Giacomo Carlo Sturniolo
University of Messina
Internal medicineEndocrinologySurgeryPathologyChemistryImmunologyMetallothioneinColitisInflammationInflammatory bowel diseaseDiseaseCrohn's diseaseLiver transplantationUlcerative colitisIn patientIntestinal mucosaZincMedicineBiologyGastroenterology
Publications 295
#1Flavia Merigo (University of Verona)H-Index: 24
#2Alessandro Brandolese (University of Verona)H-Index: 3
Last. Andrea Sbarbati (University of Verona)H-Index: 59
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The expression of leptin and leptin receptor (Ob-R) has been partially elucidated in colon of patients with inflammatory bowel diseases (IBDs), even though leptin is involved in angiogenesis and inflammation. We previously reported overexpression of GLUT5 fructose transporter, in aberrant clusters of lymphatic vessels in lamina propria of IBD and controls. Here, we examine leptin and Ob-R expression in the same biopsies. Specimens were obtained from patients with ulcerative colitis (UC), Crohn's...
#1Simona De AngelisH-Index: 5
#2Marcello Bagnasco (UniGe: University of Genoa)H-Index: 37
Last. Antonella OlivieriH-Index: 17
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Background: The frequency of overweight (OW) and obese (OB) children has increased worldwide, particularly in economically developed countries. No studies have been conducted to verify whether the ...
1 CitationsSource
#1Antonino CarusoH-Index: 4
#2Imerio Angriman (UNIPD: University of Padua)H-Index: 25
Last. Carmelo LacognataH-Index: 11
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Background Intestinal fibrosis is a key feature of Crohn’s Disease lesions, and mucosal biopsies do not exactly represent transmural damage. Magnetic resonance enterography (MRE) allows for a panoramic study of the bowel loops. Diffusion-weighted imaging (DWI) through the restriction of the apparent diffusion coefficient (ADC) allows for an accurate evaluation of disease activity in Crohn’s Disease patients avoiding contrast agents. The aim of this study was to investigate whether DWI sequences ...
1 CitationsSource
#1Brigida Barberio (UNIPD: University of Padua)H-Index: 7
#2Sonia Facchin (UNIPD: University of Padua)H-Index: 11
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
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Background:Faecal microbiota transplantation (FMT) is a reasonable therapeutic option for the treatment of Clostridioides difficile infection (CDI) recurrent and refractory (RCDI) to therapy, but l...
1 CitationsSource
#1Sonia FacchinH-Index: 11
#2Nicola Vitulo (University of Verona)H-Index: 27
Last. Edoardo SavarinoH-Index: 60
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BACKGROUND Butyrate has shown anti-inflammatory and regenerative properties, providing symptomatic relief when orally supplemented in patients suffering from various colonic diseases. We investigated the effect of a colonic-delivery formulation of butyrate on the fecal microbiota of patients with inflammatory bowel diseases (IBDs). METHODS In this double-blind, placebo-controlled, pilot study, 49 IBD patients (n = 19 Crohn's disease, CD and n = 30 ulcerative colitis, UC) were randomized to oral ...
4 CitationsSource
#1Brigida Barberio (UNIPD: University of Padua)H-Index: 7
#2Giacomo Carlo Sturniolo (UNIPD: University of Padua)H-Index: 48
Last. Edoardo Savarino (UNIPD: University of Padua)H-Index: 60
view all 8 authors...
#1Gionata FiorinoH-Index: 51
Last. Silvio DaneseH-Index: 100
view all 7 authors...
IBD98-M is a delayed-release formulation of mesalamine (mesalazine) and SH with a potential therapeutic role in ulcerative colitis (UC). A total of 51 patients with a modified Ulcerative Colitis Disease Activity Index (UCDAI) score of ≥4 and ≤10, and a modified UCDAI endoscopy subscore ≥1 were randomized for 6 weeks of double-blind treatment with IBD98 0.8 g/day or IBD 1.2 g/day or placebo. The efficacy and safety of IBD98-M in mild to moderate active UC were primarily evaluated. At week 6, 1 (5...
2 CitationsSource
#1Mariacarla Moleti (UNIME: University of Messina)H-Index: 16
#2Maria Di Mauro (UNIME: University of Messina)H-Index: 3
Last. Francesco Vermiglio (UNIME: University of Messina)H-Index: 22
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Abstract Hyperthyroidism during pregnancy is uncommon. Nonetheless, prompt identification and adequate management of hyperthyroidism in a pregnant woman is essential, because uncontrolled thyrotoxicosis significantly increases the risk of maternal and fetal complications. Also, fetal prognosis may be affected by the transplacental passage of maternal thyroid stimulating antibodies or thyrostatic agents, both of which may disrupt fetal thyroid function. Birth defects have been reported in associa...
11 CitationsSource
Background and aims Sexual functions are sometimes adversely affected by the therapeutic drugs delivered for treating IBD. Much attention has been focused on pregnancy/sexual issues in women. Relatively less attention has been poured in to address this issue in men. This systematic review assesses the drugs having potential detrimental effects on fertility in men. Methods Three databases were searched by two researchers independently for potentially relevant publications between 1964 to 2015 and...
3 CitationsSource
#1Mariacarla MoletiH-Index: 16
Last. Francesco VermiglioH-Index: 22
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Thyroid autoimmunity affects 5–20% of the female population of childbearing age. Even in the absence of overt maternal thyroid dysfunction, thyroid autoimmunity has been reported to be associated with an increased risk of adverse pregnancy outcomes and impaired fetal neurodevelopment. Present evidence indicates that thyroid autoimmunity poses a risk for miscarriage and preterm delivery. By contrast, with regard to infertility most studies failed to find significantly different likelihood of preg...
1 CitationsSource