Alexander C. Egbe
Mayo Clinic
Internal medicineSurgeryCardiologyRetrospective cohort studyHemodynamicsHazard ratioHeart failureTetralogy of FallotVentricleAtrial fibrillationAortaHeart diseasePulmonary arteryPopulationIn patientIncidence (epidemiology)DiastoleMedicineCohortEjection fractionBlood pressure
187Publications
20H-index
1,417Citations
Publications 187
Newest
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2William R. Miranda (Mayo Clinic)H-Index: 14
Last. Heidi M. Connolly (Mayo Clinic)H-Index: 75
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AIMS The prognostic implication of left atrial (LA) dysfunction and left ventricular diastolic dysfunction (LVDD) in patients with coarctation of aorta (COA) is unknown. The purpose of this study was to determine whether LA dysfunction and LVDD were associated with mortality in COA patients. METHODS AND RESULTS This is a retrospective review of adults (age ≥18 years) with repaired COA that underwent transthoracic echocardiogram (2000-18). LVDD was determined using the 2016 guidelines for LV dias...
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#1Ahmed Krimly (King Saud bin Abdulaziz University for Health Sciences)H-Index: 1
#2C. Charles Jain (Mayo Clinic)H-Index: 4
Last. Gruschen R. Veldtman (Jubilee Hospital)H-Index: 33
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Fontan palliation represents one of the most remarkable surgical advances in the management of individuals born with functionally univentricular physiology. The operation secures adult survival for all but a few with unfavourable anatomy and/or physiology. Inherent to the physiology is passive transpulmonary blood flow, which produces a vulnerability to adequate filling of the systemic ventricle at rest and during exertion. Similarly, the upstream effects of passive flow in the lungs are venous ...
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#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2William R. Miranda (Mayo Clinic)H-Index: 14
Last. Iftikhar J. Kullo (Mayo Clinic)H-Index: 58
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Abstract The purpose of the study was to determine which out-of-office BP measurement modality has the best correlation with central aortic systolic BP, arterial stiffness (a determinant of central aortic pressure) and LV mass index (LVMI) which represents LV adaptation to elevated central aortic pressures. In this prospective study, we demonstrated that 24h ambulatory systolic BP has better correlation with central aortic systolic BP (arterial load) and LVMI as compared to home systolic BP. 24h...
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#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2William R. Miranda (Mayo Clinic)H-Index: 14
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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BACKGROUND Brachial systolic blood pressure (BP) is the most commonly used metric for monitoring hypertension. However, recent studies suggest that brachial systolic BP underestimates left ventricle (LV) systolic load in patients with coarctation of aorta (COA). Since brachial systolic BP is used as a surrogate of arterial afterload in clinical practice, it is important to determine how well it correlates with LV remodeling and stiffness in patients with COA as compared to patients with idiopath...
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#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2William R. Miranda (Mayo Clinic)H-Index: 14
Last. Joseph A. Dearani (Mayo Clinic)H-Index: 95
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Background Although tricuspid valve surgery improves functional capacity in patients with Ebstein anomaly, it is not always associated with improvement in aerobic capacity. The purpose of this study was to identify the determinants of improved aerobic capacity after tricuspid valve surgery in adults with Ebstein anomaly with severe tricuspid regurgitation. Methods Retrospective study of patients with severe tricuspid regurgitation due to Ebstein anomaly that had tricuspid valve surgery at Mayo C...
1 CitationsSource
#1Vinayak Kumar (Mayo Clinic)H-Index: 3
#2Armando Manduca (Mayo Clinic)H-Index: 59
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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BACKGROUND Myocardial volume is assumed to be constant over the cardiac cycle in the echocardiographic models used by professional guidelines, despite evidence that suggests otherwise. The aim of this paper is to use literature-derived myocardial strain values from healthy patients to determine if myocardial volume changes during the cardiac cycle. METHODS A systematic review for studies with longitudinal, radial, and circumferential strain from echocardiography in healthy volunteers ultimately ...
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#1Jwan A Naser (Mayo Clinic)H-Index: 1
#2Ioana Petrescu (Mayo Clinic)H-Index: 4
Last. Sorin V. Pislaru (Mayo Clinic)H-Index: 36
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Objective Bioprosthetic valve thrombosis (BPVT) is increasingly recognised as a major cause of prosthetic dysfunction in the first years postimplantation. How early abnormal gradients can be detected prior to diagnosis and how fast they normalise with anticoagulant therapy is unknown. We set forth to (1) evaluate patterns of increase in gradients prior to BPVT diagnosis and (2) characterise time-course of response to anticoagulation. Methods Patients treated with warfarin for BPVT (1999–2019) wi...
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#1William R. Miranda (Mayo Clinic)H-Index: 14
#2Alexander C. Egbe (Mayo Clinic)H-Index: 20
Last. Heidi M. Connolly (Mayo Clinic)H-Index: 75
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Abstract Background Data on the features of double-chambered right ventricular (DCRV) in adults are limited. It is also unclear how invasive and Doppler-derived assessments of right ventricular (RV) obstruction in DCRV correlate. Methods Retrospective review of 17 adults (age ≥18 years) diagnosed with DCRV who underwent right heart catheterization at Mayo Clinic, MN between 1990 and 2021. Clinical, echocardiographic, and invasive hemodynamics were abstracted from the medical charts. Results Mean...
1 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2William R. Miranda (Mayo Clinic)H-Index: 14
Last. Heidi M. Connolly (Mayo Clinic)H-Index: 75
view all 7 authors...
The purpose of this study was to describe procedural outcomes, hemodynamic improvement, regression of left ventricular (LV) mass hypertrophy, and cardiovascular. The primary outcomes were procedural complications, reinterventions, and hemodynamic improvement after coarctation of aorta (COA) repair. The secondary outcomes were improvement in the severity of hypertension, regression of LV mass index, and incidence of cardiovascular events (atrial fibrillation, ventricular tachycardia, heart failur...
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#1C. Charles Jain (Mayo Clinic)H-Index: 4
#2David R. Holmes (Mayo Clinic)H-Index: 192
Last. William R. Miranda (Mayo Clinic)H-Index: 14
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