Youqing Shen
Qingdao University
Radical polymerizationMicelleBiophysicsGene deliveryAtom-transfer radical-polymerizationNanoparticleCopolymerNanotechnologyChemistryPolymer chemistryMaterials scienceIn vivoDrug deliveryChemical engineeringPolymerizationCancer researchPolymerTransfectionDendrimerCancer cell
465Publications
63H-index
13.8kCitations
Publications 409
Newest
#1Ruixia Yang (Qingdao University)H-Index: 5
#2Qiaohong Peng (Qingdao University)H-Index: 11
Last. Hailin Cong (Qingdao University)H-Index: 20
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Abstract Yolk-shell Fe3O4@MOF-5 nanocomposites were synthesized by utilizing a simple solvothermal method. The physicochemical properties of the yolk-shell Fe3O4@MOF-5 nanocomposites were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Brunauer–Emmett–Teller (BET) and vibrating sample magnetometer (VSM) methods. The nanocomposites had a catalytic yolk, a hollow cavity and a p...
1 CitationsSource
#1Adeel Ahmed (Qingdao University)H-Index: 5
#2Muhammad Usman (Qingdao University)H-Index: 7
Last. Hailin Cong (Qingdao University)H-Index: 20
view all 6 authors...
Abstract The increasing worldwide pollution of water resources with dyes has emphasized the need to develop highly versatile and effective approaches for their remediation. In this study, zirconium substituted manganese cobalt ferrite (Mn0.2Co0.8ZrxFe2−xO4) nanoparticles, and their composites with reduced graphene oxide (Mn0.2Co0.8ZrxFe2−xO4/rGO) were synthesized and used as effective photocatalyst materials for the degradation of dyes. X-ray diffraction analysis was executed to probe the cubic ...
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#1He Ma (Qingdao University)
#2Song Wang (Qingdao University)H-Index: 4
Last. Hailin Cong (Qingdao University)H-Index: 20
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Bio-nanochannels in living organisms participate in the physiological activities by selectively transporting ions through cell membranes. The structure and function of biological ion channels inspire the development of artificial ion nanochannels with practical applications. The bioinspired nanochannels based on polymer materials present good mechanical stability, high-performance ion transport and designability, which have attracted much attention. In this review, we mainly focus on the fabrica...
1 CitationsSource
#1Zhen Zhang (ZJU: Zhejiang University)H-Index: 4
#2Nasha Qiu (ZJU: Zhejiang University)H-Index: 7
Last. Youqing Shen (ZJU: Zhejiang University)H-Index: 63
view all 9 authors...
Cationic polymers dynamically complex DNA into complexes (polyplexes). So, upon dilution, polyplexes easily dissociate and lose transfection ability, limiting their in vivo systemic gene delivery. Herein, it is found that polyplex's stability and endocytosis pathway determine its transfection dose-dependence. The polyplexes of hydrophilic polycations have dose-dependent integrity and lysosome-trafficking endocytosis; at low doses, most of these polyplexes dissociate, and the remaining few are in...
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#1Shuaibing Guo (Qingdao University)
#2Bing Yu (Qingdao University)H-Index: 19
Last. Hailin Cong (Qingdao University)H-Index: 20
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Abstract The three-dimensional colloidal crystal materials have unique optical properties and spatial structure due to their ordered arrangement and have great potential to prepare three-dimensionally ordered microporous (3DOM) materials. This review outlines various methods for preparing three-dimensional colloidal crystals (3DCCs). The preparation methods of commonly used colloidal particles are introduced in detail, and the effects of different parameters on the assembly of 3DCCs are discusse...
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#1Jing Liu (ZJU: Zhejiang University)H-Index: 1
#2Zhihao Zhao (ZJU: Zhejiang University)H-Index: 1
Last. Youqing Shen (ZJU: Zhejiang University)H-Index: 63
view all 10 authors...
Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune checkpoint, which reverses T cell dysfunction/exhaustion and shows success in treating cancer. Here, we report a histone demethylase inhibitor, 5-carboxy-8-hydroxyquinoline (IOX1), which inhibits tumour histone demethylase Jumonji domain-containing 1A (JMJD1A) and thus downregulates its downstream β-catenin and subsequent PD-L1, providing an ant...
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#1Muhammad Usman (Qingdao University)H-Index: 7
#2Adeel Ahmed (Qingdao University)H-Index: 5
Last. Hailin Cong (Qingdao University)H-Index: 20
view all 6 authors...
Abstract Heavy metals and endocrine disrupters often co-exist in wastewater, while their possible competition behaviours make uptake removal more challenging. Therefore, β-Cyclodextrin based nanocomposite adsorbent was successfully fabricated (β-Cyclodextrin/ZrO2) for the simultaneous uptake of Pb(II) and Bisphenol A from wastewater. FTIR, XRD, and XPS confirmed the successful fabrication of the β-Cyclodextrin/ZrO2 nanocomposite. In this setting, oxygen-containing groups are primarily responsibl...
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#1Siqin Chen (ZJU: Zhejiang University)H-Index: 1
#2Yin Zhong (ZJU: Zhejiang University)H-Index: 3
Last. Youqing Shen (ZJU: Zhejiang University)H-Index: 63
view all 23 authors...
Effective anticancer nanomedicines need to exhibit prolonged circulation in blood, to extravasate and accumulate in tumours, and to be taken up by tumour cells. These contrasting criteria for persistent circulation and cell-membrane affinity have often led to complex nanoparticle designs with hampered clinical translatability. Here, we show that conjugates of small-molecule anticancer drugs with the polyzwitterion poly(2-(N-oxide-N,N-diethylamino)ethyl methacrylate) have long blood-circulation h...
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#2Bing YuH-Index: 19
Last. Youqing ShenH-Index: 63
view all 5 authors...
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#1Shengjun Xu (ZJU: Zhejiang University)H-Index: 1
#1Shengjun Xu (ZJU: Zhejiang University)H-Index: 3
Last. Xiao Xu (ZJU: Zhejiang University)H-Index: 29
view all 17 authors...
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