Maria Grazia Daidone
University of Milan
CancerPathologyOncologyCellMolecular biologyTelomereApoptosisChemotherapyMammary glandCisplatinCancer researchBreast cancerCirculating tumor cellCell growthMedicineBiomarker (medicine)Cell cultureEstrogen receptorBiologyTelomerase
Publications 342
Abstract Study Objective There are growing concerns on the potential risk of COVID-19 transmission during surgery and in particular during minimally invasive procedure, due to the aerosolization of SARS-CoV-2 particles. However, no study demonstrated this hypothesis. Here, we aimed to investigate the presence SARS-CoV-2 through surgical smoke. Design A prospective pilot study. Setting A third-level cancer center in Northern Italy. Patients Overall, 17 patients had laparoscopic approach for the m...
#1Serena Di CosimoH-Index: 28
#2Luca PorcuH-Index: 15
Last. Evandro de Azambuja (ULB: Université libre de Bruxelles)H-Index: 47
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#1Silvia MartiniH-Index: 3
#2Mariangela FiginiH-Index: 26
Last. Alessandro SattaH-Index: 4
view all 12 authors...
Triple-negative breast cancer (TNBC) is an aggressive disease with poor prognosis and limited therapeutic options. Recent advances in the immunotherapy field have enabled the development of new treatment strategies, among which the use of bispecific antibodies (BsAbs), able to redirect T cells against tumors, has shown promising results. In particular, a BsAb that uses TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) as a target was constructed and demonstrated good results in redirec...
2 CitationsSource
#1Carolina ReduzziH-Index: 5
#2Youbin ZhangH-Index: 2
Last. Massimo CristofanilliH-Index: 76
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In biliary tract cancer (BTC), tissue biopsies to guide treatment are rarely feasible, thus implementing liquid biopsy approaches to improve patient management represents a priority. So far, studies on circulating tumor cells (CTCs) in BTC are insufficient to promote their use in patient clinical management and are limited to EpCAM-enriched CTCs evaluated with the CellSearch. We applied a single-cell protocol allowing identification not only of epithelial CTCs (eCTCs), but also of nonconventiona...
1 CitationsSource
1 CitationsSource
#1Franco Valenza (University of Milan)H-Index: 28
#2Gabriele PapagniH-Index: 1
Last. Giovanni ApoloneH-Index: 52
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Background:The rapid spread of coronavirus disease (COVID-19) is affecting many countries. While healthcare systems need to cope with the need to treat a large number of people with different degre...
15 CitationsSource
#1M.C. De SantisH-Index: 1
#2E. La RoccaH-Index: 1
Last. S. Di CosimoH-Index: 15
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Background Primary tumor characteristics, which are readily available to all clinicians, may aid in selecting the optimal adjuvant therapy for patients with breast cancer (BC). Herein, we investigated the relationship between tumor size, hormone receptor and HER2 status, Ki67 and age with axillary lymph node metastases (ALNM) in early-BC patients.
#1S. Di CosimoH-Index: 15
#2Valentina AppiertoH-Index: 15
Last. Maria Grazia DaidoneH-Index: 59
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Circulating tumor cells (CTCs) are promising biomarkers for prognosis, therapeutic response prediction, and treatment monitoring in cancer patients. Despite its epithelial origin, renal cell carcinoma (RCC) shows low expression of epithelial markers hindering CTC-enrichment approaches exploiting epithelial cell surface proteins. In 21 blood samples serially collected from 10 patients with metastatic RCC entering the TARIBO trial, we overcame this limitation using the marker-independent Parsortix...
3 CitationsSource
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