medical Center Groningen)H-Index: 3
Last. Klaas Nico Faber (UMCG: University Medical Center Groningen)H-Index: 33
view all 13 authors...
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins, mainly composed of collagen. Hepatic stellate cells (HSCs) mediate liver fibrosis by secreting collagen. Vitamin C (ascorbic acid) is a cofactor of prolyl-hydroxylases that modify newly synthesized collagen on the route for secretion. Unlike most animals, humans cannot synthesize ascorbic acid and its role in liver fibrosis remains unclear. Here, we determined the effect of ascorbic acid and prolyl-hydroxylase ...
#1Stan BenjamensH-Index: 7
#2Vincent E de MeijerH-Index: 24
Last. Martijn P D HaringH-Index: 4
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The COVID-19 pandemic has vast global consequences. Yet, effective mitigation strategies and economic and medical outfall differ extensively across the globe. It is currently unclear how well researchers from all continents are represented in the unsolicited and solicited publications. A literature review was performed in SCOPUS on COVID-19 oriented publications in the four most impactful medical journals. These included the British Medical Journal, Journal of the American Medical Association, t...
#1Isabel M A Brüggenwirth (UMCG: University Medical Center Groningen)H-Index: 8
#2Marjolein van Reeven (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Robert J. Porte (UMCG: University Medical Center Groningen)H-Index: 83
view all 12 authors...
BACKGROUND: With the growing incidence of diabetes mellitus (DM), an increasing number of organ donors with DM can be expected. We sought to investigate the association between donor DM with early post-transplant outcomes. METHODS: From a national cohort of adult liver transplant recipients (1996-2016), all recipients transplanted with a liver from a DM donor (n=69) were matched 1:2 with recipients of livers from non-DM donors (n=138). The primary end-point included early post-transplant outcome...
#1Maureen J M WernerH-Index: 7
#2Vincent E de MeijerH-Index: 24
Last. Robert J. PorteH-Index: 83
view all 3 authors...
#1Ruben H J de KleineH-Index: 14
Last. Jan B F HulscherH-Index: 31
view all 4 authors...
#1Silke B. Bodewes (UMCG: University Medical Center Groningen)H-Index: 3
#2Otto B. van Leeuwen (UMCG: University Medical Center Groningen)H-Index: 10
Last. Robert J. Porte (UMCG: University Medical Center Groningen)H-Index: 83
view all 10 authors...
Oxygenated ex situ machine perfusion of donor livers is an alternative for static cold preservation that can be performed at temperatures from 0 °C to 37 °C. Organ metabolism depends on oxygen to produce adenosine triphosphate and temperatures below 37 °C reduce the metabolic rate and oxygen requirements. The transport and delivery of oxygen in machine perfusion are key determinants in preserving organ viability and cellular function. Oxygen delivery is more challenging than carbon dioxide remov...
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