Makoto Naganuma
Keio University
Internal medicineRadiologySurgeryAdverse effectImmunologyColitisInfliximabCapsule endoscopyInflammatory bowel diseaseColonoscopyEndoscopyDiseaseCrohn's diseaseAbdominal surgeryUlcerative colitisIn patientHepatologyMedicineBiologyGastroenterology
271Publications
36H-index
3,521Citations
Publications 270
Newest
#1Takumi FujimuraH-Index: 7
#2Yohei YamadaH-Index: 10
Last. Naoki HosoeH-Index: 19
view all 0 authors...
Maintenance treatment with infliximab for ulcerative ileitis after intestinal transplantation: A case report
Source
#1Takashi Ito (Kansai Medical University)H-Index: 4
#2Masaaki Shimatani (Kansai Medical University)H-Index: 17
Last. Makoto Naganuma (Kansai Medical University)H-Index: 36
view all 7 authors...
Source
#2Yusuke YoshimatsuH-Index: 3
Last. Takanori KanaiH-Index: 70
view all 6 authors...
Source
#1Tomomitsu TaharaH-Index: 28
#2Sayumi TaharaH-Index: 6
Last. Naoki OhmiyaH-Index: 36
view all 6 authors...
Source
#1Tomomitsu TaharaH-Index: 28
#2Sayumi TaharaH-Index: 6
Last. Naoki OhmiyaH-Index: 36
view all 6 authors...
Source
#1Akiyoshi Ikebata (Keio: Keio University)H-Index: 1
#2Masayuki Shimoda (Keio: Keio University)H-Index: 29
Last. Yasushi Iwao (Keio: Keio University)H-Index: 32
view all 14 authors...
Background and study aims Recent advances in endoscopic equipment and diagnostic techniques have improved the detection of dysplasia in the inflamed mucosa of patients with ulcerative colitis (UC). However, it remains difficult to endoscopically identify flat-type dysplasia which has been formerly recognized as invisible dysplasia. Patients and methods In this retrospective, single-center study, we endoscopically identified 10 cases of flat-type-predominant dysplasia by targeted biopsy among 38 ...
Source
#1Motonobu Maruo (Kansai Medical University)
#2Tomomitsu Tahara (Kansai Medical University)H-Index: 2
Last. Makoto Naganuma (Kansai Medical University)H-Index: 36
view all 16 authors...
RATIONALE Brunner gland hamartoma (BGH) is a rare tumor of the duodenum. Although BGH is a benign tumor, larger lesion with gastrointestinal symptoms requires tumor removal. We report a giant BGH, successfully treated by endoscopic excision followed by transanal retrieval. PATIENT CONCERNS A 38-year-old woman complained of severe anemia, tarry stool, and vomiting. DIAGNOSES Esophagogastroduodenoscopy (EGD) showed a pedunculated giant submucosal mass at the duodenal bulb. INTERVENTIONS We attempt...
Source
#1Manami Ikemune (Kansai Medical University)H-Index: 2
#2Kazushige Uchida (Kōchi University)H-Index: 14
Last. Kazuichi Okazaki (Kansai University)H-Index: 1
view all 9 authors...
Abstract Background /Object: Some patients with type 1 autoimmune pancreatitis (AIP), the pancreatic manifestation of IgG4-related disease, have normal serum IgG4. The aim of this study is to investigate the diagnostic value of measuring serum free light chains (FLCs) in type 1 AIP. Materials and methods Thirty-seven patients with type 1 AIP, and 21 healthy, 17 alcoholic chronic pancreatitis (ACP), 21 idiopathic chronic pancreatitis (ICP) and 20 pancreatic cancer (PC) patients were enrolled. Ser...
Source
#1Kanehiko Suwa (Kansai Medical University)H-Index: 2
#2Toshihito Seki (Kansai Medical University)H-Index: 32
Last. Makoto Naganuma (Kansai Medical University)H-Index: 36
view all 9 authors...
PURPOSE To evaluate the efficacy and safety of radiofrequency ablation (RFA) and new-generation microwave ablation (MWA) for the treatment of hepatocellular carcinoma (HCC). METHODS The propensity score matching method was applied to patients with HCC treated with MWA (93 patients) or RFA (156 patients) at a single institution from January 2014 to April 2020. The local tumor progression (LTP), intrahepatic distant recurrence (IDR), and recurrence-free survival (RFS) of the two matched therapies ...
Source
#1Katsuyoshi Matsuoka (Toho University)H-Index: 33
#2Makoto Naganuma (Kansai Medical University)H-Index: 36
Last. Takanori Kanai (Keio: Keio University)H-Index: 70
view all 11 authors...
BACKGROUND AND AIM E6011 is a humanized monoclonal antibody targeting fractalkine (FKN), a CX3C chemokine, which regulates leukocyte trafficking during inflammation. We evaluated the safety and pharmacokinetic profile of E6011 in patients with Crohn's disease (CD), and also performed preliminary pharmacodynamic (PD) and efficacy assessments. METHODS This study included a 12-week multiple ascending dose (MAD) phase (2, 5, 10, and 15 mg/kg intravenously every 2 weeks, n = 6, 8, 7, and 7, respectiv...
1 CitationsSource