Nathan S. White
University of California, San Diego
Fluid-attenuated inversion recoveryPhysicsRadiologyPathologyMagnetic resonance imagingHyperintensityDiffusion MRIArtificial intelligencePsychologyNeuroscienceProstateGliomaProstate cancerCerebral cortexWhite matterNuclear medicineSpectrum imagingNuclear magnetic resonanceVoxelNeuroimagingMedicineFractional anisotropy
83Publications
28H-index
2,649Citations
Publications 83
Newest
#1Igor Vidic (NTNU: Norwegian University of Science and Technology)H-Index: 6
#2Liv Egnell (NTNU: Norwegian University of Science and Technology)H-Index: 3
Last. Pål Erik Goa (NTNU: Norwegian University of Science and Technology)H-Index: 17
view all 9 authors...
PURPOSE: To evaluate different non-Gaussian representations for the diffusion-weighted imaging (DWI) signal in the b-value range 200 to 3000 s/mm(2) in benign and malignant breast lesions. METHODS: Forty-three patients diagnosed with benign (n = 18) or malignant (n = 25) tumors of the breast underwent DWI (b-values 200, 600, 1200, 1800, 2400, and 3000 s/mm(2) ). Six different representations were fit to the average signal from regions of interest (ROIs) at different b-value ranges. Quality of fi...
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#1Emilie T. Reas (UCSD: University of California, San Diego)H-Index: 13
#2Donald J. Hagler (UCSD: University of California, San Diego)H-Index: 90
Last. James B. Brewer (UCSD: University of California, San Diego)H-Index: 54
view all 10 authors...
BACKGROUND: Although amyloid-beta (Abeta) and microstructural brain changes are both effective biomarkers of Alzheimer's disease, their independent or synergistic effects on cognitive decline are unclear. OBJECTIVE: To examine associations of Abeta and brain microstructure with cognitive decline in amnestic mild cognitive impairment and dementia. METHODS: Restriction spectrum imaging, cerebrospinal fluid Abeta, and longitudinal cognitive data were collected on 23 healthy controls and 13 individu...
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#1Emilie T. ReasH-Index: 13
#2Donald J. HaglerH-Index: 90
Last. James B. BrewerH-Index: 54
view all 11 authors...
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#1Piotr Sowa (Oslo University Hospital)H-Index: 6
#2Hanne F. Harbo (Oslo University Hospital)H-Index: 55
Last. Mona K. Beyer (HiOA: Oslo and Akershus University College of Applied Sciences)H-Index: 30
view all 12 authors...
Background:Restriction spectrum imaging (RSI) is a recently introduced magnetic resonance imaging diffusion technique. The utility of RSI in multiple sclerosis (MS) is unknown.Objective:To investigate the association between RSI-derived parameters and neurological disability in MS.Methods:Seventy-seven relapsing–remitting MS patients were scanned with RSI on a 3-T scanner. RSI-derived parameters: fast and slow apparent diffusion coefficient (sADC), fractional anisotropy, restricted fractional an...
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#1Roshan Karunamuni (UCSD: University of California, San Diego)H-Index: 17
#2Nathan S. White (UCSD: University of California, San Diego)H-Index: 28
Last. Leif Oltedal (University of Bergen)H-Index: 15
view all 7 authors...
BackgroundThe utility of incorporating both diffusion information and T2 relaxation times in the imaging work-up of stroke patients is being investigated in a number of clinical trials and scientif...
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#1Usman A. Khan (UCSD: University of California, San Diego)H-Index: 44
#2Robert C. Rennert (UCSD: University of California, San Diego)H-Index: 31
Last. Clark C. Chen (UMN: University of Minnesota)H-Index: 57
view all 7 authors...
Abstract Discriminating between tumor recurrence and treatment effects in glioblastoma patients undergoing radiation-temozolomide (RT/TMZ) therapy remains a major clinical challenge. Here, we report a pilot study to determine the utility of restriction spectrum imaging (RSI), an advanced diffusion-weighted MRI (DWI) technique that affords meso-scale resolution of cell density, in this assessment. A retrospective review of 31 patients with glioblastoma treated between 2011 and 2017 who underwent ...
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#1Naeim Bahrami (UCSD: University of California, San Diego)H-Index: 12
#2Stephen J. Hartman (UCSD: University of California, San Diego)H-Index: 2
Last. Carrie R. McDonald (UCSD: University of California, San Diego)H-Index: 39
view all 12 authors...
Background Molecular markers of WHO grade II/III glioma are known to have important prognostic and predictive implications and may be associated with unique imaging phenotypes. The purpose of this study is to determine whether three clinically relevant molecular markers identified in gliomas—IDH, 1p/19q, and MGMT status—show distinct quantitative MRI characteristics on FLAIR imaging.
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#1Naeim BahramiH-Index: 12
#2David PiccioniH-Index: 23
Last. Carrie R. McDonaldH-Index: 39
view all 11 authors...
BACKGROUND AND PURPOSE: Treatment with bevacizumab is standard of care for recurrent high-grade gliomas; however, monitoring response to treatment following bevacizumab remains a challenge. The purpose of this study was to determine whether quantifying the sharpness of the fluid-attenuated inversion recovery hyperintense border using a measure derived from texture analysis—edge contrast—improves the evaluation of response to bevacizumab in patients with high-grade gliomas. MATERIALS AND METHODS:...
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#1Roshan Karunamuni (UCSD: University of California, San Diego)H-Index: 17
#2Joshua M. Kuperman (UCSD: University of California, San Diego)H-Index: 27
Last. Nathan S. White (UCSD: University of California, San Diego)H-Index: 28
view all 11 authors...
BackgroundHigh b-value diffusion-weighted imaging has application in the detection of cancerous tissue across multiple body sites. Diffusional kurtosis and bi-exponential modeling are two popular model-based techniques, whose performance in relation to each other has yet to be fully explored.PurposeTo determine the relationship between excess kurtosis and signal fractions derived from bi-exponential modeling in the detection of suspicious prostate lesions.Material and MethodsThis retrospective s...
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