Kenta Yamamura
Kanazawa University
Fusion geneAnaplastic lymphoma kinaseInternal medicineRadiologyImmunoglobulin EPathologyOncologyAntibodyEndogenyRetrospective cohort studyStage (cooking)CytologyProspective cohort studyAdverse effectImmunologyImmunohistochemistryTransformation (genetics)FEV1/FVC ratioBiopsyAsthmaFine-needle aspirationLung cancerEveningBronchial thermoplastyChemotherapyPrednisoloneCOPDForcepsInhalationUsual interstitial pneumoniaInterstitial lung diseaseCarcinomaChronic coughLungEsophagusReceptor antagonistIdiopathic pulmonary fibrosisRespimatDiscontinuationGuinea pigBronchoscopyEpidermal growth factor receptorMEDLINEPneumonitisRespiratory tractNivolumabContext (language use)PembrolizumabSingle CenterNintedanibBody mass indexMethylprednisoloneEndoscopic ultrasoundPsoriasisProstaglandinBronchoconstrictionImmune checkpointExhaled nitric oxideAdenocarcinomaMethacholineCarboplatinMaintenance doseTransbronchial lung biopsyPeak flow meterHilar lymph nodesBronchial provocation testsEGFR Tyrosine Kinase InhibitorsMethacholine chlorideCough variant asthmaHot biopsyRespiratory impedanceNon small cellSeverity of illnessSignificant differenceHistological examinationHealthy subjectsTreatment outcomeEbus tbnaAsthma copd overlapAnesthesiaRespiratory systemVital capacityText miningMedicineFeature (computer vision)Pulmonary function testingPharmacology
15Publications
3H-index
92Citations
Publications 15
Newest
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#1Hideharu KimuraH-Index: 21
#2Takashi SoneH-Index: 12
Last. Kazuo KasaharaH-Index: 28
view all 9 authors...
Awareness of the immune-related adverse event of programmed cell death protein-1 (PD-1) inhibitor-induced pneumonitis is important. Herein, we report the clinical course of 3 patients suspected to have PD-1 inhibitor-induced pneumonitis after cessation of PD-1 inhibitor treatment. In case 1, a 62-year-old man was diagnosed with stage IVA adenocarcinoma. Nivolumab monotherapy was prescribed as second-line therapy and later discontinued due to financial reasons. Seven months after the final admini...
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#1Kenta Yamamura (Kanazawa University)H-Index: 3
#2Johsuke Hara (Kanazawa University)H-Index: 12
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 12 authors...
Abstract Background Cough variant asthma (CVA) is recognized as a precursor of bronchial asthma (BA). However, the cough response to bronchoconstriction differs between these similar diseases. Repeated bronchoconstriction and the resulting imbalance of endogenous lipid mediators may impact the cough response. Methods We investigated the influence of repeated bronchoconstriction on the cough response to bronchoconstriction using naive guinea pigs. Bronchoconstriction was induced for 3 consecutive...
1 CitationsSource
#1Tamami SakaiH-Index: 3
#5Akihito Okazaki (Kanazawa University)H-Index: 5
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 7 authors...
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) increases the risk of lung cancer. The relationships between COPD and Asthma COPD Overlap (ACO), and between the histopathological types of lung cancer and driver mutations remain unclear and need further study. The aim of this retrospective study was to examine the relationships between the histopathological type, frequency of epidermal growth factor receptor (EGFR) driver mutations, and anaplastic lymphoma receptor tyrosine kinase (ALK) ...
1 CitationsSource
#1Akari Murata (Kanazawa University)H-Index: 2
#2Satoshi Watanabe (Kanazawa University)H-Index: 11
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 9 authors...
2 CitationsSource
#1Kenta Yamamura (Kanazawa University)H-Index: 3
#2Johsuke Hara (Kanazawa University)H-Index: 12
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 7 authors...
BACKGROUND: Bronchial thermoplasty (BT) is a novel bronchoscopic therapy for severe uncontrolled asthma unresponsive to standard pharmacological treatments, including inhaled corticosteroids and long-acting beta-2 agonists. Although several studies have shown that BT improves asthma control, the optimal predictors of BT response remain unknown. PATIENTS AND METHODS: We reviewed 10 consecutive asthma patients treated with BT at Kanazawa University Hospital between January 2016 and March 2018 and ...
3 CitationsSource
#1Johsuke Hara (Kanazawa University)H-Index: 12
#2Kazuo Kasahara (Kanazawa University)H-Index: 28
Last. Hideharu Kimura (Kanazawa University)H-Index: 21
view all 14 authors...
Objective In Japan, most asthma deaths occur among the elderly. We should improve the control of asthma in elderly patients to reduce the number of deaths due to asthma. This retrospective study aimed to evaluate the efficacy of tiotropium RespimatⓇ (Tio-Res) in symptomatic, never-smoking, elderly asthmatics with irreversible airflow limitation despite the use of high-dose inhaled corticosteroids (ICS) plus long-acting β2-adrenoceptor agonists (LABA). Methods The Asthma Control Test™ (ACT), pulm...
1 CitationsSource
#1Tomoyuki ArayaH-Index: 7
#2Toshiyuki KitaH-Index: 15
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 11 authors...
Background. Standard chemotherapy for advanced non-small-cell lung cancer (NSCLC) with preexisting interstitial lung disease (ILD) has not yet been established. Although a combination of carboplatin and paclitaxel is most frequently used for patients with advanced NSCLC and ILD, the safety and efficacy of carboplatin plus nanoparticle albumin-bound paclitaxel (nab-paclitaxel) are yet to be elucidated. Objectives. This study aimed to evaluate the safety and efficacy of carboplatin plus nab-paclit...
3 CitationsSource
#1Kenta Yamamura (Kanazawa University)H-Index: 3
#2Johsuke Hara (Kanazawa University)H-Index: 12
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 16 authors...
: Background Asthma-COPD overlap (ACO) is a disease that shares clinical features of both asthma and COPD. The purpose of this study is to investigate the prevalence and clinical features of ACO. Methods We retrospectively reviewed data for 170 patients with persistent airflow limitation and diagnosed them according to "The Japanese Respiratory Society Guidelines for the Management of ACO 2018". Results Of the 170 patients, 111 were diagnosed as follows : COPD (74 patients, 66.6%), ACO (34 patie...
7 CitationsSource
#1Tamami Sakai (Kanazawa University)H-Index: 3
#2Johsuke Hara (Kanazawa University)H-Index: 12
Last. Shinji Nakao (Kanazawa University)H-Index: 59
view all 12 authors...
AbstractPurpose/Aim of the study: Methacholine chloride (MCh) inhalation causes bronchoconstriction and cough. Following MCh-induced bronchoconstriction, metabolic products of prostaglandin I2 (PGI...
1 CitationsSource