Rachel Forster
University of Edinburgh
Quality of lifeOphthalmologyInternal medicineSurgeryLogistic regressionOdds ratioTortuosityProspective cohort studyPlaceboPatient satisfactionAmputationPulmonary embolismEndovascular aneurysm repairType 2 diabetesAortic aneurysmAortic ruptureDeep veinVenous thrombosisAbdominal surgeryRetinalSurgical repairMyocardial infarctionStrokeClinical trialMedicineRelative riskMeta-analysis
Publications 13
#1Alistair L. Carr (Edin.: University of Edinburgh)
#2Anniek J. Sluiman (Edin.: University of Edinburgh)H-Index: 1
Last. Jackie F. Price (Edin.: University of Edinburgh)H-Index: 4
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Aims/hypothesis We aimed to determine the association of depression with dementia risk in people with type 2 diabetes, and to explore the possible mediating role of inflammation in this relationship. Methods The Edinburgh Type 2 Diabetes Study is a prospective cohort of 1066 men and women with type 2 diabetes aged 60-75 years. Cox proportional hazards regression analysis was used to investigate the association between depression, assessed at baseline, and subsequent risk of dementia over 10 year...
#1Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
#2Emmanuel Sandoval Garcia (Edin.: University of Edinburgh)H-Index: 1
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AIMS/HYPOTHESIS Our aim was to determine whether a range of prespecified retinal vessel traits were associated with incident diabetic retinopathy in adults with type 2 diabetes. METHODS In the prospective observational cohort Edinburgh Type 2 Diabetes Study of 1066 adults with type 2 diabetes, aged 60-75 years at recruitment, 718 were free from diabetic retinopathy at baseline. Baseline retinal traits including vessel widths, tortuosity (curvature) and fractal dimensions (network complexity), we...
2 CitationsSource
#1Muthu Rama Krishnan Mookiah (Dund.: University of Dundee)H-Index: 19
#2Sarah McGrory (Edin.: University of Edinburgh)H-Index: 9
Last. Emanuele Trucco (Dund.: University of Dundee)H-Index: 43
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Within the general framework of consistent and reproducible morphometric measurements of the retinal vasculature in fundus images, we present a quantitative pilot study of the changes in measurements commonly used in retinal biomarker studies (e.g. caliber-related, tortuosity and fractal dimension of the vascular network) induced by centering fundus image acquisition on either the optic disc or on the macula. To our best knowledge, no such study has been reported so far. Analyzing 149 parameters...
6 CitationsSource
#1Stephen A. Badger (Mater Misericordiae University Hospital)H-Index: 4
#2Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
Last. Denis W. Harkin (Royal Victoria Regional Health Centre)H-Index: 21
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Background An abdominal aortic aneurysm (AAA) (pathological enlargement of the aorta) is a condition that can occur as a person ages. It is most commonly seen in men older than 65 years of age. Progressive aneurysm enlargement can lead to rupture and massive internal bleeding, which is fatal unless timely repair can be achieved. Despite improvements in perioperative care, mortality remains high (approximately 50%) after conventional open surgical repair. Endovascular aneurysm repair (EVAR), a mi...
125 CitationsSource
#1Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
#2Marlene C. W. Stewart (Edin.: University of Edinburgh)H-Index: 20
Background The optimal duration of thromboprophylaxis after total hip or knee replacement, or hip fracture repair remains controversial. It is common practice to administer prophylaxis using low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) until discharge from hospital, usually seven to 14 days after surgery. International guidelines recommend extending thromboprophylaxis for up to 35 days following major orthopaedic surgery but the recommendation is weak due to moderate quali...
46 CitationsSource
#1Stephen A. Badger (Mater Misericordiae University Hospital)H-Index: 4
#2Denis W. HarkinH-Index: 21
Last. Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
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Objectives Emergency endovascular aneurysm repair (eEVAR) may improve outcomes for patients with ruptured abdominal aortic aneurysm (RAAA). The study aim was to compare the outcomes for eEVAR with conventional open surgical repair for the treatment of RAAA. Setting A systematic review of relevant publications was performed. Randomised controlled trials (RCTs) comparing eEVAR with open surgical repair for RAAA were included. Participants 3 RCTs were included, with a total of 761 patients with RAA...
36 CitationsSource
#1Kareem SalhiyyahH-Index: 5
#2Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
Last. Jonathan Michaels (University of Sheffield)H-Index: 33
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BACKGROUND: Intermittent claudication (IC) is a symptom of peripheral arterial disease (PAD) and is associated with high morbidity and mortality. Pentoxifylline, one of many drugs used to treat IC, acts by decreasing blood viscosity, improving erythrocyte flexibility and promoting microcirculatory flow and tissue oxygen concentration. Many studies have evaluated the efficacy of pentoxifylline in treating individuals with PAD, but results of these studies are variable. This is an update of a revi...
63 CitationsSource
#1Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
#2Fania Pagnamenta (Newcastle upon Tyne Hospitals NHS Foundation Trust)H-Index: 3
Background It is estimated that people in industrialised countries have a 1% chance of suffering from a leg ulcer at some time in their life. The majority of leg ulcers are associated with circulation problems; poor blood return in the veins causes venous ulcers (around 70% of ulcers) and poor blood supply to the legs causes arterial ulcers (around 22% of ulcers). Treatment of arterial leg ulcers is directed towards correcting the poor arterial blood supply, for example by correcting arterial bl...
15 CitationsSource
#1Raza Alikhan (University Hospital of Wales)H-Index: 14
#2Rachel Forster (Edin.: University of Edinburgh)H-Index: 8
Last. Alexander T. Cohen (King's College)H-Index: 59
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Background Venous thromboembolic disease has been extensively studied in surgical patients. The benefit of thromboprophylaxis is now generally accepted, but it is medical patients who make up the greater proportion of the hospital population. Medical patients differ from surgical patients with regard to their health and the pathogenesis of thromboembolism and the impact that preventative measures can have. The extensive experience from thromboprophylaxis studies in surgical patients is therefore...
89 CitationsSource