Naoto Tamura
Juntendo University
Internal medicineSurgeryPathologyUltrasoundMolecular biologyAntibodyDermatologyProspective cohort studyAdverse effectRheumatologyImmunologyVasculitisSystemic lupus erythematosusArthritisReactive arthritisInterstitial lung diseaseRheumatoid arthritisDermatomyositisDiseaseLupus nephritisPathogenesisMethotrexateIn patientMedicineGastroenterology
Publications 185
#1Takao FujiiH-Index: 32
#2Toshiya AtsumiH-Index: 15
Last. Michiaki TakagiH-Index: 27
view all 13 authors...
#1Mai Yoshida (Juntendo University)
#2Kentaro Minowa (Juntendo University)H-Index: 7
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 6 authors...
BackgroundHydroxychloroquine (HCQ) has been positioned as an anchor drug for systemic lupus erythematosus (SLE). There is evidence supporting the benefits of HCQ; however, the effect of additional ...
#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Keigo Saeki (Nara Medical University)H-Index: 24
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 9 authors...
Objectives: Malignant rheumatoid arthritis (MRA) is defined as rheumatoid arthritis (RA) with systemic vasculitis or other severe extra-articular manifestations. Japan has a nationwide database for...
#1Yoshinori Taniguchi (Kōchi University)H-Index: 19
#2Hirofumi Nishikawa (Kōchi University)H-Index: 3
Last. Shigeto Kobayashi (Juntendo University)H-Index: 25
view all 7 authors...
Reactive arthritis (ReA) is a form of sterile arthritis that occurs secondary to an extra-articular infection in genetically predisposed individuals. The extra-articular infection is typically an infection of the gastrointestinal tract or genitourinary tract. Infection-related arthritis is a sterile arthritis associated with streptococcal tonsillitis, extra-articular tuberculosis, or intravesical instillation of bacillus Calmette–Guerin (iBCG) therapy for bladder cancer. These infection-related ...
#1Yasushi Matsushita (Juntendo University)
#2Makio Kusaoi (Juntendo University)H-Index: 12
Last. Toshio Naito (Juntendo University)H-Index: 19
view all 10 authors...
We retrospectively analyzed the characteristics and outcomes of five patients with COVID-19 who were received glucocorticoid (with or without pulse therapy) and therapeutic plasma exchange. The efficacy of the treatment was determined by whether the patient was able to be transferred from the COVID-19 exclusive ICU to the general ward. In comparing patients who received prednisolone pulse therapy (3 cases) with those who did not (2 cases), 2/3 (66%) and 0/2 (0%) patients could be discharged from...
#1Makoto Hiki (Juntendo University)H-Index: 13
#2Yoko Tabe (Juntendo University)H-Index: 27
Last. Toshio Naito (Juntendo University)H-Index: 19
view all 15 authors...
Objectives To determine the seroprevalence of anti-SARS-CoV-2 IgG and IgM antibodies in symptomatic Japanese COVID-19 patients. Methods Serum samples (n = 114) from 34 COVID-19 patients with mild to critical clinical manifestations were examined. The presence and titers of IgG antibody for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were determined by a chemiluminescent microparticle immunoassay (CMIA) using Alinity i SARS-CoV-2 IgG and by an immunochromatographic (IC) IgM/IgG a...
#1Hiroki YasudoH-Index: 4
#2Taiki Ando (Juntendo University)H-Index: 2
Last. Jiro Kitaura (Juntendo University)H-Index: 36
view all 28 authors...
The nucleotide-binding domain leucine-rich repeat (LRR)-containing protein family pyrin domain (PYD)-containing protein 1 (NLRP1) forms an inflammasome complex with apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) and caspase-1. Inflammasome-activated caspase-1 cleaves pro-IL-1β or pro-IL-18 to produce its mature form and induces a type of cell death called pyroptosis through gasdermin D (GSDMD) activation.
#1Hideto Kameda (Toho University)H-Index: 33
#2Shigeto Kobayashi (Juntendo University)H-Index: 25
Last. Tetsuya Tomita (Osaka University)H-Index: 40
view all 7 authors...
Non-radiographic axial spondyloarthritis (nr-axSpA) is a subgroup of axial spondyloarthritis (axSpA) without fulfilling the modified New York criteria of sacroiliac joint radiographs for ankylosing spondylitis (AS). AS and nr-axSpA share various demographic and clinical features and disease burden, although sex and objective inflammatory findings such as elevated serum C-reactive protein level are slightly different between AS and nr-axSpA. Recently, diagnostic guidance for nr-axSpA in Japan was...
#1Satoshi Suzuki (Juntendo University)H-Index: 5
#2Keigo Ikeda (Juntendo University)H-Index: 14
Last. Shinji Morimoto (Juntendo University)H-Index: 18
view all 5 authors...
Anti-MDA5 antibody-positive clinically amyopathic dermatomyositis (CADM) is often complicated by rapidly progressive interstitial lung disease and is associated with poor prognosis. However, even though recurrence is reported to be infrequent if successful medical treatment is administered, the long-term prognosis remains unclear. In this case report, we examined the clinical features and treatment details of three patients with anti-MDA5 antibody-positive CADM with multiple recurrences during l...