Evangelos Oikonomou
National and Kapodistrian University of Athens
Internal medicineEndocrinologySurgeryPathologyCardiologyArterial stiffnessInflammationEndotheliumClopidogrelHeart failureCoronary artery diseasePulse wave velocityDiseaseEndothelial dysfunctionVascular functionIn patientMyocardial infarctionDiabetes mellitusBioinformaticsMedicine
443Publications
32H-index
3,817Citations
Publications 445
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#1Edina Cenko (UNIBO: University of Bologna)H-Index: 16
#2Lina BadimonH-Index: 99
Last. Etto C. Eringa (UM: Maastricht University)H-Index: 28
view all 23 authors...
The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19). Microvascular injury, endothelial dysfunction and thrombosis resulting from viral infection or indirectly related to the intense systemic inflammatory and immune responses are characteristic features of severe COVID-19. Pre-existing cardiovascular disease and viral load are linked to myocardial injury and worse outcomes. The vascular response to cytokine production and the interaction between SARS-CoV-2 and...
1 CitationsSource
#1Panagiotis Theofilis (UoA: National and Kapodistrian University of Athens)H-Index: 5
#2Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
Last. Dimitris Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 81
view all 9 authors...
Abstract null null Background null Pro-angiogenic microRNA modulation is a potentially attractive approach in the management of peripheral artery disease (PAD). The aim of this systematic review and meta-analysis was to examine the impact of microRNAs involved in the process of angiogenesis on blood flow recovery following hind limb ischemia induction in animal models. null null null Methods null A literature search was performed to identify studies testing the efficacy of microRNA treatment on ...
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#1Attila FeherH-Index: 12
#2Nabil E. BoutagyH-Index: 13
Last. Monique Hinchcliff (Yale University)H-Index: 36
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BACKGROUND Coronary microvascular dysfunction has been described in patients with autoimmune rheumatic disease (ARD). However, it is unknown whether positron emission tomography (PET)-derived myocardial flow reserve (MFR) can predict adverse events in this population. METHODS Patients with ARD without coronary artery disease who underwent dynamic rest-stress 82Rubidium PET were retrospectively studied and compared with patients without ARD matched for age, sex, and comorbidities. The association...
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#1Georgios Koutsis (UoA: National and Kapodistrian University of Athens)H-Index: 19
#2Efstathios Kastritis (UoA: National and Kapodistrian University of Athens)H-Index: 66
Last. Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
view all 23 authors...
Comprehensive data on variant transthyretin amyloidosis polyneuropathy (ATTRv-PN) in Greece are lacking. We presently provide an overview of ATTRv-PN in Greece, focusing on unexplored non-endemic regions of the country. In total, we identified 57 cases of ATTRv-PN diagnosed over the past 25 years, including 30 from the island of Crete, an apparent endemic region. Patients carried 10 different TTR mutations (C10R; P24S; V30M; R34G; R34T; I68L; A81T; E89Q; E89K and V94A). Carriers of the common V3...
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#1Evangelos Oikonomou (Yale University)H-Index: 32
#2Alexios S. Antonopoulos (University of Oxford)H-Index: 28
Last. Michail C Mavrogiannis (University of Oxford)
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AIMS Coronary CT angiography (CCTA) is a first-line modality in the investigation of suspected coronary artery disease (CAD). Mapping of perivascular Fat Attenuation Index (FAI) on routine CCTA enables the non-invasive detection of coronary artery inflammation by quantifying spatial changes in perivascular fat composition. We now report the performance of a new medical device, CaRi-Heart®, which integrates standardised FAI mapping together with clinical risk factors and plaque metrics to provide...
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#1Marios Sagris (UoA: National and Kapodistrian University of Athens)H-Index: 2
#2Alexios S. Antonopoulos (University of Oxford)H-Index: 28
Last. Dimitris Tousoulis (UoA: National and Kapodistrian University of Athens)H-Index: 81
view all 10 authors...
Myocardial infarction (MI) among young adults (< 45 years) represents a considerable proportion of the total heart attack incidents. The underlying pathophysiologic characteristics, atherosclerotic plaque features and risk factors profile differ between young and older patients with MI. This review article discusses the main differences between the younger and elderly MI patients as well as the different pathogenic mechanisms underlying the development of MI in the younger. Young patients with M...
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#1Evangelos Oikonomou (UoA: National and Kapodistrian University of Athens)H-Index: 32
#2George Lazaros (UoA: National and Kapodistrian University of Athens)H-Index: 23
Last. M.N. Assimakopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 22
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Abstract null null Background null Air pollution is a well-described environmental factor with evidence suggesting a firm association with cardiovascular diseases. The purpose of this study was to determine the association of exposure to gaseous air pollutants on atherosclerosis burden. null null null Methods null 1955 inhabitants of the Corinthia region, aged 40 years or older, underwent clinical and biochemical assessment as well as carotid ultrasonography to evaluate carotid intima-media thic...
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#1Christos P. Kotanidis (University of Oxford)H-Index: 6
#2Evangelos Oikonomou (University of Oxford)H-Index: 32
Last. Keith M. Channon (University of Oxford)H-Index: 96
view all 12 authors...
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#1H Kondo (John Radcliffe Hospital)H-Index: 1
#2Ioannis Akoumianakis (John Radcliffe Hospital)H-Index: 10
Last. Maria Cristina Carena (John Radcliffe Hospital)H-Index: 1
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Aims null Recent clinical trials indicate that sodium-glucose cotransporter 2 (SGLT2) inhibitors improve cardiovascular outcomes in heart failure patients, but the underlying mechanisms remain unknown. We explored the direct effects of canagliflozin, an SGLT2 inhibitor with mild SGLT1 inhibitory effects, on myocardial redox signalling in humans. null Methods and results null Study 1 included 364 patients undergoing cardiac surgery. Right atrial appendage biopsies were harvested to quantify super...
2 CitationsSource