Georg Gahn
Dresden University of Technology
Internal medicineRadiologySurgeryUltrasoundCardiologyMiddle cerebral arteryDuplex ultrasonographyCarotid artery diseaseOcclusionVascular diseaseDigital subtraction angiographyInternal carotid arteryThrombolysisGrading (tumors)NeuroradiologyStenosisAngioplastyAngiographyCarotid endarterectomyIn patientDuplex sonographyAnesthesiaStrokeIschemiaText miningMedicine
60Publications
16H-index
782Citations
Publications 58
Newest
#1Volker Puetz (TUD: Dresden University of Technology)H-Index: 23
#2Ulf BodechtelH-Index: 16
Last. Ruediger von KummerH-Index: 14
view all 15 authors...
Objective: To determine the reliability and therapeutic impact of standardized cerebral CT evaluation and quantification of early ischemic changes (EIC) with the Alberta Stroke Program Early CT Score (ASPECTS) by stroke neurologists in the Stroke Eastern Saxony Network (SOS-NET), which provides telemedical consultations for patients with acute ischemic stroke. Methods: Two neuroradiologists re-evaluated all CT scans of consecutive SOS-NET patients in 2009 blinded to clinical information providin...
45 CitationsSource
#1Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
#2U. BeckerH-Index: 5
Last. Georg GahnH-Index: 16
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BACKGROUND The best therapeutic approach in patients with acute basilar artery occlusion (BAO) remains unclear. We report the results of a combined treatment approach with intravenous (IV) abciximab and intraarterial (IA) tissue plasminogen activator (tPA) in these patients. METHODS We prospectively studied patients with acute BAO on CT-angiography or MR-angiography. We treated patients with IV abciximab followed by IA thrombolysis with tPA. Primary outcome was partial or complete recanalization...
26 CitationsSource
#1Lars Mense (TUD: Dresden University of Technology)H-Index: 4
#2Manja Reimann (TUD: Dresden University of Technology)H-Index: 19
Last. Tjalf Ziemssen (TUD: Dresden University of Technology)H-Index: 53
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Background: Carotid endarterectomy (CEA) is the first-line treatment in severe carotid stenosis to prevent stroke. Because of methodological limitations, the acute impact of CEA on baroreflex function and cerebral autoregulation is not well defined and was therefore investigated by applying a novel algorithm. Methods and Results: Systemic arterial blood pressure, ECG and respiration during metronomic breathing and Valsalva maneuver were continuously recorded in 18 patients with carotid stenosis ...
19 CitationsSource
#1Georg Gahn (TUD: Dresden University of Technology)H-Index: 16
#2Kristian Barlinn (TUD: Dresden University of Technology)H-Index: 21
Last. U. Becker (TUD: Dresden University of Technology)H-Index: 5
view all 7 authors...
Background – In patients with acute middle cerebral artery (MCA) occlusion, recanalization rates with intravenous (IV) recombinant tissue plasminogen activator (rtPA) are limited. Aim– We evaluated the feasibility and safety of combined IV thrombolysis with abciximab and reduced dose rtPA in a 3- to 6-h time window. Methods – We prospectively (March 2002 to February 2005) studied patients with symptomatic MCA occlusion on computed tomography (CT) angiography and absence of major early ischemic c...
6 CitationsSource
#1Volker Puetz (TUD: Dresden University of Technology)H-Index: 23
#2P N SylajaH-Index: 25
Last. Andrew M. DemchukH-Index: 10
view all 9 authors...
BACKGROUND AND PURPOSE: The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) is a 10-point grading system to quantify ischemic changes in the posterior circulation. We analyzed whether pc-ASPECTS on CT angiography (CTA) source images (CTASI) predicted the final infarct extent and hemorrhagic transformation (HT) rate in patients with basilar artery occlusion. MATERIALS AND METHODS: A pc-ASPECTS score of 10 indicates absence of visible ischemic changes in the posterior circ...
35 CitationsSource
Abstract Background and purpose To date, pre-treatment with anti-platelet agents does not constitute a contraindication for thrombolysis in acute ischemic stroke. We tested the hypothesis that combined pre-treatment with aspirin and clopidogrel is a risk factor for thrombolysis-related symptomatic intracerebral hemorrhage (sICH). Methods We retrospectively studied patients with acute ischemic stroke receiving standard IV thrombolytic therapy with rt-PA in our institution. Exclusion criteria were...
19 CitationsSource
#1Volker PuetzH-Index: 23
#2Imanuel DzialowskiH-Index: 26
Last. R. von KummerH-Index: 30
view all 5 authors...
BACKGROUND AND PURPOSE: The posterior circulation Acute Stroke Prognosis Early CT Score (pcASPECTS) is a 10-point grading system to quantify ischemic changes in the posterior circulation. We analyzed whether pc-ASPECTS on CT angiography (CTA) source images (CTASI) predicted the final infarct extent and hemorrhagic transformation (HT) rate in patients with basilar artery occlusion. MATERIALS AND METHODS: A pc-ASPECTS score of 10 indicates absence of visible ischemic changes in the posterior circu...
While incidence of stroke in patients 55 to 64 years of age is 2-3 per 1 000 people and per year, this rate is 10fold higher in patients 85 years of age or above. Concomitant cardiovascular diseases, e. g. arterial hypertension, diabetes mellitus and hypercholesterinaemia, increase the risk for stroke. Both prevalence and incidence increase with age. Early treatment and continuous optimisation of these risk factors can prevent stroke. Prevention of cerebro-vascular complications reduces the deve...
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#1Volker Puetz (TUD: Dresden University of Technology)H-Index: 23
#2P N SylajaH-Index: 25
Last. Andrew M. DemchukH-Index: 6
view all 15 authors...
Background and Purpose— Quantification of early ischemic changes (EIC) may predict functional outcome in patients with basilar artery occlusion (BAO). We tested the validity of a novel CT score, the posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS). Methods— Pc-ASPECTS allots the posterior circulation 10 points. Two points each are subtracted for EIC in midbrain or pons and 1 point each for EIC in left or right thalamus, cerebellum or PCA-territory, respectively. We studie...
187 CitationsSource
#1Georg GahnH-Index: 16
#2U. BeckerH-Index: 5
view all 9 authors...
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