Gabriel Alejandro Martínez-Castañón
Universidad Autónoma de San Luis Potosí
Analytical chemistryNuclear chemistryTransmission electron microscopyNanoparticleEnamel paintComposite materialNanotechnologyAqueous solutionChemistryMaterials scienceDentistryMolarStreptococcus mutansChitosanAntibacterial activitySilver nanoparticleChemical engineeringAntimicrobialAntibioticsBacteriaBiofilmMedicineMicrobiology
81Publications
19H-index
1,903Citations
Publications 79
Newest
#1Marco Felipe Salas-Orozco (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2Nereyda Niño-Martínez (Universidad Autónoma de San Luis Potosí)H-Index: 12
Last. Horacio Bach (UBC: University of British Columbia)H-Index: 28
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Nanoparticles (NPs) have been widely studied as an alternative to antibiotic use due to their antimicrobial properties at lower concentrations. Enterococcus faecalis is a facultative Gram-positive microorganism inhabiting the gastrointestinal tract of humans and animals. It can also be present in other environments such as the oral cavity, water, sewage, soil, and food. AIMS We evaluated whether E. faecalis could develop resistance to AgNPs after exposure to sub-lethal concentrations of the NPs....
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#1Marco Felipe Salas Orozco (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2Nereyda Niño-Martínez (Universidad Autónoma de San Luis Potosí)H-Index: 12
Last. Miguel Angel Angel Casillas Santana (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 1
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Background and Objectives: The aim of this systematic review is to summarize the current data about the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its entry factors in oral tissues and cells. Materials and Methods: This systematic review was carried out based on the Preferred Reporting Items for a Systematic Review and Meta-Analysis (PRISMA). Three databases were analyzed (Pubmed, Web of science and Scopus) by three independent researchers. From the 18 identifie...
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ABSTRACT Researchers have reported false positive/negative results of the cold test in the diagnosis of pulpitis. Knowledge of the correlation between results of the cold test and proteins could aid in decreasing the frequency of incorrect diagnosis. To associate the levels of matrix metalloproteinase-8 (MMP-8) with the responses (in seconds) to the cold test in teeth diagnosed with reversible and irreversible pulpitis.A cross-sectional study was performed. A total of 150 subjects were evaluated...
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#1Montserrat Lopez-Carrizales (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2E. Mendoza-Mendoza (Universidad Autónoma de San Luis Potosí)H-Index: 7
Last. Fidel Martinez-Gutierrez (Universidad Autónoma de San Luis Potosí)H-Index: 13
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Abstract The purpose of this study was to generate novel chitosan hydrogels (CHs) loaded with silver nanoparticles (AgNPs) and ampicillin (AMP) to prevent early formation of biofilms. AgNPs and CHs were characterized by UV-Vis, DLS, TEM, rheology, FT-IR, Raman, and SEM. The antibiofilm effect of the formulations was investigated against four multidrug-resistant and extensively drug-resistant pathogens using a colony biofilm, a high cell density and gradients model. Also, their hemostatic propert...
1 CitationsSource
#1Samuel Salazar-García (Universidad Autónoma de San Luis Potosí)H-Index: 6
#2Jose Fernando García-Rodrigo (Universidad Autónoma de San Luis Potosí)H-Index: 1
Last. Carmen G. Gonzalez (Universidad Autónoma de San Luis Potosí)H-Index: 33
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Silver nanoparticles (AgNPs) induced specific cell toxicity, and they are used as a tool for the study of several pathologies such as cancer. This work aimed to elucidate the toxic effect of < 10-nm silver nanoparticles (AgNPs) and zinc chloride (ZnCl2) in different administration orders on C6 rat glioma cells, as a biological model of study. C6 rat glioma cells were exposed to increasing concentrations of AgNPs (10–100 μg/mL) in the presence or absence of ZnCl2 (10–50 μg/mL) for 24 h. AgNPs or ...
1 CitationsSource
BACKGROUND: Two polymorphisms in the macrophage migration inhibitory factor (MIF) gene have been associated with inflammatory diseases (-794 CATT5-8 and -173G>C); however, so far there are no reports of studies related to oral health. OBJECTIVES: To genotype the -794 CATT5-8 and -173G>C MIF polymorphisms in Mexican patients with apical periodontitis as a genetic risk of exacerbation. MATERIAL AND METHODS: The study involved 120 patients with apical periodontitis: 60 with a diagnosis of acute api...
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#1Carlos Bermúdez‐Jiménez (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2Nereyda Niño-Martínez (Universidad Autónoma de San Luis Potosí)H-Index: 12
Last. Gabriel Alejandro Martínez-Castañón (Universidad Autónoma de San Luis Potosí)H-Index: 19
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: Biofilms are matrices synthesized by bacteria containing polysaccharides, DNA, and proteins. The development of biofilms in infectious processes can induce a chronic inflammatory response that may progress to the destruction of tissues. The treatment of biofilms is difficult because they serve as a bacterial mechanism of defense and high doses of antibiotics are necessary to treat these infections with limited positive results. It has been demonstrated that photothermal therapy using gold nano...
5 CitationsSource
#1Carlos Bermúdez‐Jiménez (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2Marc G. Romney (UBC: University of British Columbia)H-Index: 17
Last. Horacio Bach (UBC: University of British Columbia)H-Index: 28
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Abstract Plasmonic photothermal therapy (PPTT) has been used as an alternative to chemotherapy for the elimination of resistant microorganisms; however, its in situ evaluation has not been well studied. In the present study, we assessed the antimicrobial activity of a chitosan-based hydrogel embedded with gold nanorods (Ch/AuNRs) using a low power infrared diode laser. The antibacterial activity was measured in both Gram-positive and –negative strains, including clinical isolates of multidrug-re...
7 CitationsSource
#1Marco Felipe Salas-Orozco (Universidad Autónoma de San Luis Potosí)H-Index: 2
#2Nereyda Niño Martinez (Universidad Autónoma de San Luis Potosí)H-Index: 2
Last. Facundo Ruiz (Universidad Autónoma de San Luis Potosí)H-Index: 3
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Introduction. Silver nanoparticles are used in endodontics due to their antimicrobial activity, although it is considered that bacteria are unable to develop resistance to silver nanoparticles. Silver resistance genes have been related to resistance to nanoparticles and antibiotics. The presence of these resistance genes has not been studied in endodontic bacteria. The objective of this study is to report the prevalence of silver resistance genes in endodontic bacteria. Methods. The selected tee...
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: The aim of the present study was to identify the relationship between the expression of calcitonin gene-related peptide (CGRP) and the responses of pulp sensitivity tests in healthy pulps and irreversible pulps by performing a cross-sectional study on patients. Two hundred subjects were evaluated. A total of 75 subjects complied with the criteria. The participants were divided into two groups: a) Healthy pulp (subjects [n = 35] having posterior teeth with clinically normal pulp tissue), and b)...
1 CitationsSource