Tânia Melo
University of Aveiro
EndocrinologyMass spectrometryChemistryPolyunsaturated fatty acidAntioxidantLipid profilePhospholipidLipidomeLipid peroxidationPhosphatidylethanolamineLipid oxidationTandem mass spectrometryFood scienceChromatographyLipid metabolismFatty acidBiochemistryOxidative phosphorylationLipidomicsBiology
82Publications
15H-index
792Citations
Publications 82
Newest
#1Diana Lopes (University of Aveiro)H-Index: 7
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. M. Rosário M. Domingues (University of Aveiro)H-Index: 32
view all 10 authors...
Abstract The valorization of seaweeds has generated unprecedented interest in recent years due to their unique chemical characteristics. The taxonomic differentiation between Chlorophyta, Rhodophyta, and Ochrophyta is often supported by their contrasting chemical characteristics. Polar lipids are the most abundant class of lipids in several seaweeds species often labelled as valuable phytochemicals. Nevertheless, little is still known about how the polar lipidome of seaweeds varies within and am...
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#1João P. Monteiro (University of Aveiro)H-Index: 14
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. M. Rosário M. Domingues (University of Aveiro)H-Index: 32
view all 8 authors...
Abstract Macroalgae aquaculture is thriving, and kelps such as Saccharina latissima, are now farmed over different production sites across Europe. Macroalgae production in integrated multi-trophic aquaculture setups is gaining relevance due to increased biomass yield and bioremediation potential. Nevertheless, there is a substantiated need to understand how this type of production shapes biomass composition. The present study evaluated the influence of time of harvesting and proximity to nutrien...
1 CitationsSource
#1Sílvia Petronilho (University of Aveiro)H-Index: 7
#2Bruna Neves (University of Aveiro)H-Index: 2
Last. M. Rosário M. Domingues (University of Aveiro)H-Index: 32
view all 9 authors...
Frying allows cooking food while promoting their organoleptic properties, imparting crunchiness and flavor. The drawback is the oxidation of triacylglycerides (TAGs), leading to the formation of primary oxidized TAGs. Although they have been associated with chronic and degenerative diseases, they are precursors of pleasant flavors in fried foods. Nevertheless, there is a lack of knowledge about the oxidation species present in foods and their involvement in positive/negative health effects. In t...
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#1Daniela Couto (University of Aveiro)H-Index: 3
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. Pedro Domingues (University of Aveiro)H-Index: 37
view all 7 authors...
Abstract Chlorella growing under different conditions can adapt its biochemical composition and its fatty acid profile, but the alterations in polar lipids remain poorly explored. In this study, the polar lipidome of Chlorella vulgaris grown under autotrophic (C-Auto) and heterotrophic (C-Hetero) conditions were characterized using hydrophilic interaction liquid chromatography–electrospray ionization mass spectrometry and gas chromatography–mass spectrometry. A total of 173 and 167 lipid species...
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#1Tiago A. Conde (University of Aveiro)H-Index: 1
#2Daniela Couto (University of Aveiro)H-Index: 3
Last. Pedro Domingues (University of Aveiro)H-Index: 37
view all 7 authors...
There is a growing trend to explore microalgae as an alternative resource for the food, feed, pharmaceutical, cosmetic and fuel industry. Moreover, the polar lipidome of microalgae is interesting because of the reports of bioactive polar lipids which could foster new applications for microalgae. In this work, we identified for the first time the Chlorococcum amblystomatis lipidome using hydrophilic interaction liquid chromatography-high resolution electrospray ionization- tandem mass spectrometr...
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#1Christina Savva (KI: Karolinska Institutet)H-Index: 4
#2Luisa A. Helguero (University of Aveiro)H-Index: 26
Last. Marion Korach-André (KI: Karolinska Institutet)H-Index: 15
view all 11 authors...
The prevalence of overweight and obesity among children has drastically increased during the last decades and maternal obesity has been demonstrated as one of the ultimate factors. Nutrition-stimulated transgenerational epigenetic regulation of key metabolic genes is fundamental to the developmental origins of the metabolic syndrome. Fetal nutrition may differently influence female and male offspring. In this work, we investigated the sex-dependent programming of maternal obesity in visceral, su...
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#1Helena Ferreira (University of Aveiro)H-Index: 10
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. M. Rosário M. Domingues (University of Aveiro)H-Index: 32
view all 6 authors...
Abstract Multiple sclerosis is a neurodegenerative disease causing disability in young adults. Alterations in metabolism and lipid profile have been associated with this disease. Several studies have reported changes in the metabolism of arachidonic acid and the profile of fatty acids, ceramides, phospholipids and lipid peroxidation products. Nevertheless, the understanding of the modulation of circulating lipids at the molecular level in multiple sclerosis remains unclear. In the present study,...
3 CitationsSource
#1Helena Ferreira (University of Aveiro)H-Index: 10
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. Maria do Rosário Domingues (University of Aveiro)H-Index: 4
view all 4 authors...
Rheumatoid arthritis (RA) is a highly debilitating chronic inflammatory autoimmune disease most prevalent in women. The true etiology of this disease is complex, multifactorial, and is yet to be completely elucidated. However, oxidative stress and lipid peroxidation are associated with the development and pathogenesis of RA. In this case, oxidative damage biomarkers have been found to be significantly higher in RA patients, associated with the oxidation of biomolecules and the stimulation of inf...
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#1Susana S. AveiroH-Index: 1
#2Tânia Melo (University of Aveiro)H-Index: 15
Last. Ana S. P. MoreiraH-Index: 20
view all 10 authors...
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