Eun Ha Lee
Kigali Institute of Science and Technology
Molecular biologyHigh-performance liquid chromatographyEnzymeChemistryApoptosisOxidative stressPhyllostachys nigraAldose reductaseAntioxidantTricinEthyl acetateLipid peroxidationABTSRetinal ganglionBlack bambooRecombinant DNAChromatographyNitric oxideBiochemistryTraditional medicineBiologyCell biologyPharmacology
44Publications
16H-index
989Citations
Publications 43
Newest
#1Kwang Hyun Cha (Kigali Institute of Science and Technology)H-Index: 15
#2Eun Ha Lee (Kigali Institute of Science and Technology)H-Index: 16
Last. Cheol-Ho Pan (Kigali Institute of Science and Technology)H-Index: 25
view all 10 authors...
Abstract We investigated the impact of a fermented milk product on gut microbiota and their metabolism in 3 different conditions of the colon with a systemic viewpoint. An in vitro semi-continuous anaerobic cultivation was used to assess the colon compartment-specific influence of fermented milk, followed by a multiomics approach combining 16S rDNA amplicon sequencing and nuclear magnetic resonance (NMR) spectroscopy. The microbiome profiling and metabolomic features were significantly different...
14 CitationsSource
#1Eun Ha Lee (Kigali Institute of Science and Technology)H-Index: 16
#2Kwang Hyun Cha (Kigali Institute of Science and Technology)H-Index: 15
Last. Cheol-Ho Pan (UST: Korea University of Science and Technology)H-Index: 25
view all 5 authors...
This study aimed to determine the bioaccessibility of lutein in lutein-rich food, using static and dynamic models of in vitro gastrointestinal digestion. Here, kale powder (KP) and lutein supplement (LS) were used as representative lutein-rich foods. The bioaccessibility of lutein from KP did not considerably differ between static (59.92%) and dynamic (56.08%) digestion. Bioaccessibility was consistently maintained at the same level during dynamic digestion. The amount of lutein released from th...
3 CitationsSource
#1Kyungsu Kang (KIST: Korea Institute of Science and Technology)H-Index: 18
#2Lei Peng (KIST: Korea Institute of Science and Technology)H-Index: 1
Last. Yong-Soo Choi (KIST: Korea Institute of Science and Technology)H-Index: 13
view all 10 authors...
Objectives To develop a high-throughput screening system to measure the conversion of testosterone to dihydrotestosterone (DHT) in cultured human prostate cancer cells using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS).
1 CitationsSource
#1Chang Gun Lee (College of Health Sciences, Bahrain)H-Index: 6
#2Eun Ha Lee (KIST: Korea Institute of Science and Technology)H-Index: 16
Last. Ki Jong Rhee (College of Health Sciences, Bahrain)H-Index: 19
view all 5 authors...
Abstract Here, we report animal experimental data associated with the article entitled “AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo“ (Jung et al., 2017) [1] . We tested the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin hydrochloride in a nude mouse xenograft model of A549 human lung cancer cells. In our experiment, Selaginella tamarisci...
6 CitationsSource
#1Yu-Jin Jung (KIST: Korea Institute of Science and Technology)H-Index: 7
#2Eun Ha Lee (KIST: Korea Institute of Science and Technology)H-Index: 16
Last. Kyungsu Kang (KIST: Korea Institute of Science and Technology)H-Index: 18
view all 8 authors...
Abstract Ethnopharmacological relevance Selaginella tamariscina (P.Beauv.) Spring is a traditional medicinal plant used to treat various human diseases, including cancer, in Asia. The detailed molecular mechanism underlying the anti-cancer effects of this plant and the anti-cancer action of the combinatorial treatment of S. tamariscina and doxorubicin have not yet been investigated. Aim of the study We evaluated the inhibitory activity of S. tamariscina extract (STE) and its major compound, amen...
24 CitationsSource
#1Raphaël S. Daveau (UCPH: University of Copenhagen)H-Index: 5
#2Krishna C. BalramH-Index: 15
Last. Peter Lodahl (UCPH: University of Copenhagen)H-Index: 51
view all 13 authors...
Many photonic quantum information processing applications would benefit from a high brightness, fiber-coupled source of triggered single photons. Here, we present a fiber-coupled photonic-crystal waveguide (PCWG) single-photon source relying on evanescent coupling of the light field from a tapered outcoupler to an optical fiber. A two-step approach is taken where the performance of the tapered outcoupler is recorded first on an independent device containing an on-chip reflector. Reflection measu...
78 CitationsSource
#1Erdenedolgor Erdene-Ochir (UST: Korea University of Science and Technology)H-Index: 4
#2Bok-Kyu Shin (Kigali Institute of Science and Technology)H-Index: 3
Last. Cheol-Ho Pan (UST: Korea University of Science and Technology)H-Index: 25
view all 9 authors...
Phaeodactylum tricornutum is a model diatom, and its genomic sequence data and expressed sequence tag databases are available. This study was to discover a new endogenous promoter that drives strong constitutive expression of a protein of interest in P. tricornutum. To find promoter candidates, the intracellular proteins of P. tricornutum grown to stationary phase were extracted and identified by LC–MS/MS. Glutamine synthetase (GLNA) was one of the most abundantly expressed proteins during the s...
9 CitationsSource
#1Ya-Fang ShangH-Index: 1
#2Kwang Hyun ChaH-Index: 15
Last. Byung Hun Um (UST: Korea University of Science and Technology)H-Index: 1
view all 5 authors...
Introduction: Bamboo and black bamboo leaves have long been used as folk remedies for the treatment of hypertension, cardiovascular disease in oriental regions. Many studies have shown that bamboo leaves extract and its main phenolic compounds have antioxidant activity before bio accessibility assessment. Methods: The optimized extraction methods for biological compound tricin by pressuriz ed liquid extraction (PLE) from black bamboo leaves were studied and tricin abundant black bamboo extracts ...
9 CitationsSource
#1Eun Ok Kim (KIST: Korea Institute of Science and Technology)H-Index: 7
#2Kwang Hyun ChaH-Index: 15
Last. Byung-Hun UmH-Index: 27
view all 7 authors...
This study aims to investigate the bioavailability of ginsenosides during simulated digestion of white (WG) and red (RG) ginseng powders. Stability, bioaccessibility, and permeability of ginsenosides present in WG and RG were studied in a Caco-2 cell culture model coupled with oral, gastric, and small intestinal simulated digestion. Most ginsenosides in WG and RG were stable (>90%) during the simulated digestion. Bioaccessibilities of total ginsenosides during in vitro digestion of WG and RG wer...
15 CitationsSource
#1Dae-Geun Song (KIST: Korea Institute of Science and Technology)H-Index: 16
#2Kyungsu Kang (KIST: Korea Institute of Science and Technology)H-Index: 18
Last. Chu Won Nho (KIST: Korea Institute of Science and Technology)H-Index: 25
view all 6 authors...
Gymnasterkoreayne B (GKB) is a natural polyacetylene isolated from Gymnaster koraiensis. The antiproliferative activity of GKB has been reported in various human cancer cells but its mechanism is s...
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