Hidemi Goto
Nagoya University
CancerInternal medicineRadiologyEndocrinologySurgeryPathologyOncologyVirologyChemistryImmunologyBiopsyHelicobacter pyloriCapsule endoscopyEndoscopyStomachEndoscopic ultrasonographyIn patientMedicineBiologyGastroenterology
Publications 963
#1Masaaki MinamiH-Index: 9
Last. Michio OhtaH-Index: 4
view all 6 authors...
Na+/H+ antiporter plays an important role in maintaining cellular homeostasis by regulating osmotic pressure and intracellular pH. It plays an important role in maintaining cellular homeostasis. In Helicobacter pylori, whole genome sequencing has revealed the presence of two types of Na+/H+ antiporter. A gene (nhaA) homologous to the Na+/H+ antiporter of Escherichia coli has been investigated and its function has been analyzed. However, another gene homologous to the Na+/H+ antiporter of Enteroc...
#1Masaaki MinamiH-Index: 9
#2Takafumi AndoH-Index: 9
Last. Michio OhtaH-Index: 4
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Mupirocin (MUP) is an effective antibiotic against MRSA. Its bactericidal effect is stable under acid condition. By validating its antibacterial effect of Helicobacter pylori, we try to clarify MUP effect on H. pylori. The present study was conducted to investigate the effect of MUP on clarithromycin (CLR) / metronidazole (MNZ) -resistant and -susceptible strains of H. pylori, the time-kill effect of MUP, and the post antibiotic effect (PAE). We investigated the minimal inhibitory concentration ...
#1Masaaki MinamiH-Index: 9
Last. Michio OhtaH-Index: 4
view all 6 authors...
Helicobacter pylori (H. pylori) urease generates both ammonia (NH3) and carbon dioxide (CO2) from urea. NH3 helps H. pylori to survive in the stomach in part by neutralizing gastric acid. However, the relationship between CO2 and H. pylori is not completed cleared. We examined the effect of CO2 generated by urease on multiplication of H. pylori by using isogenic ureB mutant and ureB complemented strain from H. pylori strain JP26. Wild-type strain survived in the medium supplement with 1mM urea i...
#1Ran Zhao (SJTU: Shanghai Jiao Tong University)
#2Masanao Nakamura (Nagoya University)H-Index: 25
Last. Zhi-Zheng Ge (SJTU: Shanghai Jiao Tong University)H-Index: 23
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Background and aim Video capsule endoscopy (VCE) is a first-line procedure for the diagnosis of obscure gastrointestinal bleeding (OGIB). The opinions on the timing for such diagnostic evaluation remain unclear. We aimed to explore the role of early VCE in OGIB patients. Methods We used 997 total patients in this study that underwent VCE at Renji Hospital and Nagoya University from May 15, 2002, through December 28, 2016 were included in this study. We matched patients that underwent early VCE w...
1 CitationsSource
The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in 2019; thereafter, the COVID-19 outbreak became a health emergency of international concern. The impact of COVID-19 on liver-transplant recipients is unclear. Thus, it is currently unknown whether liver-transplant recipients are at a higher risk of developing complications related to COVID-19. Here, we report the case of liver-transplant recipients who wer...
2 CitationsSource
#1Masanao Nakamura (Nagoya University)H-Index: 25
#2Kenji Watanabe (Fujita Health University)H-Index: 27
Last. Toshiyuki Matsui (Fukuoka University)H-Index: 57
view all 14 authors...
STUDY AIMS: The PillCam(TM) patency capsule (PPC) is an Agile tag-less patency capsule used to evaluate gastrointestinal (GI) patency. We determined the appropriate use of PPC to preclude subsequent small bowel capsule endoscopy (SBCE) retention. METHODS: This prospective multicenter study consecutively enrolled patients indicated for SBCE with suspected or established small bowel stenosis. Excretion of an intact PPC or its radiologic visualization in the large bowel was considered GI patency. P...
2 CitationsSource
#1Keiichi Sakamaki (Nagoya University)
#2Kohei Funasaka (Nagoya University)H-Index: 14
Last. Hidemi Goto (Nagoya University)H-Index: 72
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Although the majority of gastrointestinal stromal tumors (GISTs) possess KIT mutations that induce constitutive signal transduction, the clinical outcomes are variable. The ETS translocation variant 1 (ETV1) gene encodes a transcription factor that is reported to cooperate with KIT in GISTs. However, the clinical role of ETV1 is largely unknown. The aim of this study was to examine ETV1 expression and its associations with clinical features in GISTs. We conducted a cohort study involving 64 pati...
#1Toshihisa Fujiyoshi (Nagoya University)H-Index: 6
#2Masahiro TajikaH-Index: 33
Last. Yoshimitsu NiwaH-Index: 17
view all 13 authors...
#1Hiroto SuzukiH-Index: 2
#2Takeshi YamamuraH-Index: 12
Last. Hidemi GotoH-Index: 72
view all 9 authors...
Background: The Japan narrow-band imaging Expert Team (JNET) classification of colorectal polyps based on magnifying endoscopy is used in Japan, but not worldwide. The objective of this study was to clarify differences of diagnostic accuracy between JNET users in Japan and non-JNET users in other countries. Methods: A total of 185 colorectal tumors were assessed. Six endoscopists (3 each from Japan and Taiwan) participated in the study. The Japanese endoscopists normally used the JNET classifica...
6 CitationsSource
#1Chie Tanaka (Nagoya University)H-Index: 10
#2Mitsuro Kanda (Nagoya University)H-Index: 46
Last. Yasuhiro Kodera (Nagoya University)H-Index: 81
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INTRODUCTION: In laparoscopic gastrectomy, a method to locate the margin of an early-stage cancerous lesion that is invisible from the serosal surface and impalpable during laparoscopic procedures is needed to determine an appropriate transection line. We conducted a prospective study to develop a new marking method using preoperative submucosal injection of indocyanine green (ICG). METHODS: Patients undergoing laparoscopic gastrectomy for T1 gastric cancer were recruited. The first 11 patients ...
3 CitationsSource