Hiroaki Mita
Sapporo Medical University
Gene silencingCancerInternal medicineSurgeryPathologyMolecular biologyDNA methylationCarcinomaStomachCHFRPercutaneous endoscopic gastrostomyMethylationTranscription (biology)EpigeneticsCancer researchCarcinogenesisHistoneMedicineBiologyGastroenterologyMitosisCancer cell
52Publications
19H-index
1,585Citations
Publications 52
Newest
#1Hiroaki MitaH-Index: 19
#2Yasushi AdachiH-Index: 34
Last. Takao EndoH-Index: 22
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#1Hideaki Takahashi (St. Marianna University School of Medicine)H-Index: 11
#1Hideaki Takahashi (St. Marianna University School of Medicine)
Last. Takao EndoH-Index: 22
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We herein report a rare case of intraductal papillary mucinous neoplasm with a pancreatogastric fistula in an elderly Japanese man admitted to our hospital. The pancreatogastric fistula was confirmed using endoscopic retrograde pancreatography via a cannulated guidewire placed in the stomach. Six months after admission, the patient was diagnosed with intraductal papillary mucinous carcinoma. A pancreatogastric fistula is generally a rare complication of intraductal papillary mucinous neoplasm. I...
Source
#1Norikazu IwataH-Index: 1
#2Yoshifumi IshiiH-Index: 4
Last. Takao EndoH-Index: 22
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A male patient in his 70s underwent a right lobectomy because of a hepatocellular carcinoma(HCC)located in the right lobe(S6)of his liver. Eleven months after surgery, contrast-enhanced CT showed multiple masses in the residual liver, which were diagnosed as HCC recurrence. He was then treated with hepatic arterial infusion chemotherapy(HAIC). Ten months after the recurrence, the liver tumors progressed. Therefore, treatment was switched to sorafenib(400 mg/day orally)and HAIC(low-dose FP: 5-FU ...
#1Yukinari YoshidaH-Index: 9
#2Hiroaki TakahashiH-Index: 20
Last. Takao EndoH-Index: 22
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We report a rare case of undifferentiated-type intramucosal gastric cancer that occurred in the fornix of the stomach without Helicobacter pylori infection, which consisted mainly of poorly differentiated adenocarcinoma. A 49-year-old man visited our hospital for a follow-up endoscopic examination of a small depressed lesion of the gastric fornix detected by surveillance esophagogastroduodenoscopy. On magnifying endoscopy with blue laser imaging, the depressed lesion (approximately 10 mm in diam...
1 CitationsSource
#1Yasuyo AdachiH-Index: 1
#1Yasuyo AdachiH-Index: 1
Last. Takao EndoH-Index: 22
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IgG4-related autoimmune hepatitis (IgG4-AIH) is characterized by hepatic inflammation and is considered an IgG4-related disease. Several inflammatory pseudotumors (IPTs) are also considered as IgG4-related diseases;however, there have been no reports of cases wherein both diseases occurred concurrently. An older adult with liver dysfunction was admitted to the hospital and was diagnosed with IgG4-AIH following a liver biopsy;IgG4-positive plasma cell infiltration in the portal tract and high ser...
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#1Yukinari YoshidaH-Index: 9
#2Takashi SibusaH-Index: 1
Last. Takao EndoH-Index: 22
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A rare case of lung cancer with the simultaneous production of granulocyte colony-stimulating factor (G-CSF) and interleukin-6 (IL-6) is reported. A 79-year-old man was admitted to our hospital due to cachectic symptoms and an increased inflammatory response. Laboratory tests and imaging studies suggested metastatic lung cancer with high serum levels of G-CSF and IL-6. He died of progressive disease, and an autopsy showed that the lung tumor had positive protein expression of both cytokines and ...
3 CitationsSource
#1Toshiyuki Kubo (Sapporo Medical University)H-Index: 4
#2Yasushi Adachi (Sapporo Medical University)H-Index: 49
Last. Takao EndoH-Index: 22
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1 CitationsSource
#1Yasushi AdachiH-Index: 34
#1Yasushi AdachiH-Index: 49
Last. Takao EndoH-Index: 22
view all 11 authors...
: Paraganglioma and pheochromocytoma are rare neuroendocrine neoplasms that originate from chromaffin cells. In many of these tumors, several mutations are reported to occur in the genes of germline and/or somatic cells. A case of paraganglioma in the posterior mediastinum with highly malignant potential is reported. The patient had a rapid clinical course, and it was difficult to reach the final diagnosis. The initial diagnosis on fine-needle aspiration biopsy was a gastrointestinal stromal tum...
1 CitationsSource
Background: Although percutaneous endoscopic gastrostomy (PEG) is a well-accepted and less invasive method of feeding tube placement in patients with swallowing difficulties, complications and early death after PEG have been reported. Aim: This study aimed to evaluate predictive factors associated with 30-day mortality after PEG, and to assess the utility of nutritional supporting period before PEG in reducing early mortality following PEG. Design: An observational study. Methods: We retrospecti...
1 CitationsSource
#1Yukinari YoshidaH-Index: 9
#2Takao EndoH-Index: 22
Last. Yasuo KatoH-Index: 6
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We herein report the case of a 78-year-old woman with an intraductal tumor with scant mucin production in a moderately dilated main pancreatic duct that resembled an intraductal tubulopapillary neoplasm (ITPN) on imaging. An endoscopic transpapillary forceps biopsy enabled an accurate preoperative diagnosis of the tumor as an oncocytic type intraductal papillary mucinous neoplasm (IPMN) of the pancreas microscopically showing papillary growth consisting of oncocytic cells with a typical mucin ex...
1 CitationsSource