Donald J. Hagler
University of California, San Diego
AnatomyInternal medicineRadiologySurgeryMagnetic resonance imagingDiffusion MRIPsychologyCardiologyNeuroscienceCognitionHemodynamicsCardiac catheterizationVentricleHeart diseasePercutaneousPulmonary arteryTemporal lobeWhite matterBrain mappingMagnetoencephalographyNeuroimagingMedicineBiology
Publications 441
#1Nathaniel W. Taggart (Mayo Clinic)H-Index: 14
#2Guy S. Reeder (Mayo Clinic)H-Index: 72
Last. Donald J. Hagler (Mayo Clinic)H-Index: 89
view all 8 authors...
Objectives To describe medium- to long-term follow-up of patients undergoing device closure of patent foramen ovale (PFO) for stroke or transient ischemic attack (TIA). Background Transcatheter device closure of PFO continues to be used for secondary prevention of cryptogenic stroke or TIA, but data are lacking regarding long-term outcomes. Methods We reviewed the Mayo Clinic Rochester PFO database for patients who underwent device closure of PFO for secondary prevention of stroke/TIA from Decem...
13 CitationsSource
#1Mohamad Alkhouli (Mayo Clinic)H-Index: 23
#2Mohammad Sarraf (Mayo Clinic)H-Index: 7
Last. Charanjit S. Rihal (Mayo Clinic)H-Index: 96
view all 10 authors...
Abstract Objectives The aim of this study is to provide a summary of the currently applied aortic paravalvular leak (PVL) closure techniques and describe the procedural and long-term outcomes in a large consecutive cohort of patients. Background Percutaneous repair has emerged as an effective therapy for patients with PVL. To date, clinical outcome data on percutaneous closure of aortic PVL are limited. Methods All patients who underwent catheter-based treatment of aortic PVL between 2006 and 20...
33 CitationsSource
#1Richard Q. Loi (UCSD: University of California, San Diego)H-Index: 4
#2Kelly M. Leyden (UCSD: University of California, San Diego)H-Index: 10
Last. Carrie R. McDonald (UCSD: University of California, San Diego)H-Index: 37
view all 9 authors...
SummaryObjective Diffusion tensor imaging (DTI) has become a popular tool for delineating the location and extent of white matter injury in temporal lobe epilepsy (TLE). However, DTI yields nonspecific measures that are confounded by changes occurring within both the intracellular and extracellular environments. This study investigated whether an advanced diffusion method, restriction spectrum imaging (RSI) could provide a more robust measure of white matter injury in TLE relative to DTI due to ...
9 CitationsSource
#1Hana Uhlirova (UCSD: University of California, San Diego)H-Index: 6
#2Kıvılcım Kılıç (UCSD: University of California, San Diego)H-Index: 11
Last. Anna Devor (UCSD: University of California, San Diego)H-Index: 38
view all 23 authors...
The computational properties of the human brain arise from an intricate interplay between billions of neurons connected in complex networks. However, our ability to study these networks in healthy human brain is limited by the necessity to use non-invasive technologies. This is in contrast to animal models where a rich, detailed view of cellular-level brain function with cell-type-specific molecular identity has become available due to recent advances in microscopic optical imaging and genetics....
32 CitationsSource
#1Mohamad Alkhouli (Mayo Clinic)H-Index: 23
#2Abdallah El Sabbagh (Mayo Clinic)H-Index: 11
Last. Mackram F. Eleid (Mayo Clinic)H-Index: 33
view all 6 authors...
Significant residual mitral regurgitation (MR) may persist after MitraClip (Abbott Vascular, Santa Clara, California) implantation in up to 7% of patients with degenerative MR [(1)][1]. Treatment of the residual MR with an adjacent MitraClip may not be feasible, because of commissural location,
3 CitationsSource
Key Points: Current delivery systems for the Sapien XT valve for the native pulmonary valve are unacceptable stiff and poorly design for implantation in the pulmonary outflow tract. This report details improvisation of the Melody Ensemble for easier pulmonary outflow tract delivery of the Sapien XT valve. The unacceptable cost of the utilization of two delivery systems for valve implantation, requires industry development of an safe, effective delivery system appropriate for the pulmonary outflo...
#1Kristine B. Walhovd (University of Oslo)H-Index: 78
#2Stine Kleppe Krogsrud (University of Oslo)H-Index: 10
Last. Anders M. Fjell (University of Oslo)H-Index: 79
view all 22 authors...
Neurodevelopmental origins of functional variation in older age are increasingly being acknowledged, but identification of how early factors impact human brain and cognition throughout life has rem ...
102 CitationsSource
#1Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 71
view all 11 authors...
#1Erik Newman (UCSD: University of California, San Diego)H-Index: 10
#2Wesley K. Thompson (UCSD: University of California, San Diego)H-Index: 71
Last. Terry L. Jernigan (UCSD: University of California, San Diego)H-Index: 101
view all 27 authors...
Anxiety is a risk factor for many adverse neuropsychiatric and socioeconomic outcomes, and has been linked to functional and structural changes in the ventromedial prefrontal cortex (VMPFC). However, the nature of these differences, as well as how they develop in children and adolescents, remains poorly understood. More effective interventions to minimize the negative consequences of anxiety require better understanding of its neurobiology in children. Recent research suggests that structural im...
29 CitationsSource
#1Chun C. Fan (UCSD: University of California, San Diego)H-Index: 8
#1Chun Chieh Fan (UCSD: University of California, San Diego)H-Index: 26
Last. Anders M. Dale (UCSD: University of California, San Diego)H-Index: 165
view all 8 authors...
Williams Syndrome (WS), a rare genetic disorders caused by hemizyous deletion of ~26 genes on the chromosome 7, has unique cognitive features and neuroanatomic abnormalities. Limited in statistical power due to its rareness had led to inconsistent in many direct comparisons using structural magnetic resonance imaging (MRI), and their associations with cognitive features of WS are not clear. Here, we used a novel approach to derive a WS specific neuroarchitectural profile and tested its associati...