Tadashi Yoshino
Okayama University
Internal medicinePathologyOncologyAntigenMolecular biologyAntibodyLymphatic systemChemistryImmunologyImmunohistochemistryBiopsyFollicular lymphomaB cellDiffuse large B-cell lymphomaLymphomaMALT lymphomaCancer researchMedicineBiologyGastroenterology
744Publications
77H-index
20.4kCitations
Publications 737
Newest
#1Sawako OnoH-Index: 1
#2Hidenori MarunakaH-Index: 6
Last. Tadashi YoshinoH-Index: 77
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Lymphoepithelial carcinoma (LEC) of the tongue is a rare subtype of squamous cell carcinoma. Histologically, it is an undifferentiated carcinoma with rich lymphocyte and plasma cell infiltration. The most common location for LEC in the head and neck is the salivary glands, and LEC of the oral cavity is extremely rare. The second case report of LEC in the lateral tongue is presented. In addition, a review of the literature was performed, and the relationship between LEC and Epstein–Barr virus inf...
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#2Takehiro TanakaH-Index: 22
Last. Tadashi YoshinoH-Index: 77
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#1Tomoka Ikeda (Okayama University)H-Index: 2
#2Yuka Gion (RMIT: RMIT University)H-Index: 13
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
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Abstract null null Sarcoidosis-lymphoma syndrome associated with portal hypertension is very rare. A 68-year-old female presented with a 5 kg weight loss in 6 months. Soluble interleukin-2 receptor activity was increased and total platelet count was decreased. Contrast-enhanced computed tomography showed the presence of hepatosplenomegaly and a 3 cm-sized tumor in segment 3 of the liver. The hepatic venous catheterization showed mild portal hypertension. On fluorodeoxyglucose-positron emission t...
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#1Akira Satou (Aichi Medical University)H-Index: 8
#2Tetsuya Tabata (Okayama University)H-Index: 3
Last. Shigeo Nakamura (Nagoya University)H-Index: 101
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Plasma cell differentiation (PCD) is frequently observed in some entities of non-Hodgkin B cell lymphoma, including both low-grade and high-grade lymphomas. However, except for plasmablastic lymphoma and primary effusion lymphoma, EBV+ B cell lymphoproliferative disorder (LPD) with PCD has not been well addressed due to its rarity. We clinicopathologically examined five cases of nodal EBV+ polymorphic B cell LPD with PCD (PBLPD-PCD) initially diagnosed as polymorphic EBV+ diffuse large B cell ly...
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#1Hiroki Kobayashi (Okayama University)H-Index: 1
#2Noboru Asada (Okayama University)H-Index: 15
Last. Yoshinobu Maeda (Okayama University)H-Index: 29
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Waldenstrom macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a rare indolent B-cell neoplasm, and a gain-of-function mutation in the myeloid differentiation primary response 88 (MYD88), L265P, is a commonly recurring mutation in patients with WM/LPL. Histological transformation of WM/LPL to an aggressive lymphoma such as diffuse large B-cell lymphoma (DLBCL) is rare, and transformed DLBCL has a worse prognosis than de novo DLBCL, partly because transformed DLBCL is mostly classified as...
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#1Atsuko Nasu (RMIT: RMIT University)
#1Atsuko Nasu (RMIT: RMIT University)H-Index: 2
Last. Yasuharu Sato (RMIT: RMIT University)H-Index: 32
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Differentiation between adult T-cell leukemia/lymphoma (ATLL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), is often challenging based on pathological findings alone. Although serum anti-HTLV-1 antibody positivity is required for ATLL diagnosis, this information is often not available at the time of pathological diagnosis. Therefore, we examined whether the expression of SOX4 and p16 would be helpful for differentiating the two disease entities. We immunohistochemically exa...
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#1Kohei Taniguchi (Okayama University)H-Index: 4
#2Hiroyuki Yanai (Okayama University)H-Index: 19
Last. Tadashi Yoshino (Okayama University)H-Index: 77
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Secretory carcinoma of the skin is an extremely rare adnexal tumor, histopathologically identical to homologous lesions in the salivary glands and breast tissue. Although this tumor was previously reported as indolent, we report a case of secretory carcinoma of the skin with metastases and recurrence. The patient, 31-year-old women, had a subcutaneous mass in the right axilla. The resected specimen contained a circumscribed mass, with proliferating tumor cells that exhibited prominent nucleoli. ...
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Immunoglobulin G4-related disease (IgG4-RD) is a systemic disorder characterized by tissue fibrosis and intense lymphoplasmacytic infiltration, causing progressive organ dysfunction. Activation-induced cytidine deaminase (AID), a deaminase normally expressed in activated B-cells in germinal centers, edits ribonucleotides to induce somatic hypermutation and class switching of immunoglobulin. While AID expression is strictly controlled under physiological conditions, chronic inflammation has been ...
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#1Wataru Kitamura (Okayama University)
#2Daisuke Ennishi (Okayama University)H-Index: 16
Last. Yoshinobu Maeda (Okayama University)H-Index: 29
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A 72-year-old man presented with chorea while undergoing treatment for recurrence of nodal peripheral T-cell lymphoma with T follicular helper (TFH) phenotype. An examination by brain N-isopropyl-p-iodoamphetamine (123I-IMP)-single photon emission computed tomography (SPECT) revealed no abnormalities other than a decreased cerebral blood flow (CBF) in the left striatum. After four courses of salvage chemotherapy, his clinical symptoms and asymmetric cerebral perfusion improved, suggesting that t...
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