Carola Severi
Sapienza University of Rome
Internal medicineEndocrinologySurgeryPathologyContraction (grammar)ReceptorChemistryImmunologyMyocyteOxidative stressHelicobacter pyloriLactobacillus rhamnosusIrritable bowel syndromeBombesinGastritisLipopolysaccharideSmooth muscleMedicineBiologyMicrobiologyGastroenterologyCell biology
Publications 163
#2G. BrunoH-Index: 11
Last. Carola SeveriH-Index: 25
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#1Francesca Aprile (Sapienza University of Rome)H-Index: 3
#2G. Bruno (Sapienza University of Rome)H-Index: 11
Last. Stefano Pontone (Sapienza University of Rome)H-Index: 13
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Gut microbiota plays an important role in human health. It may promote carcinogenesis and is related to several diseases of the gastrointestinal tract. This study of microbial dysbiosis in the etiology of colorectal adenoma aimed to investigate the possible causative role of microbiota in the adenoma-carcinoma sequence and its possible preventive role. A systematic, PRISMA-guided review was performed. The PubMed database was searched using "adenoma microbiota" and selecting original articles bet...
The Mediterranean diet is worldwide recognized as a good prototype of nutrition due to the conspicuous intake of olive oil, nuts, red wine, legumes, fruit, and vegetables, all fundamental elements rich in antioxidant substances and polyphenols. Polyphenols are a wide range of phytochemicals and/or synthetic chemical compounds with proven beneficial properties for human health. In the present review, we critically summarize the well-characterized antioxidant and anti-inflammatory properties of po...
#2Emanuela RibichiniH-Index: 3
Last. Danilo BadialiH-Index: 14
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#1Marilia CarabottiH-Index: 14
#2Antonio Maria Morselli Labate (UNIBO: University of Bologna)H-Index: 25
Last. Bruno AnnibaleH-Index: 67
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Abstract Background Pathogenesis of acute diverticulitis and diverticular bleeding remains poorly defined, and few data compare directly risk factors for these complications. Aims to assess differences in clinical features, lifestyles factors and concurrent drug use in patients with acute diverticulitis and those with diverticular bleeding. Methods Data were obtained from the REMAD Registry, an ongoing 5-year prospective, observational, multicenter, cohort study conducted on 1,217 patients. Pati...
#1Piera ZaccariH-Index: 3
#2Emanuela RibichiniH-Index: 3
Last. Carola SeveriH-Index: 25
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#1Rosa Vona (ISS: Istituto Superiore di Sanità)H-Index: 15
#2L. Pallotta (Sapienza University of Rome)H-Index: 6
Last. Paola Matarrese (ISS: Istituto Superiore di Sanità)H-Index: 60
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Accumulating evidence shows that oxidative stress plays an essential role in the pathogenesis and progression of many diseases. The imbalance between the production of reactive oxygen species (ROS) and the antioxidant systems has been extensively studied in pulmonary, neurodegenerative cardiovascular disorders; however, its contribution is still debated in gastrointestinal disorders. Evidence suggests that oxidative stress affects gastrointestinal motility in obesity, and post-infectious disorde...
#1Giulia Scalese (Sapienza University of Rome)H-Index: 1
#2Carola Severi (Sapienza University of Rome)H-Index: 25
Abstract null null The gut–brain axis encompasses bidirectional communications between the enteric nervous system and the central nervous system that contribute to a proper coordination of gut functions in normal conditions and in response to psychological and physical stressors. The parallel involvement of multiple interacting brain and gut networks has led to the concept of considering the system composed not as single entities but as “brain connectome” and “gut connectome.” The homeostasis of...
#1Federica Avorio (ISMETT)H-Index: 5
#2Emanuele Cerulli Irelli (Sapienza University of Rome)H-Index: 5
Last. Mario Manfredi (Sapienza University of Rome)H-Index: 32
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Introduction: The complex relationship between the microbiota-gut-brain axis (MGBA) and epilepsy has been increasingly investigated in preclinical studies. Conversely, evidence from clinical studies is still scarce. In recent years, the pivotal role of MGBA dysregulation in the pathophysiology of functional gastrointestinal disorders (FGID) has been recognized. With this background, we aimed to investigate the prevalence of FGID in patients with epilepsy (PWE) and the possible impact of bowel mo...
#1Serena Stigliano (Sapienza University of Rome)H-Index: 11
#2Piera Zaccari (Sapienza University of Rome)H-Index: 3
Last. Carola Severi (Sapienza University of Rome)H-Index: 25
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