Tooru Shimosegawa
Tohoku University
CancerEndocrinologySurgeryPathologyHepatic stellate cellChemistryImmunologyPancreatitisHelicobacter pyloriAcute pancreatitisGastric acidAutoimmune pancreatitisPancreasPancreatic cancerHepatologyCancer researchMedicineBiologyGastroenterologyCell biology
910Publications
69H-index
20.4kCitations
Publications 947
Newest
#1Hiroshi Nagai (Tohoku University)H-Index: 32
#2Masatake Kuroha (Tohoku University)H-Index: 11
Last. Atsushi Masamune (Tohoku University)H-Index: 53
view all 15 authors...
INTRODUCTION Exosomes are membrane-enclosed nanovesicles, which are increasingly being recognized as important cell communication components for their role in transmitting microRNAs (miRNAs). No previous study has addressed the exosomal miRNA profile in colorectal adenomas (CRAs) because the long-term culture of CRA is challenging. This study aimed to identify the miRNA signature in organoid exosomes derived from human CRA and colorectal cancer (CRC) samples. METHODS Organoid cultures were devel...
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#1Yasuhiro Takikawa (Iwate Medical University)H-Index: 25
#2Keisuke Kakisaka (Iwate Medical University)H-Index: 10
Last. Tooru ShimosegawaH-Index: 69
view all 8 authors...
3 CitationsSource
#1Fumiko ShimodaH-Index: 1
#2Akihiko SatohH-Index: 28
Last. Tooru ShimosegawaH-Index: 69
view all 5 authors...
Situs inversus totalis (SIT) is a rare congenital anomaly in which all viscera are transposed to the opposite side of the body. This uncommon anatomy causes technical difficulties in endoscopic treatment. A 98-year-old woman with SIT was admitted to our hospital complaining of upper abdominal pain and fever. Blood examinations and findings of abdominal computed tomography imaging confirmed the diagnosis of acute pancreatitis and cholangitis associated with biliary stones. After recovering from p...
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#1Kazuaki Norita (Tohoku University)H-Index: 1
#2Tomoyuki Koike (Tohoku University)H-Index: 26
Last. Katsunori Iijima (Akita University)H-Index: 25
view all 22 authors...
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#2Osamu KimuraH-Index: 15
Last. Tooru ShimosegawaH-Index: 69
view all 10 authors...
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#1Kazuaki Norita (Tohoku University)H-Index: 1
#2Kiyotaka Asanuma (Tohoku University)H-Index: 11
Last. Atsushi Masamune (Tohoku University)H-Index: 53
view all 15 authors...
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#1Masatake Kuroha (Tohoku University)H-Index: 11
#2Hisashi Shiga (Tohoku University)H-Index: 3
Last. Atsushi Masamune (Tohoku University)H-Index: 53
view all 15 authors...
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#1Atsushi Masamune (Tohoku University)H-Index: 53
#3Kazuhiro Kikuta (Tohoku University)H-Index: 35
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 68
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OBJECTIVES To provide updated clinico-epidemiological information on chronic pancreatitis (CP) in Japan. METHODS We conducted a two-stage nationwide epidemiological survey; the number of CP patients was estimated in the first-stage survey, and their clinical features were examined in the second-stage survey. We surveyed patients with CP who had visited hospitals in 2016 and were diagnosed according to the Japanese diagnostic criteria 2009 (DC2009). Furthermore, we validated the new Japanese diag...
2 CitationsSource
#1William Greenhalf (University of Liverpool)H-Index: 39
#2Philippe Lévy (University of Paris)H-Index: 26
Last. John P. Neoptolemos (Heidelberg University)H-Index: 99
view all 26 authors...
Abstract Background Patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer. We present the international consensus guidelines for surveillance of pancreatic cancer in CP. Methods The international group evaluated 10 statements generated from evidence on 5 questions relating to pancreatic cancer in CP. The GRADE approach was used to evaluate the level of evidence available per statement. The working group voted on each statement for strength of agreement, using a nine...
2 CitationsSource
#1Yi Miao (Nanjing Medical University)H-Index: 5
#1Yi Miao (Nanjing Medical University)H-Index: 1
Last. Markus W. Büchler (Heidelberg University)H-Index: 134
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Abstract Background The aim was to evaluate the various operative techniques and outcomes used to manage the pancreatic transection plane (or stump) during a left (distal) pancreatectomy and to develop expert consensus guidelines. Methods Evidence-based, clinically relevant questions were discussed and then were circulated among members of the International Study Group of Pancreatic Surgery. After agreement on the questions and statements, voting in a 9-point Likert scale was used to gauge the l...
9 CitationsSource