Andrea Mari
National Research Council
PhysicsInternal medicineEndocrinologyCarbohydrate metabolismChemistryType 2 diabetesInsulin resistancePostprandialGlucagonGlucose clamp techniqueIncretinInsulinPancreatic hormoneImpaired glucose toleranceGlucose tolerance testInsulin sensitivityDiabetes mellitusQuantum mechanicsMedicineQuantumBiology
Publications 256
#1Andrea MariH-Index: 67
#2Nathan ShammahH-Index: 7
Last. William ZengH-Index: 10
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We propose a general framework for quantum error mitigation that combines and generalizes two techniques: probabilistic error cancellation (PEC) and zero-noise extrapolation (ZNE). Similarly to PEC, the proposed method represents ideal operations as linear combinations of noisy operations that are implementable on hardware. However, instead of assuming a fixed level of hardware noise, we extend the set of implementable operations by noise scaling. By construction, this method encompasses both PE...
2 Citations
#2Donato FarinaH-Index: 6
Last. V. GiovannettiH-Index: 5
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#1Ruth L. M. Cordiner (Dund.: University of Dundee)H-Index: 1
#2Andrea Mari (National Research Council)H-Index: 67
Last. Ewan R. Pearson (Dund.: University of Dundee)H-Index: 58
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AIMS/HYPOTHESIS Studies in permanent neonatal diabetes suggest that sulphonylureas lower blood glucose without causing hypoglycaemia, in part by augmenting the incretin effect. This mechanism has not previously been attributed to sulphonylureas in patients with type 2 diabetes (T2DM). We therefore aimed to evaluate the impact of low dose gliclazide on beta-cell function and incretin action in patients with T2DM. METHODS Paired oral glucose tolerance tests and isoglycaemic infusions were performe...
#1Teresa Mezza (UCSC: Catholic University of the Sacred Heart)H-Index: 16
#2Pietro Manuel Ferraro (UCSC: Catholic University of the Sacred Heart)H-Index: 24
Last. Andrea Giaccari (UCSC: Catholic University of the Sacred Heart)H-Index: 32
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BACKGROUND The appearance of hyperglycemia is due to insulin resistance, functional deficits in the secretion of insulin and a reduction of β-cell mass. There is a long-standing debate as to the relative contribution of these factors to clinically manifest β-cell dysfunction. The aim of this study was to verify the effect of one of these factors, the reduction of β-cell mass, on the subsequent development of hyperglycemia. METHODS To pursue this aim, non-diabetic patients, scheduled for identica...
1 CitationsSource
#1Domenico TricòH-Index: 13
#2Diego MoriconiH-Index: 6
Last. Monica NannipieriH-Index: 30
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Low-calorie Mediterranean-style or low-carbohydrate dietary regimens are widely used nutritional strategies against obesity and associated metabolic diseases, including type 2 diabetes. The aim of this study was to compare the effectiveness of a balanced Mediterranean diet with a low-carbohydrate diet on weight loss and glucose homeostasis in morbidly obese individuals at high risk to develop diabetes. Insulin secretion, insulin clearance, and different β-cell function components were estimated ...
#1Maria Francesca Russo (UCSC: Catholic University of the Sacred Heart)H-Index: 1
#2Erminia Lembo (UCSC: Catholic University of the Sacred Heart)H-Index: 1
Last. Geltrude Mingrone (UCSC: Catholic University of the Sacred Heart)H-Index: 71
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CONTEXT Non-alcoholic steatohepatitis(NASH)is considered as the hepatic counterpart of the metabolic syndrome. OBJECTIVE To investigate the determinants of NASH reversal in patients undergoing biliopancreatic diversion(BPD)in a 5-year follow-up study. DESIGN Prospective Study, Policlinico Universitario Agostino Gemelli. PARTICIPANTS 37 patients underwent fine-needle liver biopsy during BPD. Nine of them had a negative liver biopsy for NASH and were excluded. Ultrasonography-guided percutaneous l...
#1Carla Colombo (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 54
#2Andrea Foppiani (University of Milan)H-Index: 7
Last. Alberto Battezzati (University of Milan)H-Index: 29
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PURPOSE The question whether the new cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs aimed at restoring CFTR protein function might improve glucose metabolism is gaining attention, but data on the effect of lumacaftor/ivacaftor treatment (LUMA/IVA) on glucose tolerance are limited. We evaluated the variation in glucose metabolism and insulin secretion in CF patients homozygous for Phe508del CFTR mutation after one-year treatment with LUMA/IVA in comparison to patients ...
2 CitationsSource
#1Andrea MariH-Index: 67
#1Andrea MariH-Index: 22
Last. Nathan KilloranH-Index: 21
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For a large class of variational quantum circuits, we show how arbitrary-order derivatives can be analytically evaluated in terms of simple parameter-shift rules, i.e., by running the same circuit with different shifts of the parameters. As particular cases, we obtain parameter-shift rules for the Hessian of an expectation value and for the metric tensor of a variational state, both of which can be efficiently used to analytically implement second-order optimization algorithms on a quantum compu...
27 CitationsSource