Kentaro Fujii
Okayama University
Internal medicineRadiologyNeurosurgerySurgeryPathologyCellGene expressionIntegrinGlioblastomaVascular endothelial growth factorBevacizumabGliomaCilengitideAngiogenesisAnnexin A2Cancer researchText miningMedicineBiologyPharmacology
Publications 37
#1Yuki Otsuka (Okayama University)H-Index: 1
#2Hideharu Hagiya (Okayama University)H-Index: 13
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 6 authors...
#1Yusuke Tomita (Okayama University)H-Index: 6
#2Yosuke Shimazu (Okayama University)H-Index: 6
Last. Isao Date (Okayama University)H-Index: 58
view all 12 authors...
Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection ...
#1Yasuhiko HattoriH-Index: 5
Last. Yosuke ShimazuH-Index: 6
view all 13 authors...
#1Atsuhito Uneda (Okayama University)H-Index: 8
#2Kazuhiko Kurozumi (Okayama University)H-Index: 23
Last. Isao Date (Okayama University)H-Index: 58
view all 15 authors...
Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular heterogeneity, namely tumor cells, including GBM stem-like cells (GSCs) and differentiated GBM cells (DGCs), and non-tumor cells such as endothelial cells, vascular pericytes, macrophages, and other types of immune cells. GSCs are essential to drive tumor progression, whereas the biological roles of DGCs are largely unknown. In this study, we focused on the roles of DGCs in the tumor microenvironment....
2 CitationsSource
#1Satoru Yabuno (Okayama University)H-Index: 2
#2Satoshi Kawauchi (Okayama University)H-Index: 3
Last. Shohei KohnoH-Index: 15
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A 23-year-old woman was referred to our hospital with progressive headache and back pain. Cerebrospinal fluid(CSF)analysis revealed hypoglycorrhachia and pleocytosis. However, imaging studies did not reveal evidence of subarachnoid hemorrhage(SAH), and she was diagnosed with bacterial meningitis. CSF analysis repeated after antibiotic treatment continued to show evidence of blood. Spinal SAH was suspected, and MRI revealed a spinal arteriovenous malformation(AVM). Spinal digital subtraction angi...
#1Yusuke TomitaH-Index: 6
#2Kazuhiko KurozumiH-Index: 23
Last. Isao DateH-Index: 58
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Breast cancer is the most common malignancy among women worldwide, and the main cause of death in patients with breast cancer is metastasis. Metastasis to the central nervous system occurs in 10% to 16% of patients with metastatic breast cancer, and this rate has increased because of recent advancements in systemic chemotherapy. Because of the various treatments available for brain metastasis, accurate diagnosis and evaluation for treatment are important. Magnetic resonance imaging (MRI) is one ...
#1Yuji Matsumoto (Okayama University)H-Index: 6
#2Tomotsugu Ichikawa (Okayama University)H-Index: 22
Last. Isao Date (Okayama University)H-Index: 58
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Glioblastoma (GBM) is characterized by extensive tumor cell invasion, angiogenesis, and proliferation. We previously established subclones of GBM cells with distinct invasive phenotypes and identified annexin A2 (ANXA2) as an activator of angiogenesis and perivascular invasion. Here, we further explored the role of ANXA2 in regulating phenotypic transition in GBM. We identified oncostatin M receptor (OSMR) as a key ANXA2 target gene in GBM utilizing microarray analysis and hierarchical clusterin...
4 CitationsSource
#1Namiko Matsumoto (Okayama University)H-Index: 4
#2Kota Sato (Okayama University)H-Index: 17
Last. Koji Abe (Okayama University)H-Index: 82
view all 12 authors...
1 CitationsSource