Luis J. del Valle
Polytechnic University of Catalonia
Conductive polymerElectrospinningNanoparticleCopolymerPEDOT:PSSNanotechnologyChemistryPolymer chemistryMaterials scienceCrystallizationBiocompatibilityPolythiopheneDrug deliveryChemical engineeringPolymerizationCrystallinityPolymerMedicineBiologyNanofiber
192Publications
26H-index
2,456Citations
Publications 186
Newest
#1Juana del Valle-Mendoza (UPC: Universidad Peruana de Ciencias Aplicadas)H-Index: 9
#2Carlos Palomares-Reyes (UPC: Universidad Peruana de Ciencias Aplicadas)H-Index: 5
Last. Wilmer Silva-Caso (UPC: Universidad Peruana de Ciencias Aplicadas)H-Index: 7
view all 12 authors...
OBJECTIVE This study was carried out to determine the prevalence of leptospirosis among febrile patients with a suspicious clinical diagnosis of dengue fever in northern Peru. RESULTS A total of 276 serum samples from patients with acute febrile illness (AFI) and suspected diagnosis for dengue virus (DENV) were analyzed. We identified an etiological agent in 121 (47.5%) patients, DENV was detected in 30.4% of the cases, leptospirosis in 11.2% and co-infection by both pathogens was observed in 5....
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#1Juana del Valle-Mendoza (UPC: Universidad Peruana de Ciencias Aplicadas)H-Index: 9
Last. Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 26
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OBJECTIVE To determine the general and genotype-specific prevalence of HPV and to identify potential risk factors for the infection in a population-based screening of Peruvian women. RESULTS A total of 524 samples were analyzed by PCR and a total of 100 HPV positive samples were found, of which 89 were high-risk, 19 were probably oncogenic, 9 were low-risk and 27 other HPV types. The 26-35 and 36-45 age groups showed the highest proportion of HPV positive samples with a total of 37% (37/100) and...
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#1Brenda G. Molina (UPC: Polytechnic University of Catalonia)H-Index: 4
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 26
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
view all 8 authors...
Rapid detection of bacterial presence on implantable medical devices is essential to prevent biofilm formation, which consists of densely packed bacteria colonies able to withstand antibiotic-mediated killing. In this work, a smart approach is presented to integrate electrochemical sensors for detecting bacterial infections in biomedical implants made of isotactic polypropylene (i-PP) using chemical assembly. The electrochemical detection is based on the capacity of conducting polymers (CPs) to ...
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#1Hamidreza Enshaei (UPC: Polytechnic University of Catalonia)H-Index: 2
#2Anna Puiggalí-Jou (UPC: Polytechnic University of Catalonia)H-Index: 7
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
view all 6 authors...
Conducting polymers have been increasingly used as biologically interfacing electrodes for biomedical applications due to their excellent and fast electrochemical response, reversible doping-dedoping characteristics, high stability, easy processability, and biocompatibility. These advantageous properties can be used for the rapid detection and eradication of infections associated to bacterial growth since these are a tremendous burden for individual patients as well as the global healthcare syst...
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#1Jordi Sans (UPC: Polytechnic University of Catalonia)H-Index: 2
#2Vanesa SanzH-Index: 16
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
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Abstract The enhanced catalytic activity of permanently polarized hydroxyapatite, which is achieved using a thermally stimulated polarization process, largely depends on both the experimental conditions used to prepare crystalline hydroxyapatite from its calcium and phosphate precursors and the polarization process parameters. A mineral to brushite, which is an apatitic phase that can evolve to hydroxyapatite, is found at the surface of highly crystalline hydroxyapatite. It appears after chemica...
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#1Reza Zeinali (UPC: Polytechnic University of Catalonia)H-Index: 1
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 26
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
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Porous biodegradable scaffolds provide a physical substrate for cells allowing them to attach, proliferate and guide the formation of new tissues. A variety of techniques have been developed to fabricate tissue engineering (TE) scaffolds, among them the most relevant is the thermally-induced phase separation (TIPS). This technique has been widely used in recent years to fabricate three-dimensional (3D) TE scaffolds. Low production cost, simple experimental procedure and easy processability toget...
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The self-assembly behavior of chemoenzymatic high molecular weight (ca. 30 000 Da) poly-L-phenylalanine (ePLP) and the nano-morphologies thereof are investigated. Interestingly, this supramolecular ePLP changes from a non-ordered secondary structure when solubilized in water to an α-helix with the addition of only 1 vol% HFIP co-solvent, and at a relatively low concentration (0.5 mg mL−1). The results also indicate a temperature-dependent structural stabilization, wherein the self-assembly proce...
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#2Omid YousefzadeH-Index: 9
Last. Jordi PuiggalíH-Index: 39
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Melt electrospinning has been developed in the last decade as an eco-friendly and solvent-free process to fill the gap between the advantages of solution electrospinning and the need of a cost-effective technique for industrial applications. Although the benefits of using melt electrospinning compared to solution electrospinning are impressive, there are still challenges that should be solved. These mainly concern to the improvement of polymer melt processability with reduction of polymer degrad...
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#1Anna Puiggalí-Jou (UPC: Polytechnic University of Catalonia)H-Index: 7
#2Jesús Ordoño (Ciber)H-Index: 2
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
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Abstract We examine different approaches for the controlled release of L-lactate, which is a signaling molecule that participates in tissue remodeling and regeneration, such as cardiac and muscle tissue. Robust, flexible, and self-supported 3-layers films made of two spin-coated poly(lactic acid) (PLA) layers separated by an electropolymerized poly(3,4-ethylenedioxythiophene) (PEDOT) layer, are used as loading and delivery systems. Films with outer layers prepared using homochiral PLA and with n...
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Background and Objectives Pertussis is an infectious disease caused by the Gram-negative bacterium Bordetella pertussis. In Peru, actual public health programs indicate that vaccination against B. pertussis must be mandatory and generalized, besides all detected cases must be reported. The objective of this study was to determine the prevalence of B. pertussis among children under five years of age with a presumptive diagnosis of whopping cough in Cajamarca, a region located in northern Peru. Ma...
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