Paul Muhle
University of Münster
AirwayBolus (medicine)SwallowingInternal medicineSurgeryRandomized controlled trialPediatricsProspective cohort studyStimulationNeurostimulationPresbyphagiaOropharyngeal dysphagiaTranscranial direct-current stimulationRehabilitationDiseaseParkinson's diseaseDysphagiaMyositisAspiration pneumoniaHypesthesiaPharyngeal ResidueStroke patientCough reflexAnesthesiaSalivaStrokeMedicineBiomarker (medicine)GastroenterologySensory systemPhysical medicine and rehabilitation
41Publications
10H-index
312Citations
Publications 41
Newest
#1Paul MuhleH-Index: 10
Last. Rainer DziewasH-Index: 11
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Background Removal of a tracheostomy tube in critically ill neurologic patients is a critical issue during intensive care treatment, particularly due to severe dysphagia and insufficient airway protection. The "Standardized Endoscopic Evaluation for Tracheostomy Decannulation in Critically Ill Neurologic Patients" (SESETD) is an objective measure of readiness for decannulation. This protocol includes the stepwise evaluation of secretion management, spontaneous swallowing, and laryngeal sensitivi...
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#1Bendix Labeit (WWU: University of Münster)H-Index: 5
#2Ksenia Perlova (WWU: University of Münster)
Last. Tobias Warnecke (WWU: University of Münster)H-Index: 30
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INTRODUCTION Oropharyngeal dysphagia is a clinical hallmark of idiopathic inflammatory myopathy (IIM). This study investigated predictors, outcome, and characteristics of oropharyngeal dysphagia in patients with different types of IIM. METHODS Flexible endoscopic evaluation of swallowing (FEES) videos of 71 IIM patients were retrospectively analysed for bolus spillage, penetration, aspiration, and pharyngeal residue. Based on these findings, dysphagia severity was rated. Regression analyses were...
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#1Inga ClausH-Index: 6
#2Paul MuhleH-Index: 10
Last. Tobias WarneckeH-Index: 30
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BACKGROUND Pharyngeal dysphagia in Parkinson's disease (PD) is a common and clinically relevant symptom associated with poor nutrition intake, reduced quality of life, and aspiration pneumonia. Despite this, effective behavioral treatment approaches are rare. OBJECTIVE The objective of this study was to verify if 4 week of expiratory muscle strength training can improve pharyngeal dysphagia in the short and long term and is able to induce neuroplastic changes in cortical swallowing processing. M...
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#1Bendix Labeit (WWU: University of Münster)H-Index: 5
#2Inga Claus (WWU: University of Münster)H-Index: 6
Last. Tobias Warnecke (WWU: University of Münster)H-Index: 30
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BACKGROUND Dysphagia frequently occurs in patients with Parkinson's disease (PD) and is associated with severe complications. However, the underlying pathology is poorly understood at present. This study investigated the effect of cognitive and motor dual-task interference on oropharyngeal swallowing in PD. METHODS Thirty PD patients (23 men, mean age 65.90 ± 9.32 years, mean Hoehn and Yahr stage 2.62 ± 0.81, mean UPDRS 18.00 ± 7.18) were examined using flexible endoscopic evaluation of swallowi...
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#1Paul MuhleH-Index: 10
#2Bendix LabeitH-Index: 5
Last. Sonja Suntrup-KruegerH-Index: 9
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Pharyngolaryngeal hypesthesia is a major reason for dysphagia in various neurological diseases. Emerging neuromodulation devices have shown potential to foster dysphagia rehabilitation, but the optimal treatment strategy is unknown. Because functional imaging studies are difficult to conduct in severely ill patients, we induced a virtual sensory lesion in healthy volunteers and evaluated the effects of central and peripheral neurostimulation techniques. In a sham-controlled intervention study wi...
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#1Rainer DziewasH-Index: 11
Last. Paul MuhleH-Index: 10
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Importance Dysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims. Objectives To investigate dysphagia in patients with severe coronavirus disease 2019. Design setting and participants In this case series, we report results of dedicated evaluation of swallowing function in six consecutive, tracheotomized coronavirus disease 2019 patients after they had survived acute respiratory distress syndrome and...
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#2Paul MuhleH-Index: 10
Last. Rainer DziewasH-Index: 42
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Oropharyngeal dysphagia is prevalent in age-related neurological disorders presenting with impaired efficacy and safety of swallowing due to a loss of muscle force and sensory deficits. Stimulating the oropharynx with capsaicin that mediates Substance P release is an emerging pharmacological treatment option which needs further scientific evidence. Our aim was to comprehensively evaluate the effect of capsaicin on biochemical, neurophysiological, and biomechanical parameters of swallowing functi...
1 CitationsSource
#1Tobias WarneckeH-Index: 30
#2Bendix Labeit (WWU: University of Münster)H-Index: 5
Last. Rainer DziewasH-Index: 42
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Objective: Introduction and validation of a phenotypic classification of neurogenic dysphagia based on flexible endoscopic evaluation of swallowing (FEES). Methods: A systematic literature review was conducted, searching MEDLINE from inception to 05/2020 for FEES findings in neurological diseases of interest. Based on a retrospective analysis of FEES-videos in neurological diseases and considering the results from the review, a classification of neurogenic dysphagia was developed distinguishing ...
1 CitationsSource
#1Paul Muhle (WWU: University of Münster)H-Index: 10
#2Inga ClausH-Index: 6
Last. Tobias WarneckeH-Index: 30
view all 7 authors...
Dysphagia is frequent in many neurological diseases and gives rise to severe complications such as malnutrition, dehydration and aspiration pneumonia. Therefore, early detection and management of dysphagia is essential and can reduce mortality. This study investigated the effect of cognitive and motor dual-task interference on swallowing in healthy participants, as dual-task effects are reported for other motor tasks such as gait and speech. 27 participants (17 females; 29.2 ± 4.1 years) were in...
1 CitationsSource
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