Pascal Probst
University Hospital Heidelberg
Internal medicineSurgeryOdds ratioRandomized controlled trialPhysical therapyClinical endpointCochrane LibraryPancreaticoduodenectomyMEDLINEAbdominal surgeryPancreatic surgeryGastric emptyingPerioperativeConfidence intervalClinical trialMalnutritionGeneral surgeryMedicineComplicationMeta-analysis
Publications 126
#1Kerstin Wohlleber (Heidelberg University)
#2Patrick Heger (Heidelberg University)H-Index: 8
Last. André L. Mihaljevic (Heidelberg University)H-Index: 20
view all 6 authors...
Purpose null Patient-reported outcomes including health-related quality of life (HRQoL) are important oncological outcome measures. The validation of HRQoL instruments for patients with hepatocellular and cholangiocellular carcinoma is lacking. Furthermore, studies comparing different treatment options in respect to HRQoL are sparse. The objective of the systematic review and meta-analysis was, therefore, to identify all available HRQoL tools regarding primary liver cancer, to assess the methodo...
#1Rosa Klotz (Heidelberg University)H-Index: 3
#2Thilo Hackert (Heidelberg University)H-Index: 57
Last. Beat P. Müller-Stich (Heidelberg University)H-Index: 33
view all 14 authors...
Abstract null null Background null Surgical resection is the mainstay of potential cure for patients with pancreatic cancer, however, local recurrence is frequent. Previously, we have described an extended resection technique for pancreatoduodenectomy aiming at a radical resection of the nerve and lymphatic tissue between celiac artery, superior mesenteric artery and mesenteric-portal axis (TRIANGLE operation). Until now, data on postoperative outcome have not been reported, yet. null null null ...
#1Anastasia Murtha-Lemekhova (Heidelberg University)
#2Juri Fuchs (Heidelberg University)H-Index: 2
Last. Katrin Hoffmann (Heidelberg University)H-Index: 23
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Abstract null null Background null Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has expanded and spearheaded development in hepatobiliary surgery. Monosegment-ALPPS tests liver regeneration limits and may present as the last feasible curative treatment option. null null null Methods null Electronic databases (MEDLINE, Web of Science, Google Scholar, Cochrane Library and WHO International Clinical Trials Registry Platform) were searched for publications on m...
The pathophysiology of post-hepatectomy liver failure is not entirely understood but is rooted in the disruption of normal hepatocyte regeneration and homeostasis. Current investigations of post-hepatectomy liver failure and regeneration are focused on evaluation of circulating hepatic function parameters (transaminases, cholestasis, and coagulation parameters), volumetry and hepatic hemodynamics. However, identification of biochemical factors associated with regeneration and post hepatectomy li...
#1Pascal Probst (Heidelberg University)H-Index: 22
#2Felix J Hüttner (Heidelberg University)H-Index: 16
Last. Marco Del Chiaro (Anschutz Medical Campus)H-Index: 31
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BACKGROUND Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery. METHODS PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all...
#1David J BeardH-Index: 64
#2Marion K CampbellH-Index: 70
Last. Jonathan PughH-Index: 9
view all 31 authors...
#1Eva Kalkum (German Society of Surgery)H-Index: 5
#1Eva Kalkum (German Society of Surgery)
Last. Pascal Probst (German Society of Surgery)H-Index: 22
view all 10 authors...
Systematic reviews are an important tool of evidence-based surgery. Surgical systematic reviews and trials, however, require a special methodological approach. This article provides recommendations for conducting state-of-the-art systematic reviews in surgery with or without meta-analysis. For systematic reviews in surgery, MEDLINE (via PubMed), Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL) should be searched. Critical appraisal is at the core of every surgical sys...
#1Mohammad Al-Saeedi (Heidelberg University)
#2Ali Ramouz (Heidelberg University)H-Index: 4
Last. Arianeb Mehrabi (Heidelberg University)H-Index: 33
view all 12 authors...
Background In patients with hepatic cystic echinococcosis (CE), treatment effectiveness, outcomes, complications, and recurrence rate are controversial. Endocystectomy is a conservative surgical approach that adequately removes cyst contents without loss of parenchyma. This conservative procedure has been modified in several ways to prevent complications and to improve surgical outcomes. This systematic review aimed to evaluate the intraoperative and postoperative complications of endocysectomy ...