Nobukazu Ishizaka
Osaka Medical College
Angiotensin II receptor type 1RadiologyEndocrinologyPathologyOdds ratioRenal functionCardiologyChemistryRenin–angiotensin systemHeart failureCoronary artery diseaseKidney diseaseKidneyMetabolic syndromeAngiotensin IIRisk factorQuartileMedicineEjection fractionBlood pressure
Publications 302
#1Hisanori UmeharaH-Index: 43
#2Kazuichi Okazaki (Kansai Medical University)H-Index: 68
Last. Mitsuhiro Kawano (Kanazawa University)H-Index: 20
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1 CitationsSource
#1Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
#1Atsushi Tanaka (Saga University)H-Index: 18
#2Isao Taguchi (Dokkyo Medical University)H-Index: 15
Last. Koichi Node (Saga University)H-Index: 45
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BACKGROUND: An elevated level of serum uric acid (SUA) is associated with an increased risk of cardiovascular disease. Pharmacological intervention with urate-lowering agents, such as the conventional purine analogue xanthine oxidase (XO) inhibitor, allopurinol, has been used widely for a long period of time in clinical practice to reduce SUA levels. Febuxostat, a novel non-purine selective inhibitor of XO, has higher potency for inhibition of XO activity and greater urate-lowering efficacy than...
6 CitationsSource
#1Ichiro Hisatome (Tottori University)H-Index: 39
#2Kimiyoshi Ichida (Tokyo University of Pharmacy and Life Sciences)H-Index: 32
Last. Tetsuya YamamotoH-Index: 38
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1 CitationsSource
#1Ichiro Mizushima (Kanazawa University)H-Index: 12
#2Satomi Kasashima (Kanazawa University)H-Index: 21
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
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: IgG4-related disease is a systemic disease, characterized by elevation of serum IgG4 and, histopathologically, massive infiltration of IgG4+ lymphocyte and plasma cell infiltration, storiform fibrosis, causing enlargement, nodules or thickening. It may affect various organs simultaneously or metachronously. Here we analyzed the clinical and pathological characteristics of 99 patients diagnosed with IgG4-related periaortitis/periarteritis and retroperitoneal fibrosis. Of 99 patients (women/men,...
9 CitationsSource
#1Fumio Terasaki (Osaka Medical College)H-Index: 26
#2Arata Azuma (Nippon Medical School)H-Index: 44
Last. Akira Yamashina (TMU: Tokyo Medical University)H-Index: 44
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28 CitationsSource
#1Ryo Yokoyama (Osaka Medical College)H-Index: 3
#2Masaaki (Osaka Medical College)H-Index: 18
Last. Michio Asahi (Osaka Medical College)H-Index: 24
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: Clinical trials with autologous adipose-derived stem cell (AdSC) therapy for ischemic heart diseases (IHDs) are ongoing. However, little is known about combinational therapeutic effect of AdSCs and statin poly(lactic-co-glycolic) acid (PLGA) nanoparticles on the ischemic myocardium. We investigated the hypothesis that statins, which have pleiotropic effects, augment the therapeutic potential of AdSCs and that AdSCs also act as drug delivery tools. Simvastatin-conjugated nanoparticles (SimNPs) ...
5 CitationsSource
#1Ryoto Hourai (Osaka Medical College)H-Index: 3
#2Hideki Ozawa (Osaka Medical College)H-Index: 7
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
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: The prevalence and extent of immunoglobulin G4 (IgG4)-positive cell infiltration were investigated in 282 surgical samples of aortic wall and aortic valve. Tissue infiltration of IgG4-positive cells was observed in 24 (17.3%) of 139 aortic valve samples and 46 (32%) of 143 aortic wall samples, and the condition of IgG4-positive cell infiltration > 30/hpf together with IgG4/CD138 ratio > 40% was observed in 2 (1.4%) of aortic valve samples and 14 (9.8%) of aortic wall samples. Among 275 patient...
3 CitationsSource
#1Yohei Yamauchi (Osaka Medical College)H-Index: 6
#2Yumiko Kanzaki (Osaka Medical College)H-Index: 12
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
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Background Attenuation correction using segmentation of scatter and photo-peak window data (SSPAC) enables an evaluation of the attenuation map in a patient-specific manner without additional radiation exposure. We compared the accuracy of SSPAC and non-corrected myocardial perfusion scintigraphy methods for diagnosing the number of stenosed coronary artery vessels.
#1Ichiro Mizushima (Kanazawa University)H-Index: 12
#2Satomi Kasashima (Kanazawa University)H-Index: 21
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
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AbstractPeriaortitis and periarteritis are one of the clinical features of IgG4-related disease. Such vascular manifestations are reported to be present in 10–30% of overall IgG4-related disease, a...
12 CitationsSource
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