Taeun Chang
George Washington University
Internal medicineSurgeryMagnetic resonance imagingCardiologyNeurointensive carePediatricsProspective cohort studyHypothermiaNeonatal encephalopathyEpilepsyGestational ageEncephalopathyNeonatal seizurePopulationHypoxic Ischemic EncephalopathyIntensive careAnesthesiaGestationElectroencephalographyMedicineCohort
Publications 119
#1Khorshid Mohammad (U of C: University of Calgary)H-Index: 8
#2Alexa Craig (Maine Medical Center)H-Index: 5
Last. Lena Hellström-Westas (Uppsala University)H-Index: 57
view all 15 authors...
Background null Neonatal neurocritical care (NNCC) is a rapidly advancing field with limited fellowship training available in locally developed, non-accredited programs. A standardized survey aimed to understand the training backgrounds of individuals practicing NNCC, the structure of existing clinical NNCC services/training programs, and suggested clinical competencies for new graduates. null Methods null We developed an anonymous survey electronically sent to members of societies related to NN...
#2Janette Mailo (Glenrose Rehabilitation Hospital)
Last. Taeun Chang (GW: George Washington University)H-Index: 30
view all 10 authors...
Neonatal encephalopathy (NE) is the most common etiology of acute neonatal seizures - about half of neonates treated with therapeutic hypothermia for NE have EEG-confirmed seizures. These seizures are best identified with continuous EEG monitoring, as clinical diagnosis leads to under-diagnosis of subclinical seizures and over-treatment of events that are not seizures. High seizure burden, especially status epilepticus, is thought to augment brain injury. Treatment, therefore, is aimed at minimi...
1 CitationsSource
#1Elliott Mark Weiss (UW: University of Washington)H-Index: 3
#2Katherine Guttmann (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 2
Last. Kaashif A. Ahmad (BCM: Baylor College of Medicine)H-Index: 9
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Objective null To describe the parental experience of recruitment and assess differences between parents who participated and those who declined to enroll in a neonatal clinical trial. null null null Study design null This was a survey conducted at 12 US neonatal intensive care units of parents of infants who enrolled in the High-dose Erythropoietin for Asphyxia and encephaLopathy (HEAL) trial or who were eligible but declined enrollment. Questions assessed 6 factors of the parental experience o...
#1A.G. Sandoval Karamian (Children's Hospital of Philadelphia)
#2S. Mercimek-Andrews (U of A: University of Alberta)
Last. Courtney J. Wusthoff (Stanford University)H-Index: 28
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Neonatal encephalopathy (NE) describes the clinical syndrome of a newborn with abnormal brain function that may result from a variety of etiologies. HIE should be distinguished from neonatal encephalopathy due to other causes using data gathered from the history, physical and neurological exam, and further investigations. Identifying the underlying cause of encephalopathy has important treatment implications. This review outlines conditions that cause NE and may be mistaken for HIE, along with t...
Background/objective Near-infrared spectroscopy (NIRS)-based measures of cerebral autoregulation (CAR) can potentially identify neonates with hypoxic-ischemic encephalopathy (HIE) who are at greatest risk of irreversible brain injury. However, modest predictive abilities have precluded previously described metrics from entering clinical care. We previously validated a novel autoregulation metric in a piglet model of induced hypotension called the hemoglobin volume phase index (HVP). The objectiv...
1 CitationsSource
#1Monica E. Lemmon (Duke University)H-Index: 14
#2Hannah C. Glass (UCSF: University of California, San Francisco)H-Index: 37
Last. Taeun Chang (GW: George Washington University)H-Index: 30
view all 19 authors...
Abstract null null Purpose null Parents of neonates with seizures are at risk of mental health symptoms due to the impact of illness on family life, prognostic uncertainty, and the emotional toll of hospitalization. A family-centered approach is the preferred model to mitigate these challenges. We aimed to identify strategies to promote family-centered care through an analysis of parent-offered advice to clinicians caring for neonates with seizures. null null null Basic procedures null This pros...
#1Renée A. Shellhaas (UM: University of Michigan)H-Index: 32
#2Courtney J. Wusthoff (Stanford University)H-Index: 28
Last. Cameron Thomas (UC: University of Cincinnati)H-Index: 8
view all 16 authors...
OBJECTIVE We aimed to evaluate early-life epilepsy incidence, seizure types, severity, risk factors, and treatments among survivors of acute neonatal seizures. METHODS Neonates with acute symptomatic seizures born 7/2015-3/2018 were prospectively enrolled at nine Neonatal Seizure Registry sites. One-hour EEG was recorded at age three months. Post-neonatal epilepsy and functional development (Warner Initial Developmental Evaluation of Adaptive and Functional Skills - WIDEA-FS) were assessed. Cox ...
#1Hannah C. Glass (UCSF: University of California, San Francisco)H-Index: 37
#2Janet S. Soul (Boston Children's Hospital)H-Index: 37
Last. Renée A. Shellhaas (UM: University of Michigan)H-Index: 32
view all 17 authors...
Importance Antiseizure medication (ASM) treatment duration for acute symptomatic neonatal seizures is variable. A randomized clinical trial of phenobarbital compared with placebo after resolution of acute symptomatic seizures closed early owing to low enrollment. Objective To assess whether ASM discontinuation after resolution of acute symptomatic neonatal seizures and before hospital discharge is associated with functional neurodevelopment or risk of epilepsy at age 24 months. Design, Setting, ...
4 CitationsSource
#1Lina F. Chalak (UTSW: University of Texas Southwestern Medical Center)H-Index: 24
#2Raymond W. Redline (University Hospitals of Cleveland)H-Index: 65
Last. Ellen M. Bendel-Stenzel (Mayo Clinic)H-Index: 7
view all 25 authors...
OBJECTIVE To examine the frequency of placental abnormalities in a multicenter cohort of newborn infants with hypoxic-ischemic encephalopathy (HIE), and to determine the association between acuity of placental abnormalities and clinical characteristics of HIE. STUDY DESIGN Infants born at ≥ 36 weeks of gestation (n=500) with moderate or severe HIE were enrolled in the High-dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) Trial. A placental pathologist blinded to clinical information re...
1 CitationsSource