Masahiko Takahata
Hokkaido University
AnatomyInternal medicineEndocrinologySurgeryMagnetic resonance imagingRetrospective cohort studyBone remodelingChemistryMaterials scienceOsteoporosisBone mineralTeriparatideRheumatoid arthritisMyelopathyOssificationKyphosisSpinal fusionRadiographyBone resorptionOrthopedic surgeryMedicine
159Publications
30H-index
2,126Citations
Publications 168
Newest
#1Satoru EgawaH-Index: 6
#2Toshitaka YoshiiH-Index: 26
Last. Yukitaka NagamotoH-Index: 14
view all 21 authors...
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#1Shunichi Yokota (Hokkaido University)H-Index: 1
#2Gen Matsumae (Hokkaido University)H-Index: 2
Last. Masahiko Takahata (Hokkaido University)H-Index: 30
view all 13 authors...
Abstract null null A growing body of evidence suggests that immune factors that regulate osteoclast differentiation and bone resorption might be promising therapeutic agents for the treatment of osteoporosis. The expression of CLCF1, an immune cell-derived molecule, has been reported to be reduced in patients with postmenopausal osteoporosis. This suggests that it may be involved in bone remodeling. Thus, we explored the functional role of CLCF1 in osteoclastogenesis and bone loss associated wit...
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#1Masao KodaH-Index: 38
#2Toshitaka YoshiiH-Index: 26
Last. Atsushi KimuraH-Index: 19
view all 45 authors...
Postoperative neck pain has been reported as an unsolved postoperative complication of surgery for cervical ossification of the posterior longitudinal ligament (OPLL). The aim of the present study was to elucidate factors having a significant association with postoperative deterioration of neck pain in cervical OPLL patients. We studied a cohort of patients in a prospective registry of 478 patients who had undergone cervical spine surgery for cervical OPLL. We excluded those without evaluation o...
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#1Tsutomu Endo (Hokkaido University)H-Index: 6
#2Yoshinao Koike (Hokkaido University)H-Index: 3
Last. Masahiko Takahata (Hokkaido University)H-Index: 30
view all 16 authors...
Study Design:Retrospective cross-sectional study.Objectives:There is insufficient data on the clinical features of ossification of the ligamentum flavum (OLF) of the thoracic spine and the risk of ...
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#1Tomomaya Yamamoto (Hokkaido University)H-Index: 10
#2Tomoka Hasegawa (Hokkaido University)H-Index: 20
Last. Keisuke Kubota (Hokkaido University)
view all 17 authors...
Modeling, the changes of bone size and shape, often takes place at the developmental stages, whereas bone remodeling-replacing old bone with new bone-predominantly occurs in adults. Unlike bone remodeling, bone formation induced by modeling i.e., minimodeling (microscopic modeling in cancellous bone) is independent of osteoclastic bone resorption. Although recently-developed drugs for osteoporotic treatment could induce minimodeling-based bone formation in addition to remodeling-based bone forma...
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#1Ryota Suzuki (Hokkaido University)H-Index: 1
#2Yoshinao Koike (Hokkaido University)H-Index: 3
Last. Akira Iwata (Hokkaido University)H-Index: 10
view all 13 authors...
Objective null To identify risk factors for significant blood loss (SBL) in cervical laminoplasty, especially regarding thrombocytopenia and coagulopathy resulting from non-alcoholic fatty liver disease (NAFLD). null null null Methods null We retrospectively investigated differences in patient background data, laboratory data at the time of admission, and surgery-related data of 317 patients who underwent cervical laminoplasty and were divided into SBL (estimated blood loss [EBL] + drainage [D] ...
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#1Ryota HyakkanH-Index: 2
#2Masahiro KanayamaH-Index: 28
Last. Masahiko Takahata (Hokkaido University)H-Index: 30
view all 3 authors...
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#1Tsutomu Endo (Hokkaido University)H-Index: 6
#2Yoshinao Koike (Hokkaido University)H-Index: 3
Last. Yuichi HasegawaH-Index: 1
view all 19 authors...
Ossification of the posterior longitudinal ligament (OPLL) of the spine is a disease of unknown etiology occurring frequently in individuals with metabolic disturbances. Obesity has been suggested as a potential risk factor for the severity of OPLL. We aimed to investigate whether non-alcoholic fatty liver disease (NAFLD) is associated with OPLL severity. We assessed the severity of NAFLD by a liver-to-spleen (L/S) ratio on computed tomography (CT) scans of 85 symptomatic OPLL patients at a sing...
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It remains unknown whether the histology of vascular invasion during secondary ossification of epiphyseal cartilage is the same as that seen in primary ossification; we examined the initial processes of vascular invasion of secondary ossification in the murine femora. Many endomucin-immunoreactive blood vessels gathered at the central region of the articular surface, and buds of soft tissue, including glomerular loops of endomucin-immunoreactive blood vessels and TNALPase- immunopositive osteobl...
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#1Toshitaka YoshiiH-Index: 26
#2Satoru EgawaH-Index: 6
Last. Atsushi KimuraH-Index: 19
view all 37 authors...
Study design null This was a prospective multicenter study. null Objective null The aim of this study was to investigate the perioperative complications of posterior surgeries for the treatment of cervical ossification of the posterior longitudinal ligament (OPLL). null Summary of background data null Surgical treatment for cervical OPLL has a high risk of various complications. Laminoplasty (LAMP) and posterior decompression and instrumented fusion (PDF) are effective for multilevel cervical OP...
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