Armando Manduca
Mayo Clinic
Imaging phantomOpticsPhysicsRadiologyBiomedical engineeringIterative reconstructionMagnetic resonance imagingArtificial intelligenceMaterials scienceAcousticsElastographyMagnetic resonance elastographyStiffnessShear wavesElasticity Imaging TechniquesNuclear medicineComputer visionComputer scienceShear modulusImage qualityMedicine
290Publications
59H-index
12.7kCitations
Publications 281
Newest
#1Vinayak Kumar (Mayo Clinic)H-Index: 3
#2Armando Manduca (Mayo Clinic)H-Index: 59
Last. Nandan S. Anavekar (Mayo Clinic)H-Index: 25
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BACKGROUND Myocardial volume is assumed to be constant over the cardiac cycle in the echocardiographic models used by professional guidelines, despite evidence that suggests otherwise. The aim of this paper is to use literature-derived myocardial strain values from healthy patients to determine if myocardial volume changes during the cardiac cycle. METHODS A systematic review for studies with longitudinal, radial, and circumferential strain from echocardiography in healthy volunteers ultimately ...
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#1Brototo DebH-Index: 1
#2Armando ManducaH-Index: 59
Last. Adil E. BharuchaH-Index: 69
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#1Armando Manduca (Mayo Clinic)H-Index: 59
#2Philip J. Bayly (WashU: Washington University in St. Louis)H-Index: 1
Last. Bernard E. Van Beers (University of Paris)H-Index: 52
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Magnetic resonance elastography (MRE) is a phase contrast-based MRI technique that can measure displacement due to propagating mechanical waves, from which material properties such as shear modulus can be calculated. Magnetic resonance elastography can be thought of as quantitative, noninvasive palpation. It is increasing in clinical importance, has become widespread in the diagnosis and staging of liver fibrosis, and additional clinical applications are being explored. However, publications hav...
10 CitationsSource
#1Ziying Yin (Mayo Clinic)H-Index: 11
#2Xin Lu (Mayo Clinic)H-Index: 1
Last. John Huston (Mayo Clinic)H-Index: 71
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To develop an objective quantitative method to characterize and visualize meningioma-brain adhesion using MR elastography (MRE)-based slip interface imaging (SII). This retrospective study included 47 meningiomas (training dataset: n = 35; testing dataset: n = 12) with MRE/SII examinations. Normalized octahedral shear strain (NOSS) values were calculated from the acquired MRE displacement data. The change in NOSS at the tumor boundary (ΔNOSSbdy) was computed, from which a 3D ΔNOSSbdy map of the ...
2 CitationsSource
#1Jiahui Li (Mayo Clinic)H-Index: 6
#2Tejasav S. Sehrawat (Mayo Clinic)H-Index: 9
Last. Meng Yin (Mayo Clinic)H-Index: 34
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To determine the potential of bi-parametric dual-frequency hepatic MR elastography (MRE) for predicting portal pressure (PP) in mouse models of portal hypertension (PHTN) with the presence of varying hepatic fibrosis. We studied 73 wild-type male mice, including 22 mice with hepatic congestion, 20 mice with cholestatic liver injury, and 31 age-matched sham mice. Hepatic shear stiffness (SS) and volumetric strain (VS) were calculated by 3D MRE acquired at 80 and 200 Hz. We measured PP immediately...
1 CitationsSource
#1Arvin Arani (Mayo Clinic)H-Index: 16
#2Armando Manduca (Mayo Clinic)H-Index: 59
Last. John Huston (Mayo Clinic)H-Index: 71
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Brain magnetic resonance elastography (MRE) is an imaging technique capable of accurately and non-invasively measuring the mechanical properties of the living human brain. Recent studies have shown...
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#1Yi Sui (Mayo Clinic)H-Index: 14
#2Arvin Arani (Mayo Clinic)H-Index: 16
Last. John Huston (Mayo Clinic)H-Index: 71
view all 11 authors...
PURPOSE To develop a novel magnetic resonance elastography (MRE) acquisition using a hybrid radial EPI readout scheme (TURBINE), and to demonstrate its feasibility to obtain wave images and stiffness maps in a phantom and in vivo brain. METHOD The proposed 3D TURBINE-MRE is based on a spoiled gradient-echo MRE sequence with the EPI readout radially rotating about the phase-encoding axis to sample a full 3D k-space. A polyvinyl chloride phantom and 6 volunteers were scanned on a compact 3T GE sca...
3 CitationsSource
#1Mayank Sharma (Mayo Clinic)H-Index: 7
#2Kelly Feuerhak (Mayo Clinic)H-Index: 6
Last. Adil E. Bharucha (Mayo Clinic)H-Index: 69
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OBJECTIVES Defecation requires relaxation of the internal and external anal sphincters. High anal resting pressure is associated with painful constipation, defecatory disorders, and increased healthcare utilization in constipated patients; the mechanisms are unclear. Perhaps patients with a high anal resting pressure have a less distensible canal, which impedes defecation. METHODS In 50 of 64 participants (33 healthy and 17 constipated women), anal pressures and distensibility were measured, res...
1 CitationsSource
Ultrasound vascular imaging based on ultrafast plane wave imaging and singular value decomposition (SVD) clutter filtering has demonstrated superior sensitivity in blood flow detection. However, ultrafast ultrasound vascular imaging is susceptible to electronic noise due to the weak penetration of unfocused waves, leading to a lower signal-to-noise ratio (SNR) at larger depths. In addition, incoherent clutter artifacts originating from strong and moving tissue scatterers that cannot be completel...
2 CitationsSource
#1Gabriel Martínez-Gálvez (Mayo Clinic)H-Index: 6
#2Parnal Joshi (Iowa State University)
Last. Stephen C. Ekker (Mayo Clinic)H-Index: 61
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Gene-editing experiments commonly elicit the error-prone non-homologous end joining for DNA double-strand break (DSB) repair. Microhomology-mediated end joining (MMEJ) can generate more predictable outcomes for functional genomic and somatic therapeutic applications. We compared three DSB repair prediction algorithms - MENTHU, inDelphi, and Lindel - in identifying MMEJ-repaired, homogeneous genotypes (PreMAs) in an independent dataset of 5,885 distinct Cas9-mediated mouse embryonic stem cell DSB...
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