Subhash C. Chauhan
University of Texas at Austin
CancerInternal medicinePathologyChemistryApoptosisImmunologyOrmeloxifeneCervical cancerCurcuminMetastasisDrug deliveryProstate cancerPancreatic cancerCell cycleCancer researchCell growthMedicineBiologyCancer cellPharmacology
Publications 252
#1Andrew E. Massey (NIH: National Institutes of Health)
#1Andrew E. Massey (NIH: National Institutes of Health)H-Index: 5
Last. Bilal Bin Hafeez (University of Texas at Austin)H-Index: 29
view all 10 authors...
Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implication...
#1Deepak S. Chauhan (University of Texas at Austin)
#1Deepak S. ChauhanH-Index: 10
Last. Murali M. YallapuH-Index: 34
view all 9 authors...
Novel strategies modulating the immune system yielded enhanced anticancer responses and improved cancer survival. Nevertheless, the success rate of immunotherapy in cancer treatment has been below expectation(s) due to unpredictable efficacy and off-target effects from systemic dosing of immunotherapeutic. As a result, there is an unmet clinical need for improving conventional immunotherapy. Nanotechnology offers several new strategies, multimodality, and multiplex biological targeting advantage...
#1Pallabita Chowdhury (UTHSC: University of Tennessee Health Science Center)H-Index: 12
#2Upasana Ghosh (RU: Rutgers University)
Last. Murali M. Yallapu (University of Texas at Austin)H-Index: 34
view all 6 authors...
The management of aggressive breast cancer, particularly, triple negative breast cancer (TNBC) remains a formidable challenge, despite treatment advancement. Although newer therapies such as atezolizumab, olaparib, and sacituzumab can tackle the breast cancer prognosis and/or progression, but achieved limited survival benefit(s). The current research efforts are aimed to develop and implement strategies for improved bioavailability, targetability, reduce systemic toxicity, and enhance therapeuti...
#1Ananya Dutta (U of M: University of Memphis)H-Index: 1
#2Bonny Banerjee (U of M: University of Memphis)H-Index: 11
Last. Subhash C. Chauhan (University of Texas at Austin)H-Index: 5
view all 4 authors...
Background: Pancreatic cancer (PC) is a disease with poor prognosis and survival rate. There is a pertinent need to identify the risk factors of this disease. The purpose of this study is to use machine learning methods to identify a subset of factors (a.k.a. features) from the PLCO dataset as predictors of PC. The Prostate, Lung, Colorectal and Ovarian (PLCO) cancer dataset is collected by the National Cancer Institute from 155,000 participants (49.5% male). Each participant responded to three ...
#1Sudhir Kotnala (The University of Texas Rio Grande Valley)H-Index: 1
#2Anupam Dhasmana (The University of Texas Rio Grande Valley)H-Index: 1
Last. Meena Jaggi (University of Texas at Austin)H-Index: 1
view all 6 authors...
Cystic fibrosis (CF) is an autosomal recessive disease which involves the mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CF involves the inflammatory processes and is considered as a multisystem disorder that is not confined to lungs, but it also affects other vital organs that leads to numerous co-morbidities. The respiratory disorder in the CF results in mortality and morbidity which is characterized by series of serious events involving mucus hypersecretion,...
#1Benilde Adriano (University of Texas at Austin)H-Index: 1
#2Nycol M. Cotto (University of Texas at Austin)H-Index: 1
Last. Murali M. Yallapu (University of Texas at Austin)H-Index: 34
view all 6 authors...
Abstract Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are smaller intracellular membrane nanoparticle vesicles. Exosomes have proven to be excellent nanocarriers for carrying lipids, proteins, mRNAs, non-coding RNAs, and DNAs, and disseminating long-distance intercellular communications in various biological processes. Among various cell-line or biological fluid derived exosomes, milk exosomes are abundant in nature and exhibit many nanocarrier characte...
7 CitationsSource
#1Neeraj Chauhan (University of Texas at Austin)H-Index: 1
#1Neeraj Chauhan (University of Texas at Austin)H-Index: 24
Last. Murali M. Yallapu (University of Texas at Austin)H-Index: 34
view all 4 authors...
The novel coronavirus (CoV) disease 2019 (COVID-19) is a viral infection that causes severe acute respiratory syndrome (SARS). It is believed that early reports of COVID-19 cases were noticed in De...
10 CitationsSource
#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. João Conde (NOVA: Universidade Nova de Lisboa)H-Index: 33
view all 13 authors...
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019, which has spread rapidly and become a global pandemic. The number of cases of COVID-19 and its associated mortality have raised serious concerns worldwide. Early diagnosis of viral infection undoubtedly allows rapid intervention, disease management, and substantial control of the rapid spread of the disease. Currently, the standard approach for COVID-19 diagnosis globally is the RT-qPCR test; however, the limit...
12 CitationsSource
#1Subhash C. ChauhanH-Index: 49
Last. Amar Kant GautamH-Index: 6
view all 6 authors...
#1Anshuman PandeyH-Index: 2
#1Ajoy Kumar PandeyH-Index: 8
Last. Suneed KumarH-Index: 4
view all 6 authors...