Mark S. Pearce
Newcastle University
EpidemiologyCancerInternal medicinePublic healthSurgerySocioeconomic statusDemographyPsychologyPediatricsProspective cohort studyCohort studyYoung adultBody mass indexPopulationIncidence (epidemiology)Risk factorObesityBirth weightMedicineCohortGerontology
377Publications
61H-index
11.5kCitations
Publications 366
Newest
#1Tania L. Jones (RVI: Royal Victoria Infirmary)
#2Mohammed S. Esa (RVI: Royal Victoria Infirmary)
Last. Fraser Birrell (RVI: Royal Victoria Infirmary)H-Index: 30
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Abstract null null Circulating microRNAs (c-miRs) show promise as biomarkers. This systematic review explores their potential association with age-related fracture/osteoporosis (OP), osteoarthritis (OA) and sarcopenia (SP), as well as cross-disease association. Most overlap occurred between OA and OP, suggesting potentially shared microRNA activity. There was little agreement in results across studies. Few reported receiver operating characteristic analysis (ROC) and many identified significant ...
1 CitationsSource
#1Charlotte C Currie (Newcastle University)H-Index: 6
#2SJ Stone (Newcastle University)H-Index: 5
Last. Mark S. Pearce (Newcastle University)H-Index: 61
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One-third of the UK population is composed of problem-oriented dental attenders, seeking dental care only when they have acute dental pain or problems. Patients seek urgent dental care from a range...
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The combined role of objectively assessed moderate-vigorous intensity physical activity (MVPA) and sedentary behaviour (SB) is unclear in obesity prevention. This study aimed to identify latent groups for MVPA and SB trajectories from childhood to adolescence and examine their relationship with obesity risk at adolescence. From the Gateshead Millennium Study, accelerometer-based trajectories of time spent in MVPA and SB at ages 7, 9, 12, and 15 were derived as assigned as the predictor variable....
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#1H. D. Jeffry Hogg (Newcastle University)H-Index: 2
#2Nicholas D H Chung (Newcastle University)H-Index: 1
Last. Sandro Di Simplicio (Newcastle upon Tyne Hospitals NHS Foundation Trust)H-Index: 2
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BACKGROUND Thousands of phacoemulsification surgeries are performed on eyes with age-related macular degeneration (AMD) complicated by choroidal neovascular membrane (CNV) in the United Kingdom each year. As populations age this number is expected to rise. Controversy over phacoemulsification's influence on CNV activity limits the information which clinicians and these patients use to decide on surgery. This observational study aims to resolve this controversy by reporting on intravitreal inject...
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#1Jordan Reed (Newcastle University)
#2Nicholas D H Chung (Newcastle University)H-Index: 1
Last. Sandro Di Simplicio (RVI: Royal Victoria Infirmary)
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#1Viviana Albani (Newcastle University)H-Index: 5
#2Luke Vale (Newcastle University)H-Index: 70
Last. Liudmila LiutskoH-Index: 6
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Abstract Health surveillance initiatives targeted at populations evacuated from, and residing in, areas affected by radiation contamination were implemented by international institutions as well as national and local governments after the nuclear accidents of Chernobyl and Fukushima Dai-ichi nuclear power plants. Most of these initiatives included a component of childhood thyroid cancer monitoring, with the more comprehensive schemes corresponding to national programmes of health monitoring for ...
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#1Nicholas D. Embleton (Newcastle University)H-Index: 53
#2Claire L Wood (Newcastle University)H-Index: 12
Last. Victoria GrahameH-Index: 7
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BACKGROUND Achieving adequate nutrition in preterm infants is challenging. The post-discharge period may be critical for influencing growth and cognitive outcomes. We studied the effects of post-discharge nutrition on childhood cognition. METHODS Preterm-born children were randomized at ~36 weeks corrected age (CGA) to either preterm formula (PTF) or term formula (TF) until 6 months, or PTF until 40 weeks CGA, then TF until 6 months (crossover group). Childhood cognition was assessed using the s...
1 CitationsSource
#1Joyce Chzi Ching Chee (Newcastle University)
#2Sylvia Wei Wei Kong (Newcastle University)
Last. Edmund Ong (Newcastle University)H-Index: 13
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# Background Adherence to preventative measures designed to mitigate transmission of COVID-19 depends on individual’s understanding and perception of COVID-19. The objective of this study was to assess the knowledge, perceptions, behavioural adaptation and psychological well-being related to COVID-19 among students attending Newcastle University Medicine Malaysia. # Methods A cross-sectional study was conducted using convenience sampling of students. The self-administered online questionnaire wa...
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#1Natassia Robinson (Newcastle University)H-Index: 2
#2Heather Brown (Newcastle University)H-Index: 13
Last. Jill A. McKay (Northumbria University)H-Index: 15
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BACKGROUND High early postnatal weight gain has been associated with childhood adiposity; however, the mechanism remains unknown. DNA methylation is a hypothesised mechanism linking early life exposures and subsequent disease. However, epigenetic changes associated with high early weight gain have not previously been investigated. Our aim was to investigate the associations between early weight gain, peripheral blood DNA methylation, and subsequent overweight/obese. Data from the UK Avon Longitu...
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#1H. D. Jeffry Hogg (Newcastle University)H-Index: 2
#2S. James Talks (Newcastle upon Tyne Hospitals NHS Foundation Trust)H-Index: 1
Last. Sandro Di Simplicio (Newcastle upon Tyne Hospitals NHS Foundation Trust)H-Index: 2
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PURPOSE Central retinal vein occlusion (CRVO) can be complicated by macular oedema, requiring intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF). CRVO can cause neovascularisation, potentially causing persistent pain if not identified early. Whilst clinical trial data describe visual and anti-neovascular benefit from anti-VEGF there are limited real-world data. METHODS A retrospective cohort study of a consecutive series of patients found from a review of the electron...
1 CitationsSource