Kimberly A. Holst
Mayo Clinic
Cardiac function curveInterquartile rangeInternal medicineRadiologyPeripheral blood mononuclear cellSurgeryUnivariate analysisCardiologyIntensive care medicineProspective cohort studyCohort studyMedical prescriptionHeart failureCardiac surgeryCardiomyopathyVentricleConcomitantStem-cell therapyMEDLINEMedian sternotomyImplantable loop recorderTricuspid valveValve replacementHeart diseaseRegurgitation (circulation)Hypertrophic cardiomyopathyOpioidEBSTEIN ANOMALYRight ventricular dysfunctionTranscatheter aorticMedicineRibonucleoprotein
Publications 33
#1Patrick W. O'Leary (Mayo Clinic)H-Index: 40
#2M. Yasir Qureshi (Mayo Clinic)H-Index: 5
Last. Angela R. MillerH-Index: 2
view all 15 authors...
Abstract null null Objective null To define the impact of tricuspid valve cone reconstruction (CR) on ventricular performance in Ebstein anomaly, both independently and after stem cell therapy. null null null Patients and Methods null The control group included 257 patients who had CR between June 2007 and December 2019. Ten subjects of a phase I stem cell therapy trial (May 2017 – March 2019) were compared with the controls to assess the echocardiographic impact on ventricular remodeling. null ...
#1Kimberly A. Holst (Mayo Clinic)H-Index: 9
#2Elizabeth B. Habermann (Mayo Clinic)H-Index: 50
Last. Joseph A. Dearani (Mayo Clinic)H-Index: 95
view all 3 authors...
#7Wei Guo (UW: University of Wyoming)
#1J.W. Awori Hayanga (WVU: West Virginia University)H-Index: 10
#2Donald S. LikoskyH-Index: 38
Last. Rakesh C. AroraH-Index: 44
view all 9 authors...
#2Joseph A. Dearani (UR: University of Rochester)H-Index: 95
#5Bryan C. Cannon (UR: University of Rochester)H-Index: 29
Last. Karen Cavanaugh (Mayo Clinic)H-Index: 2
view all 13 authors...
Abstract Background The objective of this study is to assess the safety and early impact of intramyocardial delivery of autologous bone marrow-derived mononuclear cells (BM-MNC) at time of surgical Ebstein repair. Methods Patients with EA (ages 6 months to 30 years) scheduled to undergo repair of the TV were eligible to participate in this open label, non-randomized Phase I clinical trial. BM-MNC target dose was 1-3 million cells/kg. Ten patients have undergone surgical intervention and cell del...
2 CitationsSource
#7Wei Guo (UW: University of Wyoming)
Ribonucleoprotein (RNP) granules are biomolecular condensates-liquid-liquid phase-separated droplets that organize and manage messenger RNA metabolism, cell signaling, biopolymer assembly, biochemical reactions and stress granule responses to cellular adversity. Dysregulated RNP granules drive neuromuscular degenerative disease but have not previously been linked to heart failure. By exploring the molecular basis of congenital dilated cardiomyopathy (DCM) in genome-edited pigs homozygous for an ...
11 CitationsSource