Adrianus P. Wijnmaalen
Leiden University Medical Center
Interquartile rangeInternal medicineSurgeryCardiologyRandomized controlled trialHazard ratioSinus rhythmCatheter ablationVentricular tachycardiaCryoablationInfarctionHeart failureTetralogy of FallotCardiomyopathyAblationVentricleAtrial fibrillationElectrocardiographyHeart diseaseTachycardiaPulmonary veinCatheterIn patientElectroanatomic mappingMyocardial infarctionMedicineEjection fraction
36Publications
13H-index
883Citations
Publications 36
Newest
#1F. Kece (LUMC: Leiden University Medical Center)H-Index: 3
#2Marta de Riva (LUMC: Leiden University Medical Center)H-Index: 10
Last. Serge A. Trines (LUMC: Leiden University Medical Center)H-Index: 20
view all 8 authors...
Background Predicting early reconnection/dormant conduction (ERC) immediately after pulmonary vein isolation (PVI) can avoid a waiting period with adenosine testing. Objective To identify procedural and biophysical parameters predicting ERC. Methods Consecutive atrial fibrillation (AF) patients undergoing a first cryoballoon ablation (Arctic Front Advance) between 2014 and 2017 were included. ERC was defined as manifest or dormant pulmonary vein (PV) reconnection with adenosine 30 minutes after ...
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#1Y. Naruse (LUMC: Leiden University Medical Center)H-Index: 3
#2Marta de Riva (LUMC: Leiden University Medical Center)H-Index: 10
Last. Katja Zeppenfeld (LUMC: Leiden University Medical Center)H-Index: 57
view all 8 authors...
BACKGROUND J-waves and fragmented-QRS (fQRS) on surface ECGs have been associated with the occurrence of ventricular tachyarrhythmias. Whether these non-invasive parameters can also predict ventricular tachycardia (VT) recurrence after radiofrequency catheter ablation (RFCA) is unknown. Of interest, patients with a wide QRS-complex have been excluded from clinical studies on J-waves, although a J-wave like pattern has been described for wide QRS. METHODS We retrospectively included 168 patients ...
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#1Marta de Riva (LUMC: Leiden University Medical Center)H-Index: 10
#2Y. Naruse (LUMC: Leiden University Medical Center)H-Index: 3
Last. Katja Zeppenfeld (LUMC: Leiden University Medical Center)H-Index: 57
view all 10 authors...
AIMS In patients with post-myocardial infarction (post-MI) ventricular tachycardia (VT), the presence of myocardial calcification (MC) may prevent heating of a subepicardial VT substrate contributing to endocardial ablation failure. The aims of this study were to assess the prevalence of MC in patients with post-MI VT and evaluate the impact of MC on outcome after endocardial ablation. METHODS AND RESULTS In 158 patients, the presence of MC was retrospectively assessed on fluoroscopy recordings ...
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#1Micaela Ebert (LUMC: Leiden University Medical Center)H-Index: 8
#2Adrianus P. Wijnmaalen (LUMC: Leiden University Medical Center)H-Index: 13
Last. Katja Zeppenfeld (LUMC: Leiden University Medical Center)H-Index: 57
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Abstract Objectives This study aimed to assess the frequency of (likely) pathogenic variants (LP/Pv) among dilated cardiomyopathy (DCM) ventricular tachycardia (VT) patients referred for CA and their impact on procedural outcome and long-term prognosis. Background The prevalence of genetic variants associated with monomorphic VT among DCM is unknown. Methods Ninety-eight consecutive patients (age 56 ± 15 years; 84% men, left ventricular ejection fraction [LVEF] 39 ± 12%) referred for DCM-VT abla...
3 CitationsSource
#1Carine F.B. van Huls van Taxis (LUMC: Leiden University Medical Center)H-Index: 10
#2Katja Zeppenfeld (LUMC: Leiden University Medical Center)H-Index: 57
Last. Adrianus P. Wijnmaalen (LUMC: Leiden University Medical Center)H-Index: 13
view all 4 authors...
1 CitationsSource
#1Alexander F.A. Androulakis (LUMC: Leiden University Medical Center)H-Index: 7
#2Katja Zeppenfeld (LUMC: Leiden University Medical Center)H-Index: 57
Last. Qian Tao (LUMC: Leiden University Medical Center)H-Index: 22
view all 11 authors...
Abstract Objectives This study proposed entropy as a new late gadolinium enhanced cardiac magnetic resonance–derived parameter to evaluate tissue inhomogeneity, independent of signal intensity thresholds. This study hypothesized that entropy within the scar is associated with ventricular arrhythmias (VAs), whereas entropy of the entire left ventricular (LV) myocardium is associated with mortality. Background In patients after myocardial infarction, the heterogeneity of fibrosis determines the su...
14 CitationsSource
#1F. Kece (LUMC: Leiden University Medical Center)H-Index: 3
#2Marta de Riva (LUMC: Leiden University Medical Center)H-Index: 10
Last. Serge A. Trines (LUMC: Leiden University Medical Center)H-Index: 20
view all 8 authors...
INTRODUCTION: Efficacy of cryoballoon ablation depends on balloon-tissue contact and ablation duration. Prolonged duration may increase extracardiac complications. The aim of this study is to determine the optimal additional ablation duration after acute pulmonary vein isolation (PVI). METHODS: Consecutive patients with paroxysmal AF were randomized to three groups according to additional ablation duration (90, 120, or 150 seconds) after acute PVI (time-to-isolation). Primary outcome was reconne...
3 CitationsSource
#1Katja E. Odening (UM: Maastricht University)H-Index: 20
#2Sebastian DeißH-Index: 1
Last. Hikmet Yorgun (Hacettepe University)H-Index: 23
view all 12 authors...
Atrial fibrillation (AF) is the clinically most prevalent rhythm disorder with large impact on quality of life and increased risk for hospitalizations and mortality in both men and women. In recent years, knowledge regarding epidemiology, risk factors, and patho-physiological mechanisms of AF has greatly increased. Sex differences have been identified in the prevalence, clinical presentation, associated comorbidities, and therapy outcomes of AF. Although it is known that age-related prevalence o...
19 CitationsSource
#1F. Kece (LUMC: Leiden University Medical Center)H-Index: 3
#2Eline F. Bruggemans (LUMC: Leiden University Medical Center)H-Index: 12
Last. Serge A. Trines (LUMC: Leiden University Medical Center)H-Index: 20
view all 14 authors...
Abstract Objectives The purpose of this study was to randomly compare the incidence of asymptomatic cerebral embolism (ACE) between the second-generation pulmonary vein ablation catheter (PVAC Gold) and the irrigated Thermocool catheter. Background Pulmonary vein isolation (PVI) with the pulmonary vein ablation catheter (PVAC) is associated with ACE. The PVAC Gold was designed to avoid this complication. Methods Patients with paroxysmal atrial fibrillation were randomized 1:1 to PVI with the PVA...
8 CitationsSource
#1Y. Naruse (LUMC: Leiden University Medical Center)H-Index: 3
#2F. Kece (LUMC: Leiden University Medical Center)H-Index: 3
Last. Serge A. Trines (LUMC: Leiden University Medical Center)H-Index: 20
view all 9 authors...
Background: A novel non-fluoroscopic catheter tracking system (Mediguide) can be used in combination with a 3D mapping system for atrial fibrillation (AF) ablation. However, the benefit on radiation exposure of the Mediguide system compared to other ablation systems is unknown. Methods: We retrospectively enrolled consecutive 73 patients (51 men; 59±11 years; 60 paroxysmal AF) undergoing pulmonary vein isolation by the same operator. Radiation time, radiation effective dose, procedure time, AF r...
2 CitationsSource