Luis J. del Valle
Polytechnic University of Catalonia
BiophysicsConductive polymerElectrospinningNanoparticleCopolymerPEDOT:PSSNanotechnologyOrganic chemistryChemistryPolymer chemistryMaterials scienceCrystallizationBiocompatibilityPolythiopheneDrug deliveryChemical engineeringPolymerizationCrystallinityPolymerMedicineBiologyNanofiber
193Publications
27H-index
2,501Citations
Publications 186
Newest
#1Wilmer Silva-Caso (Museo Nacional Del Prado)H-Index: 2
#1Wilmer Silva-Caso (Museo Nacional Del Prado)H-Index: 9
Last. Juana del Valle-Mendoza (UPC: Universidad Peruana de Ciencias Aplicadas)H-Index: 10
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Abstract Introduction Oropouche fever is an under-reported and emerging infectious disease caused by Oropouche virus (OROV). Its incidence is under-estimated mainly due to clinical similarities with other endemic arboviral diseases and the lack of specific diagnostic tests. We report the first outbreak of Oropouche fever in a western region of the Peruvian Amazon in Huanuco, Peru. Methods A transversal study was carried out during an outbreak in the western Region of Huanuco, Peru between Januar...
6 CitationsSource
#1Manuel Rivas (UPC: Polytechnic University of Catalonia)H-Index: 7
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 27
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
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In this research we propose a nanoplatform for anticancer therapy that is based on the combination of three components: (1) an antibiotic to target selectively the mitochondria of cancer cells, inhibiting their functions; (2) mineral nanoparticles (NPs) able to encapsulate the antibiotic and to enter into the cells across the cell membrane; and (3) a biocoating to protect the antibiotic during and/or after its regulated release, increasing its therapeutic efficacy. Chloramphenicol (CAM), a proto...
8 CitationsSource
#1Manuel Rivas (UPC: Polytechnic University of Catalonia)H-Index: 7
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 27
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
view all 7 authors...
Permanently polarized hydroxyapatite (HAp) particles have been prepared by applying a constant DC of 500 V at 1000?°C for 1 h to the sintered mineral. This process causes important chemical changes, as the formation of OH- defects (vacancies), the disappearance of hydrogenophosphate ions at the mineral surface layer, and structural variations reflected by the increment of the crystallinity. As a consequence, the electrochemical properties and electrical conductivity of the polarized mineral incr...
6 CitationsSource
#1Maximilien Lopes-Rodrigues (UPC: Polytechnic University of Catalonia)H-Index: 3
#2Anna Puiggalí-Jou (UPC: Polytechnic University of Catalonia)H-Index: 7
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
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The thermomechanical response of Omp2a, a representative porin used for the fabrication of smart biomimetic nanomembranes, has been characterized using microcantilever technology and compared with standard proteins. For this purpose, thermally induced transitions involving the conversion of stable trimers to bigger aggregates, local reorganizations based on the strengthening or weakening of intermolecular interactions, and protein denaturation have been detected by the microcantilever resonance ...
5 CitationsSource
#1Ina Keridou (UPC: Polytechnic University of Catalonia)H-Index: 4
#2Lourdes Franco (UPC: Polytechnic University of Catalonia)H-Index: 25
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
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Electrospun scaffolds constituted by different mixtures of two biodegradable polyesters are prepared. Specifically, materials with well differentiated properties can be derived from the blending of hydrophilic polyglycolide (PGA) and hydrophobic poly(e-caprolactone) (PCL), which are also two of the most applied polymers for biomedical uses. Electrospinning conditions are selected in order to get homogeneous and continuous fibers with diameters in the nano/micrometric range. These conditions are ...
3 CitationsSource
#1Georgina Fabregat (UPC: Polytechnic University of Catalonia)H-Index: 14
#2Ludmila Hodasova (UPC: Polytechnic University of Catalonia)H-Index: 1
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
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3D-Poly(3,4-ethylenedioxythiophene) (PEDOT) electrodes are prepared using the multi-step template-assisted approach. Specifically, poly(lactic acid) nano- and microfibers collected on a previously polymerized PEDOT film are used as templates for PEDOT nano- and microtubes, respectively. Morphological analysis of the samples indicates that 3D-PEDOT electrodes obtained using a low density of templates, in which nano- and microtubes are clearly identified, exhibit higher porosity, and specific surf...
3 CitationsSource
#1Angélica DíazH-Index: 13
#2Luis J. del ValleH-Index: 27
Last. Jordi PuiggalíH-Index: 39
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The capacity to load bacteriophages into electrospun nanofibers of two representative biocompatible polymers has been evaluated, paying special attention to the possibility of preserving their antibacterial activity. Specifically, the work involves the following steps: (a) Evaluation of the effect of the applied electrical field on the phage activity; (b) evaluation of the activity when a lyophilization process could be avoided by using water soluble polymers (e.g., poly(ethylene glycol); (c) ev...
6 CitationsSource
#1Manuel Rivas (UPC: Polytechnic University of Catalonia)H-Index: 7
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 27
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
view all 5 authors...
The industrial process of nitrogen fixation is complex and results in a huge economic and environmental impact. It requires a catalyst and high temperature and pressure to induce the rupture of the strong N–N bond and subsequent hydrogenation. On the other hand, carbon dioxide removal from the atmosphere has become a priority objective due to the high amount of global carbon dioxide emissions (i.e. 36 200 million tons in 2015). In this work, we fix nitrogen from N2 and carbon from CO2 and CH4 to...
11 CitationsSource
#1Yolanda Márquez (UPC: Polytechnic University of Catalonia)H-Index: 6
#2Lourdes Franco (UPC: Polytechnic University of Catalonia)H-Index: 25
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
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Source
#1Pau TuronH-Index: 11
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 27
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
view all 4 authors...
Hydroxyapatite (HAp) is a bioceramic material that is the main inorganic component of hard and connective tissues (e.g., bones and teeth). Therefore efforts to develop novel biomaterials as bone substitute are currently based on HAp composites. A good interaction and adhesion between HAp and the selected polymeric matrix is required to achieve good mechanical properties. The affinity between these two phases can be improved by chemical reaction of coupling agents with the hydroxyl groups on the ...
3 CitationsSource