Sonu Gandhi
Amity Institute of Biotechnology
AnalyteColloidal goldConjugated systemSurface modificationDetection limitBiophysicsAptamerFabricationNanomaterialsField-effect transistorMolecular biologyNanoparticleVirologyBiosensorVitronectinNeuroscienceNanotechnologyElectrodeBlightChemistryMaterials scienceEpitopeVirusAlternaria solaniIron oxide nanoparticlesUrineDipstickImmunoassayTin oxideGrapheneAflatoxinNanosensorChromatographyBiomoleculeCarbon nanotubeBiochemistryUrokinase receptorMedicineMicrofluidicsBiology
58Publications
19H-index
947Citations
Publications 55
Newest
#1Raghuraj S. ChouhanH-Index: 10
#2Milena HorvatH-Index: 3
Last. Sonu GandhiH-Index: 19
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Magnetic nanoparticles gained considerable attention in last few years due to their remarkable properties. Superparamaganetism, non-toxicity, biocompatibility, chemical inertness, and environmental friendliness are some of the properties that make iron oxide nanoparticles (IONPs) an ideal choice for biomedical applications. Along with being easily tuneable and a tailored surface for conjugation of IONPs, their physio-chemical and biological properties can also be varied by modifying the basic pa...
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#1Deepshikha ShahdeoH-Index: 4
#2Veerbhan KesarwaniH-Index: 1
Last. Sonu GandhiH-Index: 19
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Abstract Targeting cell surface receptors for specific drug delivery in cancer has garnered lot of attention. Urokinase plasminogen activator receptor (uPAR), a surface biomarker, is overexpressed on many tumours including breast, colorectal, prostate, and ovarian cancers. Binding of growth factor domain (GFD) of urokinase plasminogen activator (uPA) with uPAR lead to its close conformation, and allow somatomedin B domain (SMB) of vitronectin binding by allosteric modulation. In-silico docking o...
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#1Raghuraj S. ChouhanH-Index: 10
#2Ivan JermanH-Index: 22
Last. Milena HorvatH-Index: 64
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1 CitationsSource
#1Sonu Gandhi (Amity Institute of Biotechnology)H-Index: 19
#2Saad M. Alshehri (KSU: King Saud University)H-Index: 37
Antibodies play a vital role in a variety of applications from diagnostics, imaging, and therapeutics. The stability of antibodies is one of the most important key attributes for its prolonged activity and functionality. Here, we demonstrate a detailed comparative study of the molecular stability of the rabbit immunoglobulin G (IgG) and chicken egg yolk immunoglobulin Y (IgY) at different pH, temperatures, and time points. The molecular stability of IgG and IgY is compared on the basis of its bi...
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#2Subhasis MahariH-Index: 3
Last. Sonu GandhiH-Index: 19
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#1Akanksha RobertsH-Index: 3
#2Deepshikha ShahdeoH-Index: 4
Last. Sonu GandhiH-Index: 19
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Immobilization techniques involve the confining/anchoring of a molecule (enzyme or cells) in or on an inert support/substrate matrix for stability, increased efficiency and easy recoverability of the molecule. The immobilization of molecules to a substrate is carried out on the basis of five major principle methods, i.e. adsorption, entrapment, membrane confinement (encapsulation), cross-linking (copolymerization) and covalent binding. Various different scientific processes make use of immobiliz...
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#1Emir Yasun (UCSB: University of California, Santa Barbara)H-Index: 8
#2Sonu GandhiH-Index: 19
Last. Hamed Arami (Stanford University)H-Index: 30
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Abstract Hollow particles have been extensively used in bioanalytical and biomedical applications for almost two decades due to their unique and tunable optoelectronic properties as well as their significantly high loading capacities. These intrinsic properties led them to be used in various bioimaging applications as contrast agents, controlled delivery (i.e. drugs, nucleic acids and other biomolecules) platforms and photon-triggered therapies (e.g. photothermal and photodynamic therapies). Sin...
1 CitationsSource
#2Veerbhan Kesarwani (Allahabad University)H-Index: 1
Last. Shailesh SharmaH-Index: 2
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Genomics-led researches are engaged in tracing virus expression pattern, and induced immune responses in human to develop effective vaccine against COVID-19. In this study, targeted expression profiling and differential gene expression analysis of major histocompatibility complexes and innate immune system genes were performed through SARS-CoV-2 infected RNA-seq data of human cell line, and virus transcriptome was generated for T-and B-cell epitope prediction. Docking studies of epitopes with MH...
1 CitationsSource
#1Akanksha RobertsH-Index: 3
#2Neha Chauhan (IISc: Indian Institute of Science)H-Index: 7
Last. Sonu GandhiH-Index: 19
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Graphene, a two-dimensional nanomaterial, has gained immense interest in biosensing applications due to its large surface-to-volume ratio, and excellent electrical properties. Herein, a compact and user-friendly graphene field effect transistor (GraFET) based ultrasensitive biosensor has been developed for detecting Japanese Encephalitis Virus (JEV) and Avian Influenza Virus (AIV). The novel sensing platform comprised of carboxy functionalized graphene on Si/SiO2 substrate for covalent immobiliz...
3 CitationsSource
#1Shruti Shukla (National Institute of Food Technology Entrepreneurship and Management)H-Index: 5
#2Yuvaraj Haldorai (Bharathiar University)H-Index: 25
Last. Young-Kyu Han (Dongguk University)H-Index: 49
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Abstract In this research, we successfully synthesized a reduced graphene oxide/tin oxide (rGO/SnO2) composite for the electrochemical detection of fungal contaminant, patulin (PAT) that does not require a biological or chemical receptor or specific antibodies. The resulting rGO/SnO2 composite exhibited promising electrochemical properties and demonstrated outstanding performance in the direct measurement of PAT levels in contaminated apple juice samples. The differential pulse voltammetric resp...
6 CitationsSource