Christoph Abé
Karolinska Institutet
PsychiatryPolysubstance dependenceInternal medicineEndocrinologyMagnetic resonance imagingPsychologyCardiologyNeuroscienceCognitionNeurocognitiveBipolar disorderMetaboliteAnterior cingulate cortexAlcohol dependenceWhite matterPopulationNeuroimagingClinical psychologyMedicineBiology
54Publications
18H-index
1,424Citations
Publications 46
Newest
#1Sean R. McWhinney (Dal: Dalhousie University)H-Index: 6
#2Christoph Abé (KI: Karolinska Institutet)H-Index: 18
Last. Tomas Hajek (Dal: Dalhousie University)H-Index: 37
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Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated with neurostructural alterations. Yet, the effects of obesity on brain structure in BD are under-researched. We obtained MRI-derived brain subcortical volumes and body mass index (BMI) from 1134 BD and 1601 control individuals from 17 independent research sites within the ENIGMA-BD Working Group. We jointly modeled the effects of BD and BMI on subcortical volumes using mixed-effects modeling and tes...
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#1Christoph Abé (KI: Karolinska Institutet)H-Index: 18
#2Alexander V. Lebedev (KI: Karolinska Institutet)H-Index: 13
Last. Qazi Rahman ('KCL': King's College London)H-Index: 29
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Genetic and hormonal factors have been suggested to influence human sexual orientation. Previous studied proposed brain differences related to sexual orientation and that these follow cross-sex shifted patterns. However, the neurobiological correlates of sexual orientation and how genetic factors relate to brain structural variation remains largely unexplored. Using the largest neuroimaging-genetics dataset available on same-sex sexual behavior (SSB) (n = 18,645), we employed a data-driven multi...
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#1Christoph Abé (KI: Karolinska Institutet)H-Index: 18
#2Roberth Adebahr (Umeå University)H-Index: 1
Last. Christoffer Rahm (KI: Karolinska Institutet)H-Index: 8
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Objective Pedophilic disorder (PD) is characterized by persistent sexual interest in prepubertal children causing distress and increasing the risk for child sexual abuse. Although prior research suggests that PD has neurodevelopmental underpinnings, the evidence remains sparse. To aid the understanding of etiology and treatment development, we quantified neurobiological and clinical correlates of PD. Method We compared 55 self-referred, help-seeking, non-forensic male patients with DSM-5 PD with...
1 CitationsSource
#1Yash Patel (U of T: University of Toronto)H-Index: 5
#2Hyperactivity Disorder (U of T: University of Toronto)H-Index: 1
Last. Tomáš Paus (U of T: University of Toronto)H-Index: 108
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Importance Large-scale neuroimaging studies have revealed group differences in cortical thickness across many psychiatric disorders. The underlying neurobiology behind these differences is not well understood. Objective To determine neurobiologic correlates of group differences in cortical thickness between cases and controls in 6 disorders: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), major depressive disorder (MDD), obsessive-compulsiv...
16 CitationsSource
#1Christoph AbéH-Index: 18
#2Roberth AdebahrH-Index: 1
Last. Christoffer RahmH-Index: 8
view all 8 authors...
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#1Frida Bayard (KI: Karolinska Institutet)H-Index: 3
#2Charlotte Nymberg Thunell (KI: Karolinska Institutet)H-Index: 1
Last. Predrag Petrovic (KI: Karolinska Institutet)H-Index: 35
view all 37 authors...
Attention-Deficit/Hyperactivity Disorder (ADHD) and conduct disorder (CD) exemplify top-down dysregulation conditions that show a large comorbidity and shared genetics. At the same time, they entail two different types of symptomology involving mainly non-emotional or emotional dysregulation. Few studies have tried to separate the specific biology underlying these two dimensions. It has also been suggested that both types of conditions consist of extreme cases in the general population where the...
10 CitationsSource
#1Alexander V. Lebedev (KI: Karolinska Institutet)H-Index: 13
#2Christoph Abé (KI: Karolinska Institutet)H-Index: 18
Last. Predrag Petrovic (KI: Karolinska Institutet)H-Index: 35
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Summary A number of previous studies have indicated that market and population well-being are related. Using UK-biobank data we first identified a significant association between a local stock market index (FTSE100) and mood of 479,791 subjects and demonstrated that FTSE100 exhibits significant associations with volumetric measures of the brain regions involved in affective processing in 39,755 subjects with more distant markets exhibiting a weaker relation to these regions. These effects were p...
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#2Christoph AbéH-Index: 18
Last. Predrag PetrovicH-Index: 35
view all 6 authors...
Summary Previous research suggests that market and population well-being are related 1–7. However, the underlying mechanisms remain unclear. Using UK-biobank data we confirmed a significant association between a local stock market index (FTSE100) and mood of 479,791 subjects, and demonstrated that FTSE100 exhibits significant association with volumetric measures of the brain regions involved in affective processing in 39,755 subjects. Market decline (lower index scores) was associated with large...
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#1Alexander V. Lebedev (KI: Karolinska Institutet)H-Index: 13
#2Christoph Abé (KI: Karolinska Institutet)H-Index: 18
Last. Predrag Petrovic (KI: Karolinska Institutet)H-Index: 35
view all 7 authors...
The stock market is a bellwether of socio-economic changes that may directly affect individual well-being. Using large-scale UK-biobank data generated over 14 years, we applied specification curve analysis to rigorously identify significant associations between the local stock market index (FTSE100) and 479,791 UK residents9 mood, as well as their alcohol intake and blood pressure adjusting the results for a large number of potential confounders, including age, sex, linear and non-linear effects...
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#1Frida Bayard (KI: Karolinska Institutet)H-Index: 3
#2Christoph Abé (KI: Karolinska Institutet)H-Index: 18
Last. Predrag Petrovic (KI: Karolinska Institutet)H-Index: 35
view all 6 authors...
Both non-emotional symptoms, such as inattention, and symptoms of emotional instability (EI) are partially co-varying and normally distributed in the general population. ADHD, which is associated with both inattention and emotional instability, has been related to lower reward anticipation activation in ventral striatum. However, it is not known whether non-emotional dysregulation, such as inattention, or EI – or both – are associated with this effect. We hypothesized that altered reward process...
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