Elizabeth Ladd
McGill University
Surface modificationvan der Waals forceNanotechnologyCationic polymerizationChemistryPolymer chemistryMaterials scienceMacromoleculeSiloxaneNanotubeCarboxylic acidDiolCycloadditionMaleimideHigh surfaceKey issuesMoleculePlatinumPolymerTinDendrimerClick chemistryCrystallographySupramolecular chemistry
4Publications
2H-index
50Citations
Publications 3
Newest
#1Elizabeth Ladd (McGill University)H-Index: 2
#2Amir Sheikhi (McGill University)H-Index: 18
Last. Ashok K. Kakkar (McGill University)H-Index: 43
view all 5 authors...
We report a versatile divergent methodology to construct dendrimers from a tetrafunctional core, utilizing the robust copper(I) catalyzed alkyne-azide cycloaddition (CuAAC, “click”) reaction for both dendrimer synthesis and post-synthesis functionalization. Dendrimers of generations 1–3 with 8–32 protected or free OH and acetylene surface groups, were synthesized using building blocks that included acetylene- or azide-terminated molecules with carboxylic acid or diol end groups, respectively. Th...
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#1Annie Castonguay (McGill University)H-Index: 17
#2Elizabeth Ladd (McGill University)H-Index: 2
Last. Ashok K. Kakkar (McGill University)H-Index: 43
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Hyperbranched and monodisperse macromolecules of nanodimensions, commonly referred to as dendrimers, have offered significant potential in addressing key issues in biology. In addition, their monodisperse nature and a generally described globular architecture with high surface group density, make them very coveted candidates as antimicrobial agents. Here, we provide an overview of what has been accomplished in exploring the potential of dendrimers as bactericides, as well as an analysis of the f...
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#1Michael A. Whitehead (McGill University)H-Index: 15
#2Ashok K. Kakkar (McGill University)H-Index: 43
Last. Thomas D. Lazzara (GAU: University of Göttingen)H-Index: 13
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Geometric characterization of two 1,3,5-triethynylbenzene (TEB) based dendrimers containing tin and platinum linking agents, and a 3,5- dihydroxybenzylalcohol (DHBA) based dendrimer containing a siloxane linking used the Semi-Empirical (PM3) Molecular Orbital Method and the Density Functional Theory Method (DFT). The theoretical results showed the increased rigidity of the backbone going from DHBA Silicon, Si, structure to TEB Tin, Sn, structure to TEB Platinum, Pt, dendrimer makes the dendrimer...
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