Carlos Fernandez-del Castillo
Harvard University
CancerInternal medicineRadiologySurgeryPathologyOncologyRetrospective cohort studyPancreatitisIntraductal papillary mucinous neoplasmPancreatic diseaseCarcinomaPancreatectomyPancreasPancreaticoduodenectomyPancreatic cancerAdenocarcinomaGeneral surgeryMedicineBiologyGastroenterology
Publications 546
#1Scott Ferguson (Harvard University)H-Index: 1
#2Katherine S. Yang (Harvard University)H-Index: 20
Last. Ralph Weissleder (Harvard University)H-Index: 205
view all 7 authors...
Tumor cell derived extracellular vesicles (EV) are being explored as circulating biomarkers for cancer detection. Up to now however, clinical results have been mixed for a number of reasons including the predominant use of bulk measurements, the inability to differentiate tumor from host cell derived vesicles, the general absence of uniquely identifying biomarkers and the unknown frequency of stochastically distributed biomarkers into single circulating vesicles. We hypothesized that a single EV...
#1Lisa Suzanne Brubaker (BCM: Baylor College of Medicine)H-Index: 2
#2Fabio Casciani (University of Verona)H-Index: 2
Last. Chad G. Ball (U of C: University of Calgary)H-Index: 47
view all 26 authors...
Abstract null null Background null Intraperitoneal drain placement decreases morbidity and mortality in patients who develop a clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreaticoduodenectomy (PD). It is unknown whether multiple drains mitigate CR-POPF better than a single drain. We hypothesize that multiple drains decrease the complication burden more than a single drain in cases at greater risk for CR-POPF. null null null Methods null The Fistula Risk Score (FRS...
#1Jorge Roldan (Harvard University)
#2Jon M. HarrisonH-Index: 2
Last. Martha B. PitmanH-Index: 53
view all 15 authors...
Objective null To describe our institutional experience with resected cystic tumors of the pancreas with emphasis on changes in clinical presentation and accuracy of preoperative diagnosis. null Summary background data null Incidental-discovery of pancreatic cystic lesions has increased and has led to a rise in pancreatic resections. It is important to analyze surgical outcomes from these procedures, and the prevalence of malignancy, pre-malignancy and resections for purely benign lesions, some ...
#6Jason ReevesH-Index: 8
#1Pascal Probst (Heidelberg University)H-Index: 22
#2Felix J Hüttner (Heidelberg University)H-Index: 16
Last. Marco Del Chiaro (Anschutz Medical Campus)H-Index: 31
view all 45 authors...
BACKGROUND Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery. METHODS PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all...
1 CitationsSource
#1Roi Anteby (Harvard University)H-Index: 3
#2Keith D. Lillemoe (Harvard University)H-Index: 124
Last. Motaz Qadan (Harvard University)H-Index: 21
view all 5 authors...
Abstract Background Pancreatic operations are technically complex with a significant risk of morbidity and mortality. Analysis of litigation following surgery can disclose avoidable errors. Methods Two legal databases, Westlaw and Lexis Nexis, were queried for jury verdicts, settlements and appeal cases in the United States related to pancreatic surgery and malpractice between 1980 and 2020. Results Thirty-four cases were analyzed. Pancreaticoduodenectomy (n = 22, 65%) was the most common proced...
#1Vishwajith Sridharan (Harvard University)H-Index: 6
#2Mari Mino-Kenudson (Harvard University)H-Index: 93
Last. Yasmin G. Hernandez-Barco (Harvard University)H-Index: 3
view all 21 authors...
Abstract Background Acinar cell carcinoma (ACC) is a very rare tumor of the exocrine pancreas, representing less than 1% of all pancreatic malignancies. The majority of data regarding ACC are limited to small case series. Methods This is a retrospective study conducted at a large healthcare system from 1996 to 2019. Patients with pathologically confirmed ACC were included, and demographic data, tumor characteristics, and treatment outcomes were abstracted by chart review. Survival curves were ob...
1 CitationsSource
#1Roi AntebyH-Index: 3
Last. Motaz QadanH-Index: 21
view all 8 authors...
#1Jon M. HarrisonH-Index: 2
#2Jonathan ChangH-Index: 5
Last. Andrew S. LissH-Index: 20
view all 12 authors...