Andrew Scarsbrook
Leeds Teaching Hospitals NHS Trust
CancerInternal medicineRadiologyPET-CTSurgeryPathologyMagnetic resonance imagingOncologyTomographyFunctional imagingMedical physicsPositron emission tomographyLung cancerHead and neck squamous-cell carcinomaCarcinomaDiseaseMalignancyMEDLINEScintigraphyNuclear medicineIn patientFdg pet ctRadiation therapyComputed tomographyMedicine
Publications 134
When biochemical recurrence (BCR) of prostate cancer is suspected, early and accurate localization of metastases facilitates treatment when tumors are small and most amenable to localized therapy, and may guide clinicians in making management plans regarding salvage therapy. Here, we present results of a preplanned analysis of the FALCON trial (NCT02578940), which assessed the impact of PET/CT imaging with 18F-fluciclovine on clinical management choices for men with BCR of prostate cancer.
#1D. Bird (St James's University Hospital)H-Index: 4
#2Chirag Patel (St James's University Hospital)H-Index: 14
Last. Robin Prestwich (St James's University Hospital)H-Index: 27
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Abstract Background and purpose Involved site radiotherapy clinical target volume (CTV) for lymphoma requires an expansion to account for the absence of radiotherapy treatment-position pre-chemotherapy imaging, which is not widely implemented. This prospective imaging study aims to quantify CTV expansion required for neck radiotherapy. Materials and methods 10 patients from a prospective single centre imaging study underwent a pre-chemotherapy FDG-PET-CT in both the diagnostic and radiotherapy t...
6 CitationsSource
#1F. SlevinH-Index: 2
#2Ekin ErmişH-Index: 6
Last. Robin PrestwichH-Index: 27
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Introduction: The accuracy of response assessment positron emission tomography (PET)-computed tomography (CT) following radiotherapy with or without chemotherapy for laryngeal/hypopharyngeal squamous cell carcinoma is uncertain. Methods: In all, 35 patients with laryngeal or hypopharyngeal squamous cell carcinoma who were treated between 2009 and 2014 with (chemo)radiotherapy were identified. The accuracy of response assessment PET-CT was made by correlation with clinical follow-up and pathologi...
2 CitationsSource
#1Robert Chuter (St James's University Hospital)H-Index: 19
#1Robert Chuter (St James's University Hospital)H-Index: 8
Last. Richard Speight (St James's University Hospital)H-Index: 10
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Abstract Background and purpose To assess the accuracy of gross tumour volume (GTV) delineation for head and neck squamous cell carcinoma (HNSCC) using a diagnostic position MRI (MRI-D) deformably registered to the planning CT (pCT), by comparison with a dedicated planning position MRI (MRI-RT). Material and methods Fourteen patients with HNSCC underwent a T1-weighted MRI-D and MRI-RT. A reference GTV was defined as that delineated on MRI-RT rigidly registered to pCT. GTVs were delineated on: MR...
17 CitationsSource
#1H. Motara (University of Leeds)H-Index: 1
#2T. OlusogaH-Index: 1
Last. Fahmid U. Chowdhury (Leeds Teaching Hospitals NHS Trust)H-Index: 18
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Aim To evaluate the clinical impact of combined 2-[ 18 F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography/computed tomography (PET/CT) brain imaging performed in selected patients with cognitive impairment at a tertiary referral centre in the UK, and to assess the accuracy of FDG PET/CT to correctly establish the diagnosis of Alzheimer's dementia (AD) in "real-world" clinical practice. Methods and materials Using an institutional radiology database, 136 patients were identified for i...
4 CitationsSource
#1Finbar SlevinH-Index: 3
#2Sriram VaidyanathanH-Index: 15
Last. Robin PrestwichH-Index: 27
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#1G. Ward (Leeds Teaching Hospitals NHS Trust)H-Index: 1
#1G. Ward (Leeds Teaching Hospitals NHS Trust)H-Index: 1
Last. Ganesh Radhakrishna (Leeds Teaching Hospitals NHS Trust)H-Index: 10
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Abstract Aims To investigate the use of image co-registration in incorporating diagnostic positron emission tomography-computed tomography (PET-CT) directly into the radiotherapy treatment planning pathway, and to describe the pattern of local recurrence relative to the PET-avid volume. Materials and methods Fourteen patients were retrospectively identified, six of whom had local recurrence. The accuracy of deformable image registration (DIR) and rigid registration of the diagnostic PET-CT and r...
6 CitationsSource
#1Andrew Scarsbrook (St James's University Hospital)H-Index: 29
#2Sally Barrington (St Thomas' Hospital)H-Index: 49
Combined positron-emission tomography and computed tomography (PET-CT) has taken the oncological world by storm since being introduced into the clinical domain in the early 21st century and is firmly established in the management pathway of many different tumour types. Non-oncological applications of PET-CT represent a smaller but steadily growing area of interest. PET-CT continues to be the focus of a large number of research studies and keeping up-to-date with the literature is important but r...
9 CitationsSource
#1Paula Ghaneh (University of Liverpool)H-Index: 61
#2Wai Lup Wong (Mount Vernon Hospital)H-Index: 5
Last. John P. Neoptolemos (University of Liverpool)H-Index: 124
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1 CitationsSource
#1Paula Ghaneh (University of Liverpool)H-Index: 61
#2Wai Lup Wong (Mount Vernon Hospital)H-Index: 5
Last. John P. Neoptolemos (University of Liverpool)H-Index: 124
view all 20 authors...
4008Background: Pancreatic cancer diagnosis and staging is challenging. FDG PET/CT adds anatomic localization to functional data. The aim of this study was to determine the impact of FDG PET/CT in ...
8 CitationsSource