Roger S. Blumenthal
Johns Hopkins University
Framingham Risk ScoreRisk assessmentInternal medicineEndocrinologyEthnic groupSurgeryCardiologyIntensive care medicinePhysical therapyAsymptomaticCholesterolCoronary artery diseaseDiseaseMetabolic syndromePopulationCoronary artery calciumMyocardial infarctionRisk factorDiabetes mellitusMedicine
Publications 954
#3Olufunmilayo H. Obisesan (MedStar Union Memorial Hospital)H-Index: 5
Abstract null null Objective null : Aspirin has been widely utilized over several decades for atherosclerotic cardiovascular disease (ASCVD) prevention among adults in the United States. We examined trends in aspirin use among adults aged ≥40 years from 1998 to 2019 and assessed factors associated with its use for primary and secondary ASCVD prevention. null null null Methods null : Using 1998–2019 Behavioral Risk Factor Surveillance System data, we obtained weighted prevalence of aspirin use am...
#1Michael R. Goetsch (Johns Hopkins University)H-Index: 1
#2Anjali A Wagle (Johns Hopkins University)
Last. Seamus P. Whelton (Johns Hopkins University)H-Index: 26
view all 7 authors...
#1Miguel Cainzos-Achirica (Houston Methodist Hospital)H-Index: 17
#2Dixitha Anugula (Creighton University)H-Index: 4
Last. Kausik K. Ray (Imperial College London)H-Index: 80
view all 12 authors...
ABSTRACT null null The Food and Drug Administration recommends prognostic enrichment of randomized controlled trials (RCTs), aimed at restricting the study population to participants most likely to have events and therefore derive benefit from a given intervention. The coronary artery calcium (CAC) score is powerful discriminator of cardiovascular risk, and in this review we discuss how CAC may be used to augment widely used prognostic enrichment paradigms of RCTs of add-on therapies in primary ...
#1Lochan M. Shah (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 3
#2Alison L. Wand (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 3
Last. Garima Sharma (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 10
view all 8 authors...
Early identification and mitigation of sex-specific cardiovascular disease risk factors is a potential trajectory-changing strategy to improve lifelong cardiovascular health in women. These sex-specific risk factors include adverse pregnancy outcomes, polycystic ovarian syndrome, and premature menopause. We start by discussing the impact and management of risk factors for adverse pregnancy outcomes as an upstream intervention for cardiovascular disease risk reduction and then address the long-te...
1 CitationsSource
#1Scott M. Grundy (UTSW: University of Texas Southwestern Medical Center)H-Index: 212
#2Neil J. Stone (NU: Northwestern University)H-Index: 56
Last. Laurence S. Sperling (Emory University)H-Index: 40
view all 11 authors...
Review of the US and European literature indicates that most patients at high risk for atherosclerotic cardiovascular disease (ASCVD are not treated with high-intensity statins, despite strong clinical-trial evidence of maximal statin benefit. High-intensity statins are recommended for 2 categories of patients: those with ASCVD (secondary prevention) and high-risk patients without clinical ASCVD. Most patients with ASCVD are candidates for high-intensity statins, with a goal for low-density lipo...
#1Daniel Chu (BCM: Baylor College of Medicine)H-Index: 8
#2Amjad M. Ahmed (National Guard Health Affairs)H-Index: 9
Last. Miguel Cainzos-Achirica (Houston Methodist Hospital)H-Index: 17
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PURPOSE We conducted this study to investigate the association of cardiorespiratory fitness and all-cause mortality among patients with chronic kidney disease. METHODS We studied a retrospective cohort of patients from the Henry Ford Health System who underwent clinically indicated exercise stress testing with baseline cardiorespiratory fitness and estimated glomerular filtration rate measurement. Cardiorespiratory fitness was expressed as metabolic equivalents of task, and kidney function was c...
#1Lochan M Shah (Johns Hopkins University)H-Index: 1
#2Bhavya Varma (Johns Hopkins University)
Last. Garima Sharma (Johns Hopkins University)H-Index: 10
view all 7 authors...
There is growing evidence that rural and racial disparities and social determinants of health (SDOH) impact adverse pregnancy outcomes (APOs) and overall maternal mortality in the United States. These APOs, such as preeclampsia, preterm birth, and intrauterine growth restriction, are in-turn associated with increased risk of future cardiovascular disease (CVD) later in life. Importantly, SDOH such as socioeconomic disadvantages, poor health literacy, transportation barriers, lack of access to ad...
#3Miguel Cainzos-Achirica (Johns Hopkins University)H-Index: 17
#4Omar Dzaye (Johns Hopkins University)H-Index: 14
Last. Michael J. Blaha (Johns Hopkins University)H-Index: 83
view all 8 authors...
#1David I. Feldman (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 11
#2J. Latina (JHUSOM: Johns Hopkins University School of Medicine)
Last. Armin Arbab-Zadeh (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 42
view all 5 authors...
Abstract null null The treatment of coronary artery disease (CAD), which is defined by stable anatomical atherosclerotic and functional alterations of epicardial vessels or microcirculation, focuses on managing intermittent angina symptoms and preventing major adverse cardiovascular events with optimal medical therapy. When patients with known CAD present with angina and no acute coronary syndrome, they have historically been evaluated with a variety of noninvasive stress tests that utilize elec...
1 CitationsSource