Véronique Migonney
Institut Galilée
Radical polymerizationSurface modificationBiophysicsBiomedical engineeringAdsorptionMonomerChemistryPolymer chemistryMaterials scienceGraftingStyrenePolystyreneBiomaterialSulfonateChemical engineeringPolymerizationTitaniumPolymerAdhesionCell adhesionProtein adsorption
129Publications
25H-index
1,861Citations
Publications 129
Newest
#1Juan Carlos Chachques (University of Paris)H-Index: 28
#2Chiara GardinH-Index: 22
Last. Tiberio RoccaH-Index: 1
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A challenge in contractile restoration of myocardial scars is one of the principal aims in cardiovascular surgery. Recently, a new potent biological tool used within healing processes is represented by exosomes derived from mesenchymal stem cells (MSCs). These cells are the well-known extracellular nanovesicles released from cells to facilitate cell function and communication. In this work, a combination of elastomeric membranes and exosomes was obtained and tested as a bioimplant. Mesenchymal s...
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#1Jean-Sébastien Baumann (ISPG: Institut Galilée)
#2Emile Jubeli (University of Paris-Sud)H-Index: 12
Last. Céline Falentin-Daudre (ISPG: Institut Galilée)H-Index: 1
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Abstract null null Objectives null To improve the hydrophilicity of cyclic olefin copolymer, a simple and rapid method using two-stage with ultraviolet irradiation was developed in order to graft a bioactive polymer on the surface of these polymers. null null null Materials and Methods null A bioactive polymer, poly(sodium styrene sulfonate) was grafting in two steps on the cyclic olefin copolymer surface. The process consists to activate the surface with ozone and grafting to under UV irradiati...
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#1Jagadeesh K. Venkatesan (Saarland University)H-Index: 16
#2Xiaoyu Cai (Saarland University)H-Index: 10
Last. Magali Cucchiarini (Saarland University)H-Index: 41
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Scaffold-guided viral gene therapy is a novel, powerful tool to enhance the processes of tissue repair in articular cartilage lesions via the delivery and overexpression of therapeutic genes in a non-invasive, controlled release manner based on a procedure that may protect the gene vehicles from undesirable host immune responses. In the present study, we examined the potential of transferring a recombinant adeno-associated virus (rAAV) vector carrying a sequence for the highly chondroregenerativ...
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#1Jagadeesh K. Venkatesan (Saarland University)H-Index: 16
#1J.K. Venkatesan (Saarland University)H-Index: 5
Last. Magali Cucchiarini (Saarland University)H-Index: 41
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Abstract Biomaterial-assisted gene therapy is a promising strategy for the treatment of various musculoskeletal disorders such as those concerning the articular cartilage, bones, tendons and ligaments, and meniscus as it can deliver candidate gene sequences in a spatially and temporally controlled manner in sites of tissue damage over prolonged periods of time that may be required to durably enhance the specific, natural repair mechanisms in vivo in direct, non-invasive procedures that avoid the...
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#1Tuan Ngoc Nguyen (Sorbonne)H-Index: 1
#2André Luiz Reis Rangel (Sorbonne)H-Index: 3
Last. Véronique Migonney (Sorbonne)H-Index: 25
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Polyethylene terephthalate (PET) fibers and fabrics are widely used for medical device applications such as vascular and anterior cruciate ligament prostheses. Several years ago, we began functionalizing PET fabrics using anionic polymers to enhance their biocompatibility, cell adhesion, proliferation and functional performance as PET ligament prostheses. Polymer functionalization followed a grafting-from process from virgin PET surfaces subject to spin-finish oil additive removal under Soxhlet ...
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#1Mylan Lam (ISPG: Institut Galilée)H-Index: 2
#2Véronique Migonney (ISPG: Institut Galilée)H-Index: 25
Last. Céline Falentin-Daudre (ISPG: Institut Galilée)H-Index: 1
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Abstract Silicone implants are widely used in the medical field for plastic or reconstructive surgeries for the purpose of soft tissue issues. However, as with any implanted object, healthcare-associated infections are not completely avoidable. The material suffers from a lack of biocompatibility and is often subject to bacterial/microbial infections characterized by biofilm growth. Numerous strategies have been developed to either prevent, reduce, or fight bacterial adhesion by providing an ant...
5 CitationsSource
#1Andre Rangel (Sorbonne)H-Index: 1
#1André Luiz Reis Rangel (Sorbonne)H-Index: 3
Last. Véronique Migonney (Sorbonne)H-Index: 25
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1 CitationsSource
#1Amélie Leroux (ISPG: Institut Galilée)H-Index: 4
#2Tuan Ngoc Nguyen (ISPG: Institut Galilée)H-Index: 1
Last. Véronique Migonney (ISPG: Institut Galilée)H-Index: 25
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Polycaprolactone (PCL) is a widely used biodegradable polyester for tissue engineering applications when long-term degradation is preferred. In this article, we focused on the analysis of the hydrolytic degradation of virgin and bioactive poly(sodium styrene sulfonate) (pNaSS) functionalized PCL surfaces under simulated physiological conditions (phosphate buffer saline at 25 and 37 °C) for up to 120 weeks with the aim of applying bioactive PCL for ligament tissue engineering. Techniques used to ...
4 CitationsSource
#1Andre Rangel (Sorbonne)H-Index: 1
#1André Luiz Reis Rangel (Sorbonne)H-Index: 3
Last. Véronique Migonney (Sorbonne)H-Index: 25
view all 6 authors...
Abstract Background and objective Over the past decades, anterior cruciate ligament injuries have become a considerable public health issue. Due to specific physiological conditions such injuries often demand replacement surgery and can take up to two years to a complete recovery. Using biomaterials able to accelerate the healing process could represent a remarkable progress in the field. The main goal of this article is, therein, to evaluate the mechanical properties of poly(e-caprolactone) (PC...
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