Andrea Gallina
Vita-Salute San Raffaele University
DissectionInternal medicineRadiologyUrologySurgeryOncologyStage (cooking)CystectomyBiopsyProstateProstatectomyErectile dysfunctionPembrolizumabProstate cancerBladder cancerLymph nodeIn patientNomogramProportional hazards modelGeneral surgeryMedicine
Publications 692
#1Andrea NecchiH-Index: 35
#2Laura MarandinoH-Index: 10
Last. Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 138
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The similar clinical behavior, overlapping therapeutic patterns, and several clinical trials addressing the neoadjuvant and first-line therapy settings for bladder cancer support the call for a more uniform definition of "locally advanced" disease. We highlight the diverse therapeutic opportunities that patients with locally advanced bladder cancer may receive at present. Multimodal management, and post-therapy surgery in particular, may still have a role in selected patients.
1 CitationsSource
#1Filippo Pederzoli (UniSR: Vita-Salute San Raffaele University)H-Index: 13
#2Marco Bandini (UniSR: Vita-Salute San Raffaele University)H-Index: 24
Last. Andrea Necchi (UniSR: Vita-Salute San Raffaele University)H-Index: 13
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In locally advanced and metastatic malignancies, antibiotic (ATB) therapy has a negative effect on immunotherapy efficacy. Therefore, we aimed to evaluate whether ATB therapy and use of specific ATB classes with concomitant neoadjuvant pembrolizumab affected pathologic complete response (ypT0N0) and relapse-free survival (RFS) for patients with clinical T2-4N0M0 bladder cancer enrolled in the PURE-01 study. Of the 149 patients evaluated, 48 (32%) received any concomitant ATB therapy. The ATB cla...
#1Alberto MartiniH-Index: 27
#2Luca AfferiH-Index: 2
Last. Marco MoschiniH-Index: 27
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PURPOSE Presently, major guidelines do not provide specific recommendations on oncologic surveillance for patients who harbor VH BCa at radical cystectomy. We aimed to create a personalized follow-up scheme that dynamically weighs OCM versus the risk of recurrence for VH BCa, and to compare it with a similar one for pUC. METHODS Within a multi-institutional registry, 528 and 1,894 patients with VH BCa and pUC, were identified. The Weibull regression was used to detect the time points after which...
#1Praful Ravi (Harvard University)H-Index: 21
#2Gregory R. Pond (McMaster University)H-Index: 72
Last. Guru Sonpavde (Harvard University)H-Index: 60
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OBJECTIVES To evaluate outcomes of patients achieving
#1Angelo PorrecaH-Index: 13
#2Gian Maria BusettoH-Index: 19
Last. Daniele D'AgostinoH-Index: 13
view all 41 authors...
#1Giuseppe RosielloH-Index: 9
#2Giorgio Gandaglia (UniSR: Vita-Salute San Raffaele University)H-Index: 47
Last. Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 138
view all 17 authors...
Abstract Background Prospective data collection for perioperative outcomes might increase awareness of surgical results obtained for patients with prostate cancer (PCa) undergoing robot-assisted radical prostatectomy (RARP). This would prompt the implementation of measures aimed at reducing the risk of adverse outcomes. Objective To assess the efficacy of an audit and feedback process aimed at identifying the most common complications after RARP and at implementing measures to improve outcomes. ...
#1Umberto Capitanio (UniSR: Vita-Salute San Raffaele University)H-Index: 62
#2Riccardo AutorinoH-Index: 68
Last. Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 138
view all 15 authors...
1 CitationsSource
Abstract Background Data regarding the role of positron emission tomography/computed tomography (PET/CT) to stage lymph nodes in patients receiving neoadjuvant immunotherapy before radical cystectomy are lacking. The aim of this study is to evaluate the role of PET/CT to predict the pathologic lymph node involvement (LNI) in patients with MIBC receiving neoadjuvant pembrolizumab within the PURE-01 trial (NCT02736266). Material and methods Three courses of pembrolizumab were administered before r...
1 CitationsSource
#1Giuseppe Rosiello (UdeM: Université de Montréal)H-Index: 9
#2Carlotta Palumbo (UdeM: Université de Montréal)H-Index: 6
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 116
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Abstract Background The increased awareness regarding the sex gap in bladder cancer (BCa) care over the last decade may have resulted in more timely-wise referral patterns and treatment of female patients with BCa. Thus, we tested the association of sex with disease stage at presentation, as well as with cancer-specific mortality (CSM) after radical cystectomy (RC) in a contemporary cohort of patients with nonmetastatic urothelial bladder cancer (UCUB). Methods Within the Surveillance, Epidemiol...
3 CitationsSource