Alessia Farneti
University of Perugia
Internal medicineRadiologyUrologySurgeryOncologyPerfusionDiffusion MRIProspective cohort studyProstateHead and neck cancerBrachytherapyConcomitantProstatectomyProstate cancerHormone therapyHigh-Dose Rate BrachytherapyPartial Breast IrradiationToxicityNuclear medicineRadiation therapyBreast cancerMedicineIntravoxel incoherent motion
36Publications
9H-index
163Citations
Publications 35
Newest
PURPOSE The purpose of this study is to evaluate inter- and intra-fraction organ motion as well as to quantify clinical target volume (CTV) to planning target volume (PTV) margins to be adopted in the stereotactic treatment of early stage glottic cancer. METHODS AND MATERIALS Stereotactic body radiotherapy (SBRT) to 36 Gy in 3 fractions was administered to 23 patients with early glottic cancer T1N0M0. Patients were irradiated with a volumetric intensity modulated arc technique delivered with 6 M...
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#1Giuseppe SanguinetiH-Index: 37
#2Raul PelliniH-Index: 21
Last. Valeria LandoniH-Index: 20
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AIM Because the clinical feasibility of stereotactic body radiotherapy (SBRT) for early glottic cancer (T1) is controversial, we report dosimetric results in 27 consecutive patients from a prospective phase I and II study that started in 2017. METHODS In our approach, only the parts of the true vocal cord containing cancer and those immediately adjacent are planned to be treated to 36 Gy and 30 Gy, respectively, in 3 fractions. Several dosimetric metrics for both target volumes and organs at ris...
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Abstract Purpose To assess the toxicity profile of prostate cancer stereotactic radiotherapy (SBRT) in 3 fractions. Methods and Materials This is a prospective, multicenter phase II toxicity study enrolling patients with low to favorable intermediate risk prostate cancer. Before simulation 3-4 fiducial markers along with a rectal spacer were placed. The target (prostate only) was prescribed 40 Gy, while the maximum dose to the urethra was limited to 33 Gy with the highest priority at planning; l...
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#1Giuseppe SanguinetiH-Index: 37
#2Luca BertiniH-Index: 1
Last. Valeria LandoniH-Index: 20
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OBJECTIVE: To assess the predictive role of response on dynamic contrast enhancement on magnetic resonance imaging (DCE-MRI) of visible local lesions in the setting of salvage radiotherapy (sRT) after radical prostatectomy. METHODS: All patients referred for sRT for biochemical failure after radical prostatectomy from February 2014 to September 2016 were considered eligible if they had been restaged with DCE-MRI and had been found to have a visible lesion in the prostatic bed, but no distant/nod...
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Cachexia is a complex metabolic syndrome that determines a severe body weight loss characterized by a marked reduction in muscle mass. About 80% of patients with advanced cancer develop cachexia due to both the tumor itself and cancer treatment (radiotherapy and/or chemotherapy), which is associated to a worse prognosis. Despite its clinical relevance, this syndrome is still under-diagnosed and it lacks effective treatments. Radio-chemotherapy treatment is essential in patients with advanced hea...
5 CitationsSource
#1Antonello VidiriH-Index: 24
#2Emma GangemiH-Index: 5
Last. Simona MarziH-Index: 18
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Objectives To investigate the correlation between histogram-based Dynamic Contrast-Enhanced magnetic resonance imaging (DCE-MRI) parameters and positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG-PET) values in oropharyngeal squamous cell carcinoma (OPSCC), both in primary tumors (PTs) and in metastatic lymph nodes (LNs). Methods 52 patients with a new pathologically-confirmed OPSCC were included in the present retrospective cohort study. Imaging including DCE-MRI and 18F-FDG PET/C...
2 CitationsSource
Abstract Background and purpose Dose-volume objectives for the rectum have been proposed to limit long term toxicity after moderately hypofractionated radiotherapy (MHRT) for localized prostate cancer. The purpose of the present study is to validate and possibly refine dose volume objective for the rectal wall after 20-fraction MHRT. Materials and methods All patients treated by 20-fraction MHRT at a single Institution were identified and relative rectal wall (%RW) DVH retrieved. The endpoint of...
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#1Cristiana BergaminiH-Index: 20
#2Stefano CavalieriH-Index: 8
Last. Lisa Licitra (University of Milan)H-Index: 67
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Salivary duct carcinoma (SDC) is a rare and aggressive malignancy with a high mortality and poor response to treatment in the advanced setting. Human epidermal growth factor 2 (HER2) can be amplified in a fraction of SDC. We describe the case of HER2+ metastatic SDC of the submandibular gland in a young pregnant woman treated by multimodal treatment (chemotherapy, radiotherapy and targeted therapy). During pregnancy, a 27-year-old woman developed SDC of the left submandibular gland with lung and...
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#1Antonello VidiriH-Index: 24
#2Simona MarziH-Index: 18
Last. Giuseppe SanguinetiH-Index: 37
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Abstract Purpose To investigate the relationships between imaging parameters derived from intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and HPV status in oropharyngeal squamous cell carcinoma (OPSCC). Materials and Methods 73 patients with a new diagnosis of OPSCC were enrolled in the present study. MRI including IVIM-DWI with nine b value (range 0–800 s/mm2) was acquired in all patients. Primary tumor (PT) and the largest metastatic lymph node (LN), if present, were volumet...
4 CitationsSource
#1Giuseppe SanguinetiH-Index: 37
#2Alessia FarnetiH-Index: 9
Last. Alessandro MagliH-Index: 12
view all 10 authors...
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