David Atkinson
University College London
AlgorithmOpticsPhysicsInternal medicineRadiologyBiomedical engineeringWorld Wide WebIterative reconstructionMagnetic resonance imagingDiffusion MRIArtificial intelligencePattern recognitionEcologyInformation retrievalData scienceProstate cancerPopulationNuclear medicineComputer visionMathematicsComputer scienceNuclear magnetic resonanceMedicineBiology
Publications 573
#1Marianthi-Vasiliki Papoutsaki (UCL: University College London)H-Index: 2
#2Harbir S. Sidhu (UCL: University College London)H-Index: 14
Last. Dawn Carnell (UCLH: University College Hospital)H-Index: 1
view all 12 authors...
Diffusion MRI characteristics assessed by apparent diffusion coefficient (ADC) histogram analysis in head and neck squamous cell carcinoma (HNSCC) have been reported as helpful in classifying tumours based on diffusion characteristics. There is little reported on HNSCC lymph nodes classification by diffusion characteristics. The aim of this study was to determine whether pretreatment nodal microstructural diffusion MRI characteristics can classify diseased nodes of patients with HNSCC from norma...
#1Marco Palombo (UCL: University College London)H-Index: 16
#2Valindria (UCL: University College London)
Last. Daniel C. Alexander (UCL: University College London)H-Index: 72
view all 11 authors...
Objectives. The Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumours (VERDICT) is a non-invasive MRI technique that has shown promising results in clinical settings discriminating normal from malignant tissue and Gleason grade 3+3 from 3+4. However, VERDICT currently does not account for the inherent relaxation properties of the tissue, whose quantification could provide additional information and enhance its diagnostic power. The aim of this work is to introduce relaxation...
#1Tom SyerH-Index: 1
Last. Shonit PunwaniH-Index: 42
view all 7 authors...
Computer-aided diagnosis (CAD) of prostate cancer on multiparametric magnetic resonance imaging (mpMRI), using artificial intelligence (AI), may reduce missed cancers and unnecessary biopsies, increase inter-observer agreement between radiologists, and alleviate pressures caused by rising case incidence and a shortage of specialist radiologists to read prostate mpMRI. However, well-designed evaluation studies are required to prove efficacy above current clinical practice. A systematic search of ...
#1Hanrong Tan (QMUL: Queen Mary University of London)H-Index: 1
#2Andrew G. Hirst (NTU: Nottingham Trent University)H-Index: 34
Last. Pavel Kratina (QMUL: Queen Mary University of London)H-Index: 19
view all 4 authors...
1 CitationsSource
#1Manil D Chouhan (UCL: University College London)H-Index: 8
#2H Fitzke (QMUL: Queen Mary University of London)H-Index: 5
Last. Stuart A. Taylor (UCL: University College London)H-Index: 60
view all 10 authors...
MR elastography and magnetization-tagging use liver stiffness (LS) measurements to diagnose fibrosis but require physical drivers, specialist sequences and post-processing. Here we evaluate non-rigid registration of dynamic two-dimensional cine MRI images to measure cardiac-induced liver deformation (LD) as a measure of LS by (i) assessing preclinical proof-of-concept, (ii) clinical reproducibility and inter-reader variability, (iii) the effects of hepatic hemodynamic changes and (iv) feasibilit...
#1Woon Js (University of Liverpool)
#2David Atkinson (University of Liverpool)H-Index: 68
Last. Parr Cl (University of Liverpool)
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The most diverse and abundant family of termites, the Termitidae, evolved in warm, wet African tropical forests. Since then, they have colonised grassy biomes such as savannas. These environments have more extreme temperatures than tropical forests, and greater temporal fluctuations (both annually and diurnally) that are challenging for soft-bodied ectotherms. We propose that that a likely mechanism that facilitated the expansion from forest to savanna was the widening of physiological limits of...
#1Marianthi-Vasiliki Papoutsaki (UCL: University College London)H-Index: 2
#2Clare Allen (UCLH: University College Hospital)H-Index: 35
Last. Shonit Punwani (UCL: University College London)H-Index: 42
view all 9 authors...
OBJECTIVES National guidelines recommend prostate multiparametric (mp) MRI in men with suspected prostate cancer before biopsy. In this study, we explore prostate mpMRI protocols across 14 London hospitals and determine whether standardisation improves diagnostic quality. METHODS An MRI physicist facilitated mpMRI set-up across several regional hospitals, working together with experienced uroradiologists who judged diagnostic quality. Radiologists from the 14 hospitals participated in the assess...
#1Hayley PyeH-Index: 9
#2Saurabh SinghH-Index: 5
Last. Hayley C. WhitakerH-Index: 7
view all 37 authors...
Objectives: To assess the clinical outcomes of mpMRI before biopsy and evaluate the space remaining for novel biomarkers. Methods: The INNOVATE study was set up to evaluate the validity of novel fluidic biomarkers in men with suspected prostate cancer who undergo pre-biopsy mpMRI. We report the characteristics of this clinical cohort, the distribution of clinical serum biomarkers, PSA and PSA density (PSAD), and compare the mpMRI Likert scoring system to the Prostate Imaging–Reporting and Data S...
#1Kerstin Klaser ('KCL': King's College London)H-Index: 6
#1Kerstin Kläser (UCL: University College London)H-Index: 3
Last. Sebastien Ourselin ('KCL': King's College London)H-Index: 91
view all 10 authors...
Abstract The assessment of the quality of synthesised/pseudo Computed Tomography (pCT) images is commonly measured by an intensity-wise similarity between the ground truth CT and the pCT. However, when using the pCT as an attenuation map ( μ -map) for PET reconstruction in Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI) minimising the error between pCT and CT neglects the main objective of predicting a pCT that when used as μ -map reconstructs a pseudo PET (pPET) which is as si...
1 CitationsSource