Juliëtte A. Severin
Erasmus University Rotterdam
EpidemiologyDrug resistanceOutbreakInternal medicineVirologyInfection controlCarbapenemMethicillin-resistant Staphylococcus aureusKlebsiella pneumoniaePseudomonas aeruginosaStaphylococcus aureusPopulationIntensive careCarriageAntibioticsMedicineMultilocus sequence typingBiologyMicrobiologyAntibiotic resistance
68Publications
18H-index
1,350Citations
Publications 68
Newest
#1C.P. Haanappel (EUR: Erasmus University Rotterdam)
#2A.F. Voor in ’t holt (EUR: Erasmus University Rotterdam)H-Index: 1
Last. Margreet C. Vos (EUR: Erasmus University Rotterdam)H-Index: 39
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#1Yulia Rosa Saharman (UI: University of Indonesia)H-Index: 5
#2Anis Karuniawati (UI: University of Indonesia)H-Index: 8
Last. Juliëtte A. Severin (EUR: Erasmus University Rotterdam)H-Index: 18
view all 7 authors...
Abstract Purpose To evaluate a low-cost multimodal intervention on the acquisition of carbapenem-non-susceptible Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa by patients in low-resource intensive care units. Materials and methods We performed a quasi-experimental study in a referral hospital in Jakarta, Indonesia: pre-intervention phase 1 (2013–2014), intervention phase 2 (2014–2015) and post-intervention phase 3 (2015–2016). The intervention was hand hygiene promot...
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#1M.D. van Dijk (EUR: Erasmus University Rotterdam)
#1Manon D. van Dijk (EUR: Erasmus University Rotterdam)H-Index: 1
Last. Margreet C. Vos (EUR: Erasmus University Rotterdam)H-Index: 39
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Summary Background Isolation precautions are recommended when caring for patients identified with highly resistant microorganisms (HRMO). However, the direct costs of patients in isolation are largely unknown. Aim To obtain detailed information on the daily direct costs associated with isolating patients identified with HRMO. Methods This study was performed from November until December 2017 on a twelve-bed surgical ward. This ward contained solely isolation rooms with anterooms. The daily direc...
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#1Yulia Rosa Saharman (UI: University of Indonesia)H-Index: 5
#2Anis Karuniawati (UI: University of Indonesia)H-Index: 8
Last. Henri A. Verbrugh (EUR: Erasmus University Rotterdam)H-Index: 83
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BACKGROUND Intensive care units (ICUs) in lower-middle income countries (LMICs) are suspected to constitute a special risk for patients of acquiring infection due to multiple antibiotic resistant organisms. The aim of this systematic scoping review was to present the data published on ICU-acquired infections and on antimicrobial resistance observed in ICUs in LMICs over a 13-year period. A systematic scoping review was conducted according to the PRISMA extension guideline for scoping reviews and...
3 CitationsSource
#1Manon D. van Dijk (EUR: Erasmus University Rotterdam)H-Index: 1
#2Diana van Netten (EUR: Erasmus University Rotterdam)H-Index: 1
Last. Margreet C. Vos (EUR: Erasmus University Rotterdam)H-Index: 39
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Background A rapid influx of large numbers of COVID-19 patients had to be handled by hospitals worldwide while specific infection prevention policies were not fully developed yet. This and other factors forced many hospitals to decide to cohort patients with COVID-19, expecting to minimize usage of personal protective equipment (PPE). Aim To investigate whether cohorting or isolation in single-patient rooms saves PPE. Highlight the advantages and disadvantages of organizing patient care in cohor...
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#1Maarten J. Sarink (EUR: Erasmus University Rotterdam)H-Index: 2
#2J. Pirzadian (EUR: Erasmus University Rotterdam)
Last. J.J. van Hellemond (EUR: Erasmus University Rotterdam)H-Index: 3
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Summary Verona-Integron-encoded-Metallo-β-lactamase-positive Pseudomonas aeruginosa (VIM-PA) is a cause of hard-to-treat nosocomial infections, and can colonize hospital water networks alongside Acanthamoeba. We developed an in vitro disinfection model to examine whether Acanthamoeba castellanii can harbour VIM-PA intracellularly, allowing VIM-PA to evade being killed by currently-used hospital disinfectants. We observed that A. castellanii presence resulted in significantly increased survival o...
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#1Jannette Pirzadian (EUR: Erasmus University Rotterdam)H-Index: 1
#2Susan P Harteveld (EUR: Erasmus University Rotterdam)H-Index: 1
Last. Juliëtte A. Severin (EUR: Erasmus University Rotterdam)H-Index: 18
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In hospitals, Verona Integron-encoded Metallo-beta-lactamase (VIM)-positive Pseudomonas aeruginosa may colonize sink drains, and from there, be transmitted to patients. These hidden reservoirs are difficult to eradicate since P. aeruginosa forms biofilms that resist disinfection. However, little is known on the composition of these biofilms. Therefore, culturomics was used for the first time to investigate the viable microbiota in four hospital sink drain samples with longstanding VIM-positive P...
1 CitationsSource
Background: Studies have shown that patients colonized with highly resistant microorganisms (HRMO) contaminate the hospital environment, and that transmission from contaminated environments to patients occurs. In May 2018, the Erasmus MC University Medical Center, Rotterdam, moved from a hospital with mostly multiple-occupancy rooms to a new hospital with 100% single-patient rooms with private bathrooms. This move provided the unique opportunity to determine environmental contamination before th...
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#1Andreu Coello Pelegrin (BioMérieux)H-Index: 4
#2Yulia Rosa Saharman (UI: University of Indonesia)H-Index: 5
Last. Juliëtte A. Severin (EUR: Erasmus University Rotterdam)H-Index: 18
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Volume 10, no. 6, e02384-19, 2019, [https://doi.org/10.1128/mBio.02384-19][1]. On PDF page 1, in the abstract, in the sentence “Four high-risk international CNPA clones (ST235, ST823, ST375, and ST446) dominated, but the distribution of these clones changed significantly after the intervention was
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