Roberto Bertini
Vita-Salute San Raffaele University
CancerInternal medicineRadiologyUrologySurgeryOncologyRenal functionRenal cell carcinomaCarcinomaKidney diseaseProstatectomyProstate cancerNephrectomyLymph nodeKidney cancerNephron sparing surgeryIn patientProportional hazards modelGeneral surgeryMedicine
Publications 338
#1Alberto MartiniH-Index: 34
#2Alessandro LarcherH-Index: 31
Last. Umberto CapitanioH-Index: 63
view all 14 authors...
Abstract Surgical treatment of small renal masses (RMs) is still characterized by a non-negligible rate of benign histology, ultimately resulting in overtreatment. Since the risk of kidney cancer increases with age and the risk of malignancy usually increases with tumor size, we created a model based on patient age, RM size, and their interaction for predicting malignant histology. As male sex is associated with a higher risk of renal malignancy, we also stratified our analyses by sex. We used d...
#1Giuseppe RosielloH-Index: 8
#2Giuseppe FallaraH-Index: 5
Last. Isaline RoweH-Index: 12
view all 22 authors...
#1Luigi Nocera (UdeM: Université de Montréal)H-Index: 8
#2Lara Franziska Stolzenbach (UdeM: Université de Montréal)H-Index: 5
Last. Alberto BrigantiH-Index: 99
view all 17 authors...
We hypothesized that pT3a stage at nephrectomy can be accurately predicted in cT1N0M0 clear cell-renal cell carcinoma (cc-RCC) patients. Of 236 patients, treated with either partial or radical nephrectomy (2005-2019), 25 (10.6%) harbored pT3a stage. Multivariable logistic regression models predicting pT3a were fitted using age, tumor size, tumor location and exophytic rate. The new model was 81% accurate. In calibration plots, minimal departures from ideal prediction were recorded. In decision c...
#1Carlo Andrea Bravi (UniSR: Vita-Salute San Raffaele University)H-Index: 10
#2Alessandro Larcher (UniSR: Vita-Salute San Raffaele University)H-Index: 31
Last. Andrea Minervini (UniFI: University of Florence)H-Index: 41
view all 30 authors...
Abstract Background Partial nephrectomy (PN) has a non-negligible perioperative morbidity. Comparative evidence of the available surgical techniques is limited. Objective To compare the perioperative outcomes of open, laparoscopic, and robotic PN. Methods Data of 2331 patients treated with PN for cT1 renal tumors were extracted from the RECORd2 database, a prospective multicenter project. Multivariable regression models assessed the relationship between surgical technique and surgical margins, w...
#1Umberto CapitanioH-Index: 63
#2Gino PepeH-Index: 3
Last. Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 140
view all 18 authors...
BACKGROUND The accurate detection of nodal invasion is an unmet need in the clinical staging of renal cancer. Positron emission tomography (PET) with 18F-fluoroazomycin arabinoside (18F-FAZA), a hypoxia specific tracer, is a non-invasive imaging method that detects tumour hypoxia. The aim of this work was to evaluate the role of 18F-FAZA PET/CT in the identification of lymph node metastases in renal cancer. METHODS A proof-of-concept phase 2 study including 20 kidney cancer patients ( ClinicalTr...
#1Umberto Capitanio (UniSR: Vita-Salute San Raffaele University)H-Index: 63
#2Alessandro Larcher (UniSR: Vita-Salute San Raffaele University)H-Index: 31
Last. Francesco Montorsi (UniSR: Vita-Salute San Raffaele University)H-Index: 140
view all 15 authors...
PURPOSE The role of non-tumour renal biopsy in predicting renal function after surgery for renal cell carcinoma (RCC) is poorly investigated. The aim of the study was to assess the impact of renal parenchymal histology on renal function after radical nephrectomy in a cohort of patients with RCC. METHODS This cohort study included 171 patients with RCC submitted to radical nephrectomy between 2006 and 2018. Two biopsy samples from normal parenchyma were collected at nephrectomy and renal parenchy...
#1Alessandro Nini (Saarland University)H-Index: 14
#2Fabio Muttin (UniSR: Vita-Salute San Raffaele University)H-Index: 6
Last. Roberto Bertini (UniSR: Vita-Salute San Raffaele University)H-Index: 32
view all 26 authors...
Background Scarce data are available regarding the technique and outcomes for patients with RCC and Mayo III caval thrombi. To report surgical and oncological outcomes of RCC patients with Mayo III thrombi treated with radical nephrectomy and thrombectomy after liver mobilization (LM) and Pringle Manoeuvre (PM). Methods Retrospective analysis of surgical technique, outcomes and cancer control in 19 patients undergoing LM and PM in a single tertiary care institution. Results Overall, 78% of the p...
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